DROP DEFORMATION IN CONFINED MICROFLUIDIC GEOMETRIES. Increasingly, high technology applications in biotechnology and microtechnology industries need to process complex (non-Newtonian) fluids with dispersed particles/droplets in channels as small as several microns (microfluidics). A computational fluid dynamic model of non-Newtonian droplet deformation in microfluidic geometries will be developed, and validated using experimental measurements of the flow field in this project. The aim is to und ....DROP DEFORMATION IN CONFINED MICROFLUIDIC GEOMETRIES. Increasingly, high technology applications in biotechnology and microtechnology industries need to process complex (non-Newtonian) fluids with dispersed particles/droplets in channels as small as several microns (microfluidics). A computational fluid dynamic model of non-Newtonian droplet deformation in microfluidic geometries will be developed, and validated using experimental measurements of the flow field in this project. The aim is to understand and quantify factors influencing droplet deformation. Coupling non-Newtonian characteristics with microfluidic geometries will allow the continuous manufacture of micro-particles of specified size and shape for existing and new applications, and will provide guidance for further extending the process to nano-particle manufacture.Read moreRead less
Electro-viscous effects on pressure-driven liquid flow in microchannels. Australian biotechnology, information technology and food technology industries will benefit from the development of new tailored micro- and nano-fluidic devices for processing of non-Newtonian fluids. The efficiency of functional elements such as valves, pumps, mixers, reactors, heat exchangers can be optimised for specific fluids by understanding the coupling between the fluid properties, the device geometry, surface cha ....Electro-viscous effects on pressure-driven liquid flow in microchannels. Australian biotechnology, information technology and food technology industries will benefit from the development of new tailored micro- and nano-fluidic devices for processing of non-Newtonian fluids. The efficiency of functional elements such as valves, pumps, mixers, reactors, heat exchangers can be optimised for specific fluids by understanding the coupling between the fluid properties, the device geometry, surface charge, and the numerical predictions. This understanding will complement development in related projects on non-Newtonian drop and particle formation in microfluidic flows which envisage continuous particle manufacture for novel materials possessing programmable, enhanced functional properties.Read moreRead less
Micro Process Plants - Non-Newtonian flow and particle synthesis in confined geometries. Understanding the flow behaviour of well characterised non-Newtonian fluids within microfluidic and nanofluidic devices is of vital importance to development of novel high-value added services, products and devices within Australia's burgeoning biotechnology, environmental technology, communications and information technology industries. The outcomes of this project will provide new 'systematic' design stand ....Micro Process Plants - Non-Newtonian flow and particle synthesis in confined geometries. Understanding the flow behaviour of well characterised non-Newtonian fluids within microfluidic and nanofluidic devices is of vital importance to development of novel high-value added services, products and devices within Australia's burgeoning biotechnology, environmental technology, communications and information technology industries. The outcomes of this project will provide new 'systematic' design standards for microdevice manufacture for these industries, ultimately leading to the creation of new, exciting avenues for tailoring novel biotechnology and 'point-of-care' products for Australia.Read moreRead less
Simulating two-phase electrodynamic flows in droplet-based microfluidic circuit elements. The knowledge, data and analysis tools developed within this project will facilitate the economical production of electrodynamically controlled integrated droplet-based microfluidic devices for critical high-demand applications such as: genome sequencing; protein evolution, synthesis and crystallisation; micro-structured pharmaceuticals; disposable devices for biomedical analysis; portable point-of-entry (b ....Simulating two-phase electrodynamic flows in droplet-based microfluidic circuit elements. The knowledge, data and analysis tools developed within this project will facilitate the economical production of electrodynamically controlled integrated droplet-based microfluidic devices for critical high-demand applications such as: genome sequencing; protein evolution, synthesis and crystallisation; micro-structured pharmaceuticals; disposable devices for biomedical analysis; portable point-of-entry (biochem)security analysis devices. Hence this project is an investment in enabling technologies to benefit Australia's growing biotech, pharmaceutical and micro/nanotechnology sectors. Tangible community benefits (e.g., in improved diagnostic technologies, pharmaceuticals) will result.Read moreRead less
Resonant Nanostructures for Adaptive Optoelectronics. The science and technology outcomes of this project will create new, innovative solutions to current and future challenges facing industry, the community, and Australian national and strategic interests. Adaptive, resonant optoelectronics technologies will create new industries and enable, for the first time, advanced, low-cost, hand-held, spectroscopic systems for chemical/biological/process sensing for industries as diverse as food processi ....Resonant Nanostructures for Adaptive Optoelectronics. The science and technology outcomes of this project will create new, innovative solutions to current and future challenges facing industry, the community, and Australian national and strategic interests. Adaptive, resonant optoelectronics technologies will create new industries and enable, for the first time, advanced, low-cost, hand-held, spectroscopic systems for chemical/biological/process sensing for industries as diverse as food processing to pharmaceuticals manufacturing, portable biomedical diagnostics, and precision agriculture. The technologies will enhance Australia's ability to address defence and security needs related to surveillance, chemical/biological threat monitoring, border protection, and target identification.
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Lattice Boltzmann method based simulation of complex microchannels and mixing at micro-scales. The proposed study explores fundamental aspects of microfluidics using new tools, which will enhance the country's database of knowledge. It will lead to the development of a low-cost versatile software package, an important tool for solving microfluidics problems of interest to industries and academics, and will facilitate development and optimization of future microdevices. Further, it will improve A ....Lattice Boltzmann method based simulation of complex microchannels and mixing at micro-scales. The proposed study explores fundamental aspects of microfluidics using new tools, which will enhance the country's database of knowledge. It will lead to the development of a low-cost versatile software package, an important tool for solving microfluidics problems of interest to industries and academics, and will facilitate development and optimization of future microdevices. Further, it will improve Australia's competitiveness in the areas of LBM and MEMS both of which are new techniques with promising applications in their respective areas. The project falls under the National Research Priorities areas of Breakthrough Science and Frontier Technology. The potential applications of the technology encompass several key areas.Read moreRead less
Analysis, Optimization, and Control of Scanning Atomic Force Microscope Micro-Cantilever Probes. Atomic Force Microscopes (AFM's) are widely used for the examination of samples smaller than can be observed with an optical microscope. A tiny 'finger', only a few atoms wide at its sharpest point, is used to 'feel' the surface of a sample. This project aims to increase the resolution of AFM images by actively controlling the sensor probe dynamics.
Better quality AFM images would allow scientists ....Analysis, Optimization, and Control of Scanning Atomic Force Microscope Micro-Cantilever Probes. Atomic Force Microscopes (AFM's) are widely used for the examination of samples smaller than can be observed with an optical microscope. A tiny 'finger', only a few atoms wide at its sharpest point, is used to 'feel' the surface of a sample. This project aims to increase the resolution of AFM images by actively controlling the sensor probe dynamics.
Better quality AFM images would allow scientists to further investigate the atomic and molecular structure of such samples as: metals, polymers, cells, and proteins.
This research will contribute to the design of an Australian made Scanning Probe Microscope. Development of local expertise will provide a valuable resource for Australian scientific and industrial research.
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Microfibre photonics: function densification on a wavelength scale. The project will contribute to Australia's nanoscale device research and nanomanufacturing development. The project will create microfibre fabrication technologies for the creation of new optical systems of miniature proportions that will be used for cell illumination, for the creation of sensors for detection in small environments and as light tools for fundamental experiments in physics. Specialist fabrication methods will be ....Microfibre photonics: function densification on a wavelength scale. The project will contribute to Australia's nanoscale device research and nanomanufacturing development. The project will create microfibre fabrication technologies for the creation of new optical systems of miniature proportions that will be used for cell illumination, for the creation of sensors for detection in small environments and as light tools for fundamental experiments in physics. Specialist fabrication methods will be developed that will add to the nation's skill base. The outcomes of the project will enhance Australia's knowledge capacity, research capability and will contribute significantly to each of the National Research Priorities.Read moreRead less
Formation of Nanoporous titanium dioxide (TiO2) by Anodization of Titanium Thin Films. The development of nanoporous titanium dioxide (TiO2), with pore diameter less than 25 nm, represents a significant advance for both R&D and industrial applications. It is an invaluable material for the manufacture of a range of electronic and optical devices. These structures can be employed for the development of efficient thermoelectric coolers, highly sensitive biosensors as well as optical micro-devices w ....Formation of Nanoporous titanium dioxide (TiO2) by Anodization of Titanium Thin Films. The development of nanoporous titanium dioxide (TiO2), with pore diameter less than 25 nm, represents a significant advance for both R&D and industrial applications. It is an invaluable material for the manufacture of a range of electronic and optical devices. These structures can be employed for the development of efficient thermoelectric coolers, highly sensitive biosensors as well as optical micro-devices with high refractive index. In addition, nanoporous TiO2 has numerous applications in the fields of nanotechnology, bioengineering, diagnostics, materials science, and in the building industry. Australia will greatly benefit from the research and development of such a product with its promising market.Read moreRead less
Biomedical imaging with spins in nanoparticles: from single cell to whole-body scanning. The engineering of new biomedical technology is critical in underpinning our understanding of physiology and in the early detection of disease. This project will construct novel instrumentation for investigating normal and diseased physiology using bioagents based on diamond and ruby nanoparticles. The imaging and tracking techniques proposed are non-invasive, nontoxic, and provide high-resolution access to ....Biomedical imaging with spins in nanoparticles: from single cell to whole-body scanning. The engineering of new biomedical technology is critical in underpinning our understanding of physiology and in the early detection of disease. This project will construct novel instrumentation for investigating normal and diseased physiology using bioagents based on diamond and ruby nanoparticles. The imaging and tracking techniques proposed are non-invasive, nontoxic, and provide high-resolution access to specific physiological interactions of paramount importance in, for instance, understanding cancer pathways and developing strategies for targeted drug delivery.Read moreRead less