Intracellular manufacturing - high performance biomaterials from methane. The aim of this project is to produce high performance biodegradable polymers directly from methane. The key innovation is employing cutting-edge community genomic and transcriptomic approaches to characterise intracellular production lines in order to tailor polyhydroxybutyrate-co-valerate (PHBV) copolymer microstructures. This is a truly multidisciplinary project bringing together engineers, polymer scientists and molecu ....Intracellular manufacturing - high performance biomaterials from methane. The aim of this project is to produce high performance biodegradable polymers directly from methane. The key innovation is employing cutting-edge community genomic and transcriptomic approaches to characterise intracellular production lines in order to tailor polyhydroxybutyrate-co-valerate (PHBV) copolymer microstructures. This is a truly multidisciplinary project bringing together engineers, polymer scientists and molecular biologists. It is expected that a direct outcome of the project will be the first PHBV copolymer from methane. As such, the project aims to develop technology for the production of tough, flexible and affordable biopolymers and, at the same time, provide an opportunity to add value to methane.Read moreRead less
The micro-mechanical origins of creep in granular materials. Creep in granular materials is a concern for many problems in technology and science, including long-term deformations of reservoir dams and sudden instabilities along earthquake faults. This project aims to describe the fine-scale origins of granular creep, as a basis for solving problems of much larger-scale in geomechanics and geophysics.
Scaling microfluidics for cell manufacture. Scaling microfluidics for cell manufacture. This project aims to scale microfluidic devices for cell manufacture. Large-scale cell manufacturing processes (cell selection, gene transfer and culture expansion) are expensive, multistep and labour-intensive processes. Lab-on-a-chip devices can automate and integrate these complex processes at microscale. This project will evaluate a prototype bioreactor. This research is expected to make cell therapies ch ....Scaling microfluidics for cell manufacture. Scaling microfluidics for cell manufacture. This project aims to scale microfluidic devices for cell manufacture. Large-scale cell manufacturing processes (cell selection, gene transfer and culture expansion) are expensive, multistep and labour-intensive processes. Lab-on-a-chip devices can automate and integrate these complex processes at microscale. This project will evaluate a prototype bioreactor. This research is expected to make cell therapies cheap enough to become standard treatment, which would benefit patients with diseases that are incurable by conventional therapies (surgery and drug treatments). It should also benefit the Australian advanced manufacturing sector, particularly biopharmaceutical and cell therapy industries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101402
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Advanced laser micromachining with femtosecond vector beams. This project is aimed at developing a new method for ultra-precision laser micromachining and dissection of biological tissues using femtosecond vector beams. The capability of these unconventional laser beams to process different materials with unsurpassed precision and efficiency offers significant economic and clinical benefits.
Fault tolerant control based on set-theoretic methods: robustness, nonlinear effects and probabilistic developments. This project will bring benefits to Australia by developing innovative self-healing technological systems that are able to maintain appropriate levels of performance while reacting to unforeseeable faults. The project will contribute to the National Research Priority area: Frontier Technologies for Building and Transforming Australian Industries.
Particle segregation and dynamics in inertial microfluidics systems. This project aims to produce microfluidic devices suitable for high-throughput cell sorting and cellular therapy in the biopharmaceutical industry. This project will combine state-of-the-art experimental approaches with advanced modelling techniques to design and develop the new generation of filtration systems for the pharmaceutical industry. The knowledge and models developed in this project will assist design and development ....Particle segregation and dynamics in inertial microfluidics systems. This project aims to produce microfluidic devices suitable for high-throughput cell sorting and cellular therapy in the biopharmaceutical industry. This project will combine state-of-the-art experimental approaches with advanced modelling techniques to design and develop the new generation of filtration systems for the pharmaceutical industry. The knowledge and models developed in this project will assist design and development of a unique platform for scalable, high-throughput, low-cost and continuous cell separation.Read moreRead less
Biosolid flow, separation and activity in anaerobic lagoons. This project aims to develop a fundamental model of the complex, non-steady state flow behaviour in anaerobic lagoons. The project will develop new operating procedures and designs for large municipal, industrial and agricultural anaerobic lagoons. This will improve the efficiency of anaerobic digestion and reduce wastewater treatment costs, as well as increase renewable and sustainable biogas production. The intended outcome is a va ....Biosolid flow, separation and activity in anaerobic lagoons. This project aims to develop a fundamental model of the complex, non-steady state flow behaviour in anaerobic lagoons. The project will develop new operating procedures and designs for large municipal, industrial and agricultural anaerobic lagoons. This will improve the efficiency of anaerobic digestion and reduce wastewater treatment costs, as well as increase renewable and sustainable biogas production. The intended outcome is a validated 3D model that captures the physical and biological complexities of anaerobic lagoons. This will impact the design and operation of partner organisation lagoons, reducing capital and operating costs and improving biogas production.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140100569
Funder
Australian Research Council
Funding Amount
$372,952.00
Summary
Recovering helium from Australia’s natural gas: A case study for advanced adsorption processes to concentrate dilute gases. This project will deliver breakthroughs in gas separation technologies for the production of helium from natural gas. Global demand for helium in critical medical, scientific and industrial applications is projected to grow at around five per cent per annum. To overcome the forecast short falls in helium production, new low cost and energy efficient technologies to recover ....Recovering helium from Australia’s natural gas: A case study for advanced adsorption processes to concentrate dilute gases. This project will deliver breakthroughs in gas separation technologies for the production of helium from natural gas. Global demand for helium in critical medical, scientific and industrial applications is projected to grow at around five per cent per annum. To overcome the forecast short falls in helium production, new low cost and energy efficient technologies to recover helium from natural gas fields must be developed. This project will contribute novel microporous adsorbents, a better understanding of helium sorption kinetics and general methodologies for design of pressure swing adsorption processes to concentrate dilute mixtures.Read moreRead less
Optimised flush repairs for dissimilar composite material systems. The outcome of this research project will overcome a major technological challenge when designing repairs for dissimilar composite material systems, which are being utilised at an increasing pace in a multitude of industries. This new technological capability will help to improve the competitiveness of the Australian aerospace industry.
Catastrophic transition to turbulence in rotation-dominated flows. Rotation-dominated flows are very common in engineering applications and fluid dynamics of the Earth's atmosphere, oceans, and core. Such flows are known to make a sudden transition from an orderly to an energetic turbulent state and this project aims to discover the reason why.