Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100036
Funder
Australian Research Council
Funding Amount
$310,000.00
Summary
Super high speed grinding facility for difficult-to-machine materials and structures. This unique system will enable the manufacture of difficult-to-machine materials and structures with high quality and high productivity. It will support ground-breaking research activities across the country and help promote the strategic collaborations within Australian manufacturing society.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100016
Funder
Australian Research Council
Funding Amount
$490,000.00
Summary
Multi-scale fabrication facility for complex three-dimensional surface generation from nano to macro dimensions. This facility will support advances in the manufacturing of free-form surfaces with submicron features. Its unique characteristics, such as the universal profiling ability and nanometre accuracy across large dimensions, will enable many science and engineering innovations which are presently impossible to be realised in Australia.
Developing orthogonal synthetic signaling cascades. This project proposes a generic approach for the construction of molecular switches based on artificially autoinhibited proteases. The bottom-up design of protein-based signaling networks is a key goal of synthetic biology. Yet, this remains elusive due to our inability to tailor-make signal transducers and receptors that can be readily compiled into defined signaling networks. Using structure-guided design and directed protein evolution, a set ....Developing orthogonal synthetic signaling cascades. This project proposes a generic approach for the construction of molecular switches based on artificially autoinhibited proteases. The bottom-up design of protein-based signaling networks is a key goal of synthetic biology. Yet, this remains elusive due to our inability to tailor-make signal transducers and receptors that can be readily compiled into defined signaling networks. Using structure-guided design and directed protein evolution, a set of protease-based signal transducers and ligand activated allosteric receptors will be created. The developed components are intended to be used to construct artificial signaling networks in mammalian cells that are orthogonal to the endogenous signaling cascades.Read moreRead less
Microwave Detection of Structural Degradation in Maritime Industry. Novel applications of microwave technology to inspection systems in marine infrastructure will transform industry practice. By utilizing multi-mode antennas, the project aims to develop a gold-standard in microwave inspection, delivering more accurate and early detection of defects. The project aims will be achieved by combining innovative microwave technology, featuring multi-mode antennas and novel processing and imaging algor ....Microwave Detection of Structural Degradation in Maritime Industry. Novel applications of microwave technology to inspection systems in marine infrastructure will transform industry practice. By utilizing multi-mode antennas, the project aims to develop a gold-standard in microwave inspection, delivering more accurate and early detection of defects. The project aims will be achieved by combining innovative microwave technology, featuring multi-mode antennas and novel processing and imaging algorithms, with ground-breaking smart scanning and unmanned marine vehicle implementations. This innovative outcome obviates the need for current industry approaches based on inaccurate and tedious manual inspections, yielding massive cost savings and reductions in hazard associated with unanticipated structural failure.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100126
Funder
Australian Research Council
Funding Amount
$527,638.00
Summary
Advanced Maskless Photolitography for Western Australia. This project aims to close an existing gap in micro- & nano-fabrication in Western Australia and provide access to advanced maskless photolithography in support of Australian research flagships of international excellence which include advanced infrared and quantum technologies, semiconductor optoelectronics, chemical engineering, microelectromechanical systems, as well as dark matter and gravitational wave discovery. Notably, the new capa ....Advanced Maskless Photolitography for Western Australia. This project aims to close an existing gap in micro- & nano-fabrication in Western Australia and provide access to advanced maskless photolithography in support of Australian research flagships of international excellence which include advanced infrared and quantum technologies, semiconductor optoelectronics, chemical engineering, microelectromechanical systems, as well as dark matter and gravitational wave discovery. Notably, the new capability is of utmost importance for five distinct ARC Centres in multidisciplinary areas and will be available to all researchers via the WA Node of Australian National Fabrication Facility in support of high impact scientific research and to maintain strong engagement with industry and Australian economy.Read moreRead less
Special Research Initiatives - Grant ID: SR0354630
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Fluorescence Applications in Biotechnology and Life Sciences. The Network in Fluorescence applications in biotechnology and life sciences will coordinate a research program relating to applications of fluorescence whose proper resolution requires a high degree of interaction between biology, physics, chemistry, bioengineering and medicine. These would be applied to industrially relevant problems in areas such as public health, biotechnology, safety of foods, chemical biology and environmental mo ....Fluorescence Applications in Biotechnology and Life Sciences. The Network in Fluorescence applications in biotechnology and life sciences will coordinate a research program relating to applications of fluorescence whose proper resolution requires a high degree of interaction between biology, physics, chemistry, bioengineering and medicine. These would be applied to industrially relevant problems in areas such as public health, biotechnology, safety of foods, chemical biology and environmental monitoring. Approaches such as highly selective fluorescent labelling of targets using appropriate immunological and molecular techniques and purpose-engineered fluorochromes accompanied by the development of specialised instrumentation will capitalise on the multi-disciplinary research strengths in Australia and lead towards tangible industrial outcomes.
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ARC/NHMRC Research Network Fluorescence Applications in Biotechnology and Life Sciences. This Network will concentrate Australian research in new applications of fluorescence to biological systems to solve significant problems in health diagnostics, biotechnology and the environment. The scientific goals identified by the Network such as highly selective fluorescent labelling and purpose-engineered fluorochromes will be accompanied by the development of specialised instrumentation. These resear ....ARC/NHMRC Research Network Fluorescence Applications in Biotechnology and Life Sciences. This Network will concentrate Australian research in new applications of fluorescence to biological systems to solve significant problems in health diagnostics, biotechnology and the environment. The scientific goals identified by the Network such as highly selective fluorescent labelling and purpose-engineered fluorochromes will be accompanied by the development of specialised instrumentation. These research directions pursued by strong multi-disciplinary teams spanning biology, chemistry, physics, bioengineering and medicine will benefit from the support of the Network programs. Through its focus on academic - industry collaboration the Network will also facilitate development of basic scientific discoveries into commercial outcomes.Read moreRead less
Rotating Radiofrequency Phased-array for 7 Tesla Magnetic Resonance Imaging. This project aims to develop a new type of radiofrequency coil array to ensure high-field magnetic resonance imaging (MRI), with all its benefits, is available for a broader range of applications. High-field MRI offers faster scans with more detailed images than lower field systems. This enhanced sensitivity potentially enables smaller structures to be resolved in the body. At high fields, however, standard radiofrequen ....Rotating Radiofrequency Phased-array for 7 Tesla Magnetic Resonance Imaging. This project aims to develop a new type of radiofrequency coil array to ensure high-field magnetic resonance imaging (MRI), with all its benefits, is available for a broader range of applications. High-field MRI offers faster scans with more detailed images than lower field systems. This enhanced sensitivity potentially enables smaller structures to be resolved in the body. At high fields, however, standard radiofrequency coils, an essential component of MRI systems, can distort images and induce potentially harmful tissue heating. The aim is to design and develop a rotating multi-channel radiofrequency coil array, with dedicated image reconstruction software, to overcome these limitations. This would facilitate detailed images that can be obtained quickly and safely.Read moreRead less
Nanoparticle driven templating of microspheres as chromatographic materials. This project aims to pioneer a novel, high-performing class of nano-patterned core-shell particles as chromatographic materials. It will use advanced polymerization and particle preparation techniques in combination with degradable nanoparticles design, to enable the plug-and-play assembly of chromatographic columns. Size-exclusion chromatography (SEC) is one of the most important analytical techniques for polymer chem ....Nanoparticle driven templating of microspheres as chromatographic materials. This project aims to pioneer a novel, high-performing class of nano-patterned core-shell particles as chromatographic materials. It will use advanced polymerization and particle preparation techniques in combination with degradable nanoparticles design, to enable the plug-and-play assembly of chromatographic columns. Size-exclusion chromatography (SEC) is one of the most important analytical techniques for polymer chemistry. The expected outcomes of this project are faster measurement times and the possibility of imaging molecular weight distributions at a new level of detail. This project could place Australia at the cutting edge of size-exclusion chromatography phase design in partnership with a leading manufacturer of stationary phases.Read moreRead less
Silicon-germanium-carbon - a novel opto-mechanic material for optical micro-electromechanical systems. Evolving from past black-and-white images, through present red-green-blue multi-spectral capability, future remote imaging systems promise spectroscopic functionality across much broader wavelength ranges in a low-cost system. However, the high cost of multiple materials and technologies for each specific spectral band limits them to high-cost industry sectors. This project proposes a simple, l ....Silicon-germanium-carbon - a novel opto-mechanic material for optical micro-electromechanical systems. Evolving from past black-and-white images, through present red-green-blue multi-spectral capability, future remote imaging systems promise spectroscopic functionality across much broader wavelength ranges in a low-cost system. However, the high cost of multiple materials and technologies for each specific spectral band limits them to high-cost industry sectors. This project proposes a simple, low-cost, single material technology based on silicon-germanium-carbon thin films for mechanical and optical applications from ultraviolet to long-wave infrared, enabling widespread application of spectroscopic imaging to multiple fields extending from climate change research, through resource exploration, to cancer detection, and aerospace/defense.Read moreRead less