Language, belief formation and visual cognition: cognitive and neuropsychological investigations. I will direct a programme of research and research training in cognitive science and cognitive neuropsychology at macquarie universtiy, with international collaborative links to the USA, Canada, France, Italy, Spain, Germany & New Zealand. This programme of research and research training will initially focus on
a)how people understand and produce language, and how these capabilities can break down ....Language, belief formation and visual cognition: cognitive and neuropsychological investigations. I will direct a programme of research and research training in cognitive science and cognitive neuropsychology at macquarie universtiy, with international collaborative links to the USA, Canada, France, Italy, Spain, Germany & New Zealand. This programme of research and research training will initially focus on
a)how people understand and produce language, and how these capabilities can break down after brain damage;
b)The relationship between visual memory and reading; and
c)The nature of the delusions seen in schizophrenia and other disorders, and what causes these delusions.Read moreRead less
Long-term memory systems and the human brain. Impairment of memory is a ubiquitous feature of human brain disease. A better understanding of memory processing in the brain is key to the development of better tests for the detection and monitoring of disease progression as well as the application of improved methods of rehabilitation for patients with acquired brain injury. This project will provide the catalyst for the development of a National Memory Disorders Research Centre that would be the ....Long-term memory systems and the human brain. Impairment of memory is a ubiquitous feature of human brain disease. A better understanding of memory processing in the brain is key to the development of better tests for the detection and monitoring of disease progression as well as the application of improved methods of rehabilitation for patients with acquired brain injury. This project will provide the catalyst for the development of a National Memory Disorders Research Centre that would be the focus for multidisciplinary cognitive neuroscience research. The ultimate aim would be the translation of basic neuroscience into effective tools that will impact the health outcome of the ageing population.Read moreRead less
Human long-term memory and social cognition: an integrated cognitive neuroscience approach. Impairment of memory is a ubiquitous feature of the dementias and a better understanding of memory processing in the brain is key to the development of better tests for the early detection and monitoring of disease progression. The study of social cognition is relevant to a range of developmental, psychiatric and neurological disorders. This project will provide the catalyst for the development of a Natio ....Human long-term memory and social cognition: an integrated cognitive neuroscience approach. Impairment of memory is a ubiquitous feature of the dementias and a better understanding of memory processing in the brain is key to the development of better tests for the early detection and monitoring of disease progression. The study of social cognition is relevant to a range of developmental, psychiatric and neurological disorders. This project will provide the catalyst for the development of a National Memory and Cognitive Disorders Centre that would be the focus for multidisciplinary cognitive neuroscience research. The ultimate aim would be the translation of basic neuroscience into effective tools that will impact the health outcomes of the ageing population.Read moreRead less
Discovering genes and mechanisms regulating immune responses. The Fellowship will retain and expand a pioneering Australian research program, and attract to Australia major international investment and technology linkages, making use of the DNA sequence of humans and other mammals to advance understanding of immunity and infection control in public health, agriculture and industry. The program will build on Australia's pre-eminent research strengths in the field of immunity and infection, and w ....Discovering genes and mechanisms regulating immune responses. The Fellowship will retain and expand a pioneering Australian research program, and attract to Australia major international investment and technology linkages, making use of the DNA sequence of humans and other mammals to advance understanding of immunity and infection control in public health, agriculture and industry. The program will build on Australia's pre-eminent research strengths in the field of immunity and infection, and will create new knowledge and resources to improve human and animal health through vaccines, pharmaceuticals and public health policy. Read moreRead less
Cellular Plasticity in the Brain: discovering molecular mechanisms controlling the production of neurons during brain development, function, ageing and disease. The program aims to understand the mechanisms regulating Brain Plasticity - this recently discovered property of the brain to respond to environmental stimuli, both physiological and pathological, by producing new functional neurons. Specifically, the program will discover how the brain's stem cells are stimulated to produce new neurons. ....Cellular Plasticity in the Brain: discovering molecular mechanisms controlling the production of neurons during brain development, function, ageing and disease. The program aims to understand the mechanisms regulating Brain Plasticity - this recently discovered property of the brain to respond to environmental stimuli, both physiological and pathological, by producing new functional neurons. Specifically, the program will discover how the brain's stem cells are stimulated to produce new neurons. This understanding will significantly expand our knowledge of how the brain develops, and how functions, like memory, are modulated by neuronal replacement. Discoveries will underpin the development of, in association with Australia's biotechnology sector, a new generation of therapeutics, which treat neurological diseases, like Stroke, by stimulating the production of functional neurons.Read moreRead less
An investigation into Infection, Immunity & Rational Drug Design. The human population is constantly under threat of microbial attack. The survival of our species reflects a delicate balance between infection and immunity. Whether an individual mounts an effective immune response or succumbs to microbial infection is critically dependent on host proteins interacting effectively with microbial antigens, versus microbes developing sophisticated strategies of invasion and immune evasion. This pr ....An investigation into Infection, Immunity & Rational Drug Design. The human population is constantly under threat of microbial attack. The survival of our species reflects a delicate balance between infection and immunity. Whether an individual mounts an effective immune response or succumbs to microbial infection is critically dependent on host proteins interacting effectively with microbial antigens, versus microbes developing sophisticated strategies of invasion and immune evasion. This proposal will provide fundamental advancement of knowledge in the areas of infection and immunity. The information gleaned from this research will lead to the rational development of therapeutics. Consequently, the research will potentially have an enormous global impact in the area of biomedical health.Read moreRead less
In vivo imaging of the immune system in self tolerance and infectious disease. This proposal will introduce sophisticated imaging technology into our cutting-edge research program. Our approach will permit high resolution imaging of the immune response within an intact animal; currently not possible in Australia at the present time. The unique combination of technology and biological resources will significantly advance knowledge in key areas of basic immunology research. It will provide local ....In vivo imaging of the immune system in self tolerance and infectious disease. This proposal will introduce sophisticated imaging technology into our cutting-edge research program. Our approach will permit high resolution imaging of the immune response within an intact animal; currently not possible in Australia at the present time. The unique combination of technology and biological resources will significantly advance knowledge in key areas of basic immunology research. It will provide local researchers insights into how the body responds to infectious disease and immune-related disorders and be directly applicable to vaccine design. The facility and related research program will undoubtedly attract a team of top-level national and international scientists and students keen to work with this advanced technology.Read moreRead less