The response of mitochondria to oxidative stress in plants. Crops encounter many situations in their environment which place them under stress. Reactive oxygen molecules produced in these situations act as messengers to trigger defence mechanisms but also cause cellular damage. Mitochondria are the subcellular compartments involved in energy production and are essential for plant development and growth. However, they also have been implicated in the response of plants to stress and pathogen atta ....The response of mitochondria to oxidative stress in plants. Crops encounter many situations in their environment which place them under stress. Reactive oxygen molecules produced in these situations act as messengers to trigger defence mechanisms but also cause cellular damage. Mitochondria are the subcellular compartments involved in energy production and are essential for plant development and growth. However, they also have been implicated in the response of plants to stress and pathogen attack, and in production of reactive oxygen molecules. This proposal seeks to investigate how mitochondria are involved in these processes, focusing on the role of terminal oxidases. Potential outcomes include crops better able to cope with environmental stress.Read moreRead less
Why are many fungicide lead compounds active against pathogens in axenic culture but inactive when applied to infected plants? It is much cheaper and easier to screen compounds for fungicidal activity in vivo (that is against the fungus grown in axenic culture) than to test in planta. However, it is commonly observed that compounds active in in vivo screens do not subsequently prove to be active in planta. The aim of this project is to investigate the physiological, biochemical and genetics basi ....Why are many fungicide lead compounds active against pathogens in axenic culture but inactive when applied to infected plants? It is much cheaper and easier to screen compounds for fungicidal activity in vivo (that is against the fungus grown in axenic culture) than to test in planta. However, it is commonly observed that compounds active in in vivo screens do not subsequently prove to be active in planta. The aim of this project is to investigate the physiological, biochemical and genetics basis of this discrepancy and to attempt to provide tools that circumvent the problem. It is expected the project will generate novel information on the environment in the plant experienced by the fungus.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347922
Funder
Australian Research Council
Funding Amount
$630,000.00
Summary
Joint Facility for Plant Genetic Analysis and Gene Discovery in WA. This project will extend collaboration between Murdoch and UWA by provision of advanced facilities for plant genetic analysis and gene discovery. This will be achieved by purchase of novel equipment for discovery and analysis of single nucleotide polymorphisms (SNPs - single base changes between individual plants) that mark differences in their properties, and by purchase of equipment to underpin gene discovery and analysis of ....Joint Facility for Plant Genetic Analysis and Gene Discovery in WA. This project will extend collaboration between Murdoch and UWA by provision of advanced facilities for plant genetic analysis and gene discovery. This will be achieved by purchase of novel equipment for discovery and analysis of single nucleotide polymorphisms (SNPs - single base changes between individual plants) that mark differences in their properties, and by purchase of equipment to underpin gene discovery and analysis of expression. Provision of this equipment will enable full use of plant growth facilities now under construction, lead to advanced technologies of plant genetic analysis, and discovery of new basic information on fundamental plant processes.Read moreRead less
Enhancement of monopartite geminivirus pathogenicity by satellite DNA beta encoded betaC1 protein: the role of host factors. Australian incursions of geminiviruses are uncontrollable due to their unique mode of spread by whiteflies. The first incursion in Darwin in 1970 has spread to Far Northern Queensland. The second in SE Queensland in 2006 is estimated to cause $500 million loss to horticulture. Our $2 billion cotton industry is threatened by cotton leaf curl diseases from South Asia, where ....Enhancement of monopartite geminivirus pathogenicity by satellite DNA beta encoded betaC1 protein: the role of host factors. Australian incursions of geminiviruses are uncontrollable due to their unique mode of spread by whiteflies. The first incursion in Darwin in 1970 has spread to Far Northern Queensland. The second in SE Queensland in 2006 is estimated to cause $500 million loss to horticulture. Our $2 billion cotton industry is threatened by cotton leaf curl diseases from South Asia, where DNA beta enhances virus replication and disease severity. DNA beta has the potential to enter Australia with several different geminiviruses and to spread into others by co-infection, which requires research on detection and pathogenesis of DNA beta.Read moreRead less
The Other Side: Long-distance Feedback and Cross-talk in the Arabidopsis Branching Gene Network. Shoot structure in nearly all plants impacts on water relations, yield and sustainability. Isolation of novel genes and plant hormone pathways that affect shoot structure should allow us to capture IP for Australia and enhance plant improvement and sustainability. One of the pathways we will investigate produces glucosinolates, small plant-specific molecules that have considerable value as anti-cance ....The Other Side: Long-distance Feedback and Cross-talk in the Arabidopsis Branching Gene Network. Shoot structure in nearly all plants impacts on water relations, yield and sustainability. Isolation of novel genes and plant hormone pathways that affect shoot structure should allow us to capture IP for Australia and enhance plant improvement and sustainability. One of the pathways we will investigate produces glucosinolates, small plant-specific molecules that have considerable value as anti-cancer agents in humans. Flavonoids, another pathway regulated in our shoot branching lines, also benefit human health. Graduate students and postdoctoral researchers will gain skills in research management, design, ethics and experimental methods pertinent to the growing biotechnology industry in Australia.Read moreRead less
Accelerated Domestication of Australian Grass Species Using Molecular Tools. The development of new food crops from the Australian flora will provide opportunities for new sustainable agricultural and food industries in Australia. The project targets the accelerated domestication of native species with lower tillage and fertiliser requirements, better water use efficiencies and increased salt, shade, frost and/or drought tolerances than the current introduced cereal and fodder crops. This will ....Accelerated Domestication of Australian Grass Species Using Molecular Tools. The development of new food crops from the Australian flora will provide opportunities for new sustainable agricultural and food industries in Australia. The project targets the accelerated domestication of native species with lower tillage and fertiliser requirements, better water use efficiencies and increased salt, shade, frost and/or drought tolerances than the current introduced cereal and fodder crops. This will directly benefit regional Australia. The technologies developed in the project will have wide application to accelerated domestication of other Australian plants (for agriculture and food production in Australia and internationally) and to plants found in other parts of the world.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989351
Funder
Australian Research Council
Funding Amount
$425,000.00
Summary
High Resolution Mass Spectrometry Facility. The research that will be supported by this vital infrastructure impacts on the sustainable environment through understanding the process of seed germination and the human condition through new drugs for the treatment of cancer and Parkinson's disease. Fundamental science will also be addressed particularly in the fields of photonics and the nature of interactions between matter.
The Development of Microbial Inoculants as Biofertilisers for Rice, Wheat and Turf-Grass. Plant-microbial interactions can increase vegetative growth and crop yield. These PGPR effects result from improved N and P nutrition, stimulation of root growth, disease control, altered environmental conditions and, most importantly, positive interactions between all these. This project aims to develop plant growth promoting bacteria and fungi as commercial products. By matching microbes to plants and soi ....The Development of Microbial Inoculants as Biofertilisers for Rice, Wheat and Turf-Grass. Plant-microbial interactions can increase vegetative growth and crop yield. These PGPR effects result from improved N and P nutrition, stimulation of root growth, disease control, altered environmental conditions and, most importantly, positive interactions between all these. This project aims to develop plant growth promoting bacteria and fungi as commercial products. By matching microbes to plants and soil environments, a set of peat-based inoculants will be optimised for application as biofertilisers to field crops and turfgrass.
Potential applications are both rural and urban.
The outcomes will be proven commercial products able to promote plant growth and rapid recovery from adverse conditions.Read moreRead less
Evolution of halophytes: a phyloinformatic approach to understanding and exploiting the traits underlying salt-tolerance in plants. Salinity is an increasing burden on the Australian economy & environment, with >2 million ha of salt-affected land, at an annual cost to agriculture over $187 million. One solution is to exploit naturally salt-tolerant plants to increase productive agricultural land and restore salt-affected environments. To do this, we must increase basic knowledge of the diversity ....Evolution of halophytes: a phyloinformatic approach to understanding and exploiting the traits underlying salt-tolerance in plants. Salinity is an increasing burden on the Australian economy & environment, with >2 million ha of salt-affected land, at an annual cost to agriculture over $187 million. One solution is to exploit naturally salt-tolerant plants to increase productive agricultural land and restore salt-affected environments. To do this, we must increase basic knowledge of the diversity & distribution of salt-tolerance. This project is the first to use DNA sequences from thousands of species to understand the evolution of salt-tolerance in order to provide the foundation for the development of new crop varieties, selection of species that can be developed for bioremediation, and identification of traits that will be profitable targets for breeding programs. Read moreRead less
In-Vitro Production of Baculovirus Biopesticides - A Systems Biology Approach. This project has the potential to develop an in-vitro production process that can produce large quantities of Baculoviruses at costs comparable to selective chemicals. This could transform agriculture allowing farmers to choose an insect control option that is both safe and efficacious to use as well as economically and environmentally superior to chemicals, and less controversial than transgenic plants. This outcome ....In-Vitro Production of Baculovirus Biopesticides - A Systems Biology Approach. This project has the potential to develop an in-vitro production process that can produce large quantities of Baculoviruses at costs comparable to selective chemicals. This could transform agriculture allowing farmers to choose an insect control option that is both safe and efficacious to use as well as economically and environmentally superior to chemicals, and less controversial than transgenic plants. This outcome would enhance Australia's reputation in the animal cell technology field (related technology is used to produce protein pharmaceutical products), and will earn significant export dollars through licensing out of the technology or through large scale manufacturing and export of the product itself. Read moreRead less