Atomic scale imaging with high coherence electrons and ions. This project aims to combine a cold atom electron-ion source with a commercial microscope column for atomic-scale imaging in biosciences and materials science. Nanoscale imaging with electron and ion microscopy are tools for investigating the world at the atomic scale, underpinning development in modern technologies from semiconductor devices to medical treatments. This project will use ideas from laser cooling of atoms and atom optics ....Atomic scale imaging with high coherence electrons and ions. This project aims to combine a cold atom electron-ion source with a commercial microscope column for atomic-scale imaging in biosciences and materials science. Nanoscale imaging with electron and ion microscopy are tools for investigating the world at the atomic scale, underpinning development in modern technologies from semiconductor devices to medical treatments. This project will use ideas from laser cooling of atoms and atom optics to achieve new imaging modalities for time-lapse imaging of fundamental processes at the nano-scale. It will allow increasingly small scale resolution of fundamental processes at the nano-scale.Read moreRead less
Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn ....Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.Read moreRead less
Novel concepts for bioelectrochemical generation of renewable fuels and chemicals from wastewater. Global warming and the diminishing fossil fuel resources are posing an ever increasing threat to our societies and economies. This project aims to develop novel and highly innovative bioelectrochemical processes for the production of valuable fuels and chemicals from wastewater, which is a largely untapped renewable resource.
Tissue Bio-physicochemical Quantification Using Magnetic Resonance Imaging. This project aims to develop novel magnetic resonance imaging methods to investigate tissue structure and function. Current MRI technologies use standard water-based contrast mechanisms to generate images with limited tissue information. In contrast, this project expects to provide a non-invasive, ultra-high-resolution MRI technology that measures the electrical, magnetic, and chemical signals generated from the human bo ....Tissue Bio-physicochemical Quantification Using Magnetic Resonance Imaging. This project aims to develop novel magnetic resonance imaging methods to investigate tissue structure and function. Current MRI technologies use standard water-based contrast mechanisms to generate images with limited tissue information. In contrast, this project expects to provide a non-invasive, ultra-high-resolution MRI technology that measures the electrical, magnetic, and chemical signals generated from the human body. Thus, the new imaging methods can probe deeper biological functionality while examining tissue structure. The potential benefits include: expanding the scope and capabilities of current MRI, facilitating a wide range of imaging-based research and applications, and accelerating knowledge expansion in life science.Read moreRead less
Digital media, location awareness, and the politics of geodata. This project aims to examine the increasingly pervasive role of location metadata, or geodata, in Australian smartphone practices and cultures and the implications this has for users, industry, and public administration. The project will deliver online and open resources to enhance public understanding of geodata and geoprivacy, as well as industry and policy recommendations that address the crucial issue of ‘location awareness’ in ....Digital media, location awareness, and the politics of geodata. This project aims to examine the increasingly pervasive role of location metadata, or geodata, in Australian smartphone practices and cultures and the implications this has for users, industry, and public administration. The project will deliver online and open resources to enhance public understanding of geodata and geoprivacy, as well as industry and policy recommendations that address the crucial issue of ‘location awareness’ in everyday digital media use. The project will generate new insights into the critical role of geodata in everyday digital media use and will contribute to broader public discussion about data privacy, surveillance and cybersecurity. Its findings will also provide industry benefits, enhancing developers’ understanding of how everyday users apprehend and negotiate the privacy implications of location services.Read moreRead less
New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordi ....New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordinary people to gain knowledge about the concentrations of molecular compounds in their environments and in themselves. This will stimulate economic and social benefits related to environmental testing and early disease diagnosis and generate new commercial opportunities for the Australian biotechnology industry.Read moreRead less
Establishing Design Principles Of Polymers For Intracellular Delivery . Engineered polymers have played a central role in the field of bionanotechnology by enabling targeted nanoscale cell interactions. Progress in the field of intracellular delivery is currently affected by a major bottleneck due to the absence of effective polymers that is applicable across the range of bimolecular cargoes. In essence depending on the type of cargo: DNA, RNA or protien, the polymer needs programmability. The l ....Establishing Design Principles Of Polymers For Intracellular Delivery . Engineered polymers have played a central role in the field of bionanotechnology by enabling targeted nanoscale cell interactions. Progress in the field of intracellular delivery is currently affected by a major bottleneck due to the absence of effective polymers that is applicable across the range of bimolecular cargoes. In essence depending on the type of cargo: DNA, RNA or protien, the polymer needs programmability. The limited tunability of traditional polymers agents makes them unsuitable for this particular application. The multidisciplinary project addresses this significant problem by engineering novel sequences of defined polymer based nanoscale agents to achieve efficient delivery in cells.Read moreRead less
Framing and Enabling Children’s Active Play using Novel Technology. This project aims to address inactivity in the 3-5 age group through understanding and exploring innovative interactive active play experiences for children, with a view to increasing their physical activity over the long term. This project will be based on empirical research with real children undertaking real interactive experiences in real contexts, in order to understand issues around sustained engagement with these types of ....Framing and Enabling Children’s Active Play using Novel Technology. This project aims to address inactivity in the 3-5 age group through understanding and exploring innovative interactive active play experiences for children, with a view to increasing their physical activity over the long term. This project will be based on empirical research with real children undertaking real interactive experiences in real contexts, in order to understand issues around sustained engagement with these types of systems. We will design and develop solutions that may address the issues and test those interventions in a longitudinal manner. The outcome will be a framework which can be applied in a variety of situations and modalities by designers and developers of such systems, and feed into childhood technology guidelines.
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Digital China: From cultural presence to innovative nation. This project aims to investigate how digital platforms and technologies help Chinese culture and ideas reach the world. While China's global cultural presence has increased, it is not seen as an innovative nation. The project examines how the Chinese government’s internet+ strategy changes power dynamics among political institutions, commercially motivated digital companies and online communities. The project will investigate internatio ....Digital China: From cultural presence to innovative nation. This project aims to investigate how digital platforms and technologies help Chinese culture and ideas reach the world. While China's global cultural presence has increased, it is not seen as an innovative nation. The project examines how the Chinese government’s internet+ strategy changes power dynamics among political institutions, commercially motivated digital companies and online communities. The project will investigate internationalisation strategies and consumption of Chinese culture on digital platforms in China, Australia, Hong Kong, Singapore and South Korea. It expects to understand the implications of China's digital ascendency and the lessons for Australia in the post-resources boom era.Read moreRead less
New entropy measures of short term signals for smart wearable devices. This project aims to improve reliability and accuracy of wearable devices by developing a new set of computationally efficient algorithms. Wearable devices can be very effective in remote and continuous monitoring to detect short or bursty anomalous events. Present devices are unable to detect such events effectively due to limited capability in processing short length signal. This project will provide computationally efficie ....New entropy measures of short term signals for smart wearable devices. This project aims to improve reliability and accuracy of wearable devices by developing a new set of computationally efficient algorithms. Wearable devices can be very effective in remote and continuous monitoring to detect short or bursty anomalous events. Present devices are unable to detect such events effectively due to limited capability in processing short length signal. This project will provide computationally efficient algorithms for signal quality analysis and enhanced feature extraction methods in resource constrained wearable devices. This will improve the reliability and performance of wearable devices for adoption in intelligent decision-making systems.Read moreRead less