THE ROLE OF TUMOUR-EGRESSING T CELLS IN ANTI-TUMOUR IMMUNE RESPONSES
Funder
National Health and Medical Research Council
Funding Amount
$603,333.00
Summary
Immune cells can play both beneficial and detrimental roles in cancer. We have devised a novel method to ‘tag’ immune cells inside tumours and follow their fate. Using this method we discovered that immune cells called T cells can leave primary tumours and migrate to lymph nodes. The aim of this project is to investigate the role of these tumour-egressing cells in tumour immunity and to determine whether their migration and function can be manipulated to improve anti-tumour therapies.