RNA-binding proteins rewire transcriptomes in immune cell differentiation. This project aims to combine advanced computational and experimental techniques to investigate a new layer of gene regulation by novel RNA binding proteins (RBP) which control messenger RNA length in immune cells. This project expects to demonstrate that these RBPs have a profound effect on immune cell differentiation and response to infection. Expected outcomes include the discovery of new RBPs regulating immunity, with ....RNA-binding proteins rewire transcriptomes in immune cell differentiation. This project aims to combine advanced computational and experimental techniques to investigate a new layer of gene regulation by novel RNA binding proteins (RBP) which control messenger RNA length in immune cells. This project expects to demonstrate that these RBPs have a profound effect on immune cell differentiation and response to infection. Expected outcomes include the discovery of new RBPs regulating immunity, with mechanism and function determined by novel CRISPR editing of a transgenic mouse model. The significant benefit will be a more complete understanding of RNA mechanisms of immune response, which will be critical in informing future advances in the rapidly developing areas of RNA-based biotechnologies and synthetic immunology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100001
Funder
Australian Research Council
Funding Amount
$875,000.00
Summary
A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected out ....A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected outcomes to include the generation of new knowledge of major biological systems, including the immune system and the nervous system. This will provide significant benefits to fundamental interdisciplinary research into immunology, infectious disease, neuroscience, mechanobiology and engineering.Read moreRead less
Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing an ....Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing and reduced-order state observer, supported by lab/plant experiments, and collaborating with two industry partners from coal and steel industries. The project outcomes including codes, models and raceway control strategies can help promote Australian metallurgical coal's global markets and ultimately the Australian economy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100131
Funder
Australian Research Council
Funding Amount
$539,000.00
Summary
Federated Omniverse Facilities for Smart Digital Futures. A world-first trans-disciplinary, -domain, and -institutional smart 3D omniverse R&D ecosystem AuVerse will be built in NSW, affiliated with Queensland, and accessible to academia and industry. AuVerse will support cloud-based, reality-virtuality-fused, immersive, interactive and secure future-oriented digital design, development, training and society. In the new era of digital innovation and paradigm shift, AuVerse will substantially boo ....Federated Omniverse Facilities for Smart Digital Futures. A world-first trans-disciplinary, -domain, and -institutional smart 3D omniverse R&D ecosystem AuVerse will be built in NSW, affiliated with Queensland, and accessible to academia and industry. AuVerse will support cloud-based, reality-virtuality-fused, immersive, interactive and secure future-oriented digital design, development, training and society. In the new era of digital innovation and paradigm shift, AuVerse will substantially boost Australia’s pivotal research leadership and business competitiveness in nurturing new-generation, collaborative and transformative digital R&D and talent pipeline. It will enable large-scale strategic business innovation and transformation including smart manufacturing and Industry 4.0.Read moreRead less
Expectations and commitments in the Australia-USA alliance. This project aims to investigate the gap between the high expectations of mutual support and the lack of detailed security commitments in the Australia-US Alliance. The project intends to use a focused approach that captures thematic aspects of the alliance through project frames and historical slices across time. Expected outcomes can advance understanding of how alliances operate as security institutions. The outcomes can help to prom ....Expectations and commitments in the Australia-USA alliance. This project aims to investigate the gap between the high expectations of mutual support and the lack of detailed security commitments in the Australia-US Alliance. The project intends to use a focused approach that captures thematic aspects of the alliance through project frames and historical slices across time. Expected outcomes can advance understanding of how alliances operate as security institutions. The outcomes can help to promote a more informed national conversation about the costs and benefits of Australia's security relationship with the United States of America (USA) and contribute to debates over the future of the Australia-USA Alliance during a period of strategic uncertainty.Read moreRead less
New Lead-Free Brass Solutions for Drinking Water Applications. The aim of this Linkage Project is to provide viable material solutions to address the health problem of Lead-contamination in drinking water arising from Leaded-brass plumbing products and the impact Lead-removal from brass will have on the brass industry. In order to achieve this, this project engages leading multidisciplinary researchers along with Australian and international industry partners from across the brass industry suppl ....New Lead-Free Brass Solutions for Drinking Water Applications. The aim of this Linkage Project is to provide viable material solutions to address the health problem of Lead-contamination in drinking water arising from Leaded-brass plumbing products and the impact Lead-removal from brass will have on the brass industry. In order to achieve this, this project engages leading multidisciplinary researchers along with Australian and international industry partners from across the brass industry supply and sales network. This project seeks to identify and harness the key material-product attributes required to develop and implement new, lead-free alloy alternatives that meet health-compliance, production and commercial viability, that offer benefits across the industry network and health benefits to society.Read moreRead less
Special Research Initiatives - Grant ID: SR200200739
Funder
Australian Research Council
Funding Amount
$202,156.00
Summary
Monitoring Deliberative Integrity in Australia. The project aims to develop and apply the concept of deliberative integrity as a counterpart to more familiar ideas about electoral integrity in the evaluation of democratic processes. The project develops significant new knowledge about the ethical conduct of Australian citizen engagement processes through conceptual and methodological innovation to produce a Deliberative Integrity Monitoring Tool that will be applied to the expanding range of del ....Monitoring Deliberative Integrity in Australia. The project aims to develop and apply the concept of deliberative integrity as a counterpart to more familiar ideas about electoral integrity in the evaluation of democratic processes. The project develops significant new knowledge about the ethical conduct of Australian citizen engagement processes through conceptual and methodological innovation to produce a Deliberative Integrity Monitoring Tool that will be applied to the expanding range of deliberative democratic innovations in Australia. Expected outcomes include a better understanding of how such innovations can and should be designed. Benefits include a set of standards for best practice in democratic innovation that will in turn help improve the quality of Australian democracy.Read moreRead less
WRL Communication, Education And Engagement Program
Funder
Fisheries Research and Development Corporation
Funding Amount
$750,000.00
Summary
The Western Rock Lobster Council’s (WRLC) Strategic Plan defines the organisation’s purpose as providing the community with the economic and social benefits of a sustainable western rock lobster industry supplying its iconic product to local and overseas markets.
It outlines a vision for industry to have the full confidence of government, the community, and members as a well-resourced, self-funded peak body engaged in advocacy and co-management for improved resource security.
O ....The Western Rock Lobster Council’s (WRLC) Strategic Plan defines the organisation’s purpose as providing the community with the economic and social benefits of a sustainable western rock lobster industry supplying its iconic product to local and overseas markets.
It outlines a vision for industry to have the full confidence of government, the community, and members as a well-resourced, self-funded peak body engaged in advocacy and co-management for improved resource security.
One of the key actions outlined in the Strategic Plan under the fourth key objective ‘Ensure the social licence to operate is supported by government, community and industry’ is to develop and implement a revised communications strategy for members, stakeholders, and the community.
While the indications for achieving social licence for the western rock lobster industry are currently positive, consolidating and increasing that support depends on the evolving social and political landscape. Building on the on innovation and lessons learnt during the execution of the previous Communication Program 2020-058, and through the development and application of more mature initiatives drawn out from its updated Communication and Engagement Strategy, the industry will strengthen its connection to the community, continue to increase support from key stakeholders and the general public, and consolidate its Social Licence to operate. This Program application delivers on that commitment. Objectives: 1. Strengthen industry members' engagement: Increase the full participation by internal stakeholders in Council activities, to best enable the Council to represent the industry to government and other stakeholders. This includes industry engagement and communication of WRL IPA activities and R&D outputs. 2. Broaden and deepen relationships with external stakeholders from government and other industries to make the Council and the industry more resilient. 3. Build awareness of the significant contribution the industry continues to make to coastal communities, and the state. 4. Increase community awareness of the availability and accessibility of western rock lobster. 5. Ensure the industry is getting maximum social license benefits from its Marine Stewardship Council certification as a sustainable fishery. Read moreRead less