Addressing significant product safety knowledge gaps for older Australians . This project addresses significant gaps in contemporary knowledge of consumer product safety risks for older persons, with 25 years since the last Australian product safety research found older persons are at high risk of product-related injury/death. Products have evolved substantially and aged care models have changed in that time. This project generates contemporary knowledge of unsafe products causing injuries/death ....Addressing significant product safety knowledge gaps for older Australians . This project addresses significant gaps in contemporary knowledge of consumer product safety risks for older persons, with 25 years since the last Australian product safety research found older persons are at high risk of product-related injury/death. Products have evolved substantially and aged care models have changed in that time. This project generates contemporary knowledge of unsafe products causing injuries/deaths, risk factors/behaviours, and human rights issues. Outcomes benefiting the Australian community are improved prediction/characterisation of product safety issues for older Australians informing safer product design and use, targetted regulatory responses, ageing-in-place strategies, and creating safer home environments.Read moreRead less
Immunomodulatory Vaccines In The Treatment Of Peanut Allergy
Funder
National Health and Medical Research Council
Funding Amount
$678,899.00
Summary
Peanut allergy is the most common cause of food-induced anaphylactic reactions in Australia and is a major burden to our healthcare system. Current clinical practice advice dietary avoidance to prevent fatal anaphylactic responses. We propose the use of an immunomodulatory vaccine to re-write the immune response to peanut antigens, from an allergic to a tolerant phenotype. This study will provide novel insights into rational approaches for manipulating immune memory to food allergens.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100137
Funder
Australian Research Council
Funding Amount
$881,758.00
Summary
Australian Environmental Specimen Bank: advancing specimen bank capability. The aim of this LIEF is to advance Australia’s specimen banking capabilities through a new, enhanced national facility, the Australian Environmental Specimen Bank (AESB). The AESB would be founded on a unique current archive of human and environmental samples established by the partners to the LIEF. Importantly, the AESB would be managed as a nationally available (to all public sector researchers), operationally self-fun ....Australian Environmental Specimen Bank: advancing specimen bank capability. The aim of this LIEF is to advance Australia’s specimen banking capabilities through a new, enhanced national facility, the Australian Environmental Specimen Bank (AESB). The AESB would be founded on a unique current archive of human and environmental samples established by the partners to the LIEF. Importantly, the AESB would be managed as a nationally available (to all public sector researchers), operationally self-funded resource for integrated exposure research into the future. The archive is expected to support longitudinal and cross-sectional studies to assess trends in exposure to chemical and biological hazards in the Australian population, identify emerging hazards, and provide a scientific basis for policy and regulatory actions.Read moreRead less
From data to action: a new process for developing injury countermeasures. This project aims to understand how reporting systems can improve workplace safety. Workplace injury affects over 600 000 Australian workers per year at a cost of approximately $60 billion. Although the introduction of incident reporting systems has enabled organisations to better understand the causes of injuries, how to translate this knowledge into effective countermeasures remains ambiguous. Moreover, it is not clear w ....From data to action: a new process for developing injury countermeasures. This project aims to understand how reporting systems can improve workplace safety. Workplace injury affects over 600 000 Australian workers per year at a cost of approximately $60 billion. Although the introduction of incident reporting systems has enabled organisations to better understand the causes of injuries, how to translate this knowledge into effective countermeasures remains ambiguous. Moreover, it is not clear whether adopting incident reporting systems actually leads to a safety benefit. This research intends to tackle these critical knowledge gaps by developing, implementing, and testing a process for translating incident reporting system outputs into appropriate and effective injury countermeasures, and then evaluating the safety effects of adopting the new incident reporting and learning cycle.Read moreRead less
Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the h ....Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the health system. The data collected in this project will assist in developing health services to meet these needs.Read moreRead less
Estimating per capita use and release of chemicals by wastewater analysis. This project aims to systematically collect and analyse wastewater to assess human exposure to chemicals including drugs, pharmaceuticals, lifestyle chemicals and environmental pollutants. By combining temporal sampling from key sewage treatment plants with comprehensive nationwide sampling over the week of the 2016 census day, the project expects to estimate the per-capita human exposure to chemicals in the Australian po ....Estimating per capita use and release of chemicals by wastewater analysis. This project aims to systematically collect and analyse wastewater to assess human exposure to chemicals including drugs, pharmaceuticals, lifestyle chemicals and environmental pollutants. By combining temporal sampling from key sewage treatment plants with comprehensive nationwide sampling over the week of the 2016 census day, the project expects to estimate the per-capita human exposure to chemicals in the Australian population. Accurate and objective per-capita based consumption and release estimates for a wide range of chemicals is intended to provide a baseline against which to measure changes in our chemosphere.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH170100013
Funder
Australian Research Council
Funding Amount
$2,962,655.00
Summary
ARC Research Hub for Digital Enhanced Living. The ARC Research Hub for Digital Enhanced Living aims to address the growing challenges of aging people living in their own home or residential care. This will be through inventing new personalised medical technologies through an innovative approach, with a multi-disciplinary team leveraging diverse expertise. An enhanced capacity to create and deploy fit-for-purpose personalised health solutions will result in revenues from new and repurposed device ....ARC Research Hub for Digital Enhanced Living. The ARC Research Hub for Digital Enhanced Living aims to address the growing challenges of aging people living in their own home or residential care. This will be through inventing new personalised medical technologies through an innovative approach, with a multi-disciplinary team leveraging diverse expertise. An enhanced capacity to create and deploy fit-for-purpose personalised health solutions will result in revenues from new and repurposed devices, analytics and integration platforms. New jobs and improved care will see cost reductions, better use of resources and enhanced mental, physical and social well-being.Read moreRead less
Estimating use of tobacco and nicotine products through wastewater analysis. This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alter ....Estimating use of tobacco and nicotine products through wastewater analysis. This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alternative nicotine products. The outcomes of this project will provide reliable, cost-effective estimates of tobacco consumption for use with wastewater-based epidemiology assessments. This will enable changes in tobacco use to be accurately evaluated for the first time and improve the efficacy of tobacco control measures.Read moreRead less
Evaluating consumer product regulatory responses to improve child safety. This project aims to quantify the level of similarity between consumer product regulatory practices and child injuries, and compare national approaches. Consumer product safety regulation operates in a global and ‘virtual’ market. Online purchasing, limited border protection and distance between suppliers and consumers make monitoring and enforcing product safety more difficult for regulators, putting consumers at risk. A ....Evaluating consumer product regulatory responses to improve child safety. This project aims to quantify the level of similarity between consumer product regulatory practices and child injuries, and compare national approaches. Consumer product safety regulation operates in a global and ‘virtual’ market. Online purchasing, limited border protection and distance between suppliers and consumers make monitoring and enforcing product safety more difficult for regulators, putting consumers at risk. A rapid responsive product safety system that operates across sectors and borders is an international priority. This project expects to close gaps in consumer regulatory practice and safety policy.Read moreRead less