EGF Peptide Signalling Improves Oocyte Maturation And Quality
Funder
National Health and Medical Research Council
Funding Amount
$586,891.00
Summary
Infertility is common and although IVF is widely accepted, the procedure is expensive and is associated with health risks. Using laboratory animals, we have developed significant new insights into mechanisms regulating egg quality. These insights have allowed us to develop a new approach to infertility treatment - crucially, one that eliminates the need for ovarian hormone therapy used in IVF. This project will investigate the basic mechanisms underlying our new approach to enable safe clinical ....Infertility is common and although IVF is widely accepted, the procedure is expensive and is associated with health risks. Using laboratory animals, we have developed significant new insights into mechanisms regulating egg quality. These insights have allowed us to develop a new approach to infertility treatment - crucially, one that eliminates the need for ovarian hormone therapy used in IVF. This project will investigate the basic mechanisms underlying our new approach to enable safe clinical implementation.Read moreRead less
Infertility is common and although IVF is widely accepted, the procedure is expensive and is associated with health risks. Using laboratory animals, we have made significant advances towards developing new technologies that can mature eggs and produce embryos in vitro, but without women receiving hormone injections. This project will seek means to combine the benefits of two of our existing technologies into one integrated system, to provide hormone-free infertility treatment.
Integrating choice set formation and taste heterogeneity in market segmentation. This project develops a new model of consumer decision-making to provide managerial insights related to market segmentation, product portfolio optimisation and marketing communication strategies. The model can be specified for a particular product category using data collected from a novel elicitation instrument developed as part of this project.
A process model of visual working memory. This project aims to develop a process model of encoding of items into memory. Working memory is central to almost all cognitive functions, but little is known about short-term memory for visual information. Progress in this area is slow because of a focus on models that do not specify the processes underlying memory, and no model explains the processes that would limit the number of items the memory can hold to four. A process model is expected to addre ....A process model of visual working memory. This project aims to develop a process model of encoding of items into memory. Working memory is central to almost all cognitive functions, but little is known about short-term memory for visual information. Progress in this area is slow because of a focus on models that do not specify the processes underlying memory, and no model explains the processes that would limit the number of items the memory can hold to four. A process model is expected to address fundamental issues in visual working memory.Read moreRead less
Towards an integrated model of reasoning and reasoning development. This project aims to identify the core cognitive processes that underlie different forms of reasoning and how they develop. The project intends to use a signal detection framework to derive detailed computational models of reasoning which can then be tested through Bayesian computational modelling as well as the first systematic investigation of developmental change in reasoning processes. Expected outcomes include a more princi ....Towards an integrated model of reasoning and reasoning development. This project aims to identify the core cognitive processes that underlie different forms of reasoning and how they develop. The project intends to use a signal detection framework to derive detailed computational models of reasoning which can then be tested through Bayesian computational modelling as well as the first systematic investigation of developmental change in reasoning processes. Expected outcomes include a more principled and comprehensive computational model of reasoning in both adults and children. The project should provide significant benefits by helping to resolve long-standing debates about how humans reason complex arguments relevant to everyday lives and guide development of more effective methods for teaching reasoning.Read moreRead less
Uncovering the processes underlying human reasoning: A state-trace approach. This project aims to answer the most important unresolved question in the psychology of reasoning; how many distinct cognitive processes underlie human reasoning? To answer this question, this project aims to conduct an extensive experimental investigation of the factors that selectively impact inductive and deductive inferences and the application of high-dimensional state-trace analysis; a powerful new method for diag ....Uncovering the processes underlying human reasoning: A state-trace approach. This project aims to answer the most important unresolved question in the psychology of reasoning; how many distinct cognitive processes underlie human reasoning? To answer this question, this project aims to conduct an extensive experimental investigation of the factors that selectively impact inductive and deductive inferences and the application of high-dimensional state-trace analysis; a powerful new method for diagnosing underlying processes from behavioural data. The project is expected also to develop a new computational model that accounts for both inductive and deductive forms of reasoning.Read moreRead less
State-trace analysis: theory and application. A fundamental question for the science of psychology is: how can we identify the functional components of the human mind from observed behaviour and bodily states? This project explores this question through a new methodology called state-trace analysis and apply it to a basic cognitive ability - the capacity to learn to classify different objects.
Information Seeking & Research Adoption: Assessing Communication Strategies. This project aims to determine the best ways to communicate wine research and to design tools to support research adoption. Adoption of research relies on effective use of information and technology by employees. Research into employees’ information practices in the workplace has been conducted in health care, education and other areas; however, the wine industry’s use of information and technology for adoption is unexp ....Information Seeking & Research Adoption: Assessing Communication Strategies. This project aims to determine the best ways to communicate wine research and to design tools to support research adoption. Adoption of research relies on effective use of information and technology by employees. Research into employees’ information practices in the workplace has been conducted in health care, education and other areas; however, the wine industry’s use of information and technology for adoption is unexplored. The project plans to assess the strategies used to share research with winemakers and grape growers (e.g. seminars, websites, social media), from information behaviour or web useability perspectives, to ensure industry needs are met appropriately. This research aims to have a direct and immediate impact on the wine industry. In addition to the immediate impact of new research innovations that will be implemented by our partner wine companies, the project will also change industry-wide approaches to extension. The partner organisations use extension strategies to showcase new innovations and our research will assess these organisations’ current practices, providing evidence to shape the design of future activities in Australia.Read moreRead less
Are two processes one too many? An investigation of the viability of the dual-process model of recognition memory. Memory is the glue that holds together our lives and personal identities. While psychologists are developing better and more sophisticated accounts of how it works, many deep questions remain. The present research examines some of these questions in relation to how memory can be decomposed into its component processes and how we are to understand these processes. An appropriate unde ....Are two processes one too many? An investigation of the viability of the dual-process model of recognition memory. Memory is the glue that holds together our lives and personal identities. While psychologists are developing better and more sophisticated accounts of how it works, many deep questions remain. The present research examines some of these questions in relation to how memory can be decomposed into its component processes and how we are to understand these processes. An appropriate understanding of these questions is vital to the development of interventions (both psychological and pharmacological) designed to halt or even reverse memory decline associated with normal aging and age-associated brain disease (such as Alzheimer disease).Read moreRead less
The role of online social networks in successful ageing: benefitting from 'who you know' at older ages. The project will increase understanding of how online social networking contributes to successful ageing through partnering, economic and voluntary activity, family and social connectedness. The findings will inform policy recommendations, social interventions and education programs designed to enhance 'ageing well, ageing productively'. These are expected to benefit the health and well-being ....The role of online social networks in successful ageing: benefitting from 'who you know' at older ages. The project will increase understanding of how online social networking contributes to successful ageing through partnering, economic and voluntary activity, family and social connectedness. The findings will inform policy recommendations, social interventions and education programs designed to enhance 'ageing well, ageing productively'. These are expected to benefit the health and well-being of older Australians, with economic benefits of increased contributions to society and fewer demands on services. Social and economic benefits are also expected from insights into reducing the technological and psychological barriers that prevent older people from benefiting from the Internet and online social networking.Read moreRead less