Rationale For Non-invasive Treatment Of Retinopathy Of Prematurity: Dark Rearing As A Means Of Mimicking Physiological Vascularisation
Funder
National Health and Medical Research Council
Funding Amount
$413,900.00
Summary
We aim to develop a new, non-invasive and cost-effective treatment for the disease Retinopathy of Prematurity, the leading cause of childhood blindness across the globe. We intend to test our hypothesis that raising neonates in conditions of total darkness and high oxygen will closely mimic conditions for inducing normal retinal vascular development, and thus prevent the initiating event of the disease. Ultimately, the project intends to lay the groundwork for a translation to the human conditio ....We aim to develop a new, non-invasive and cost-effective treatment for the disease Retinopathy of Prematurity, the leading cause of childhood blindness across the globe. We intend to test our hypothesis that raising neonates in conditions of total darkness and high oxygen will closely mimic conditions for inducing normal retinal vascular development, and thus prevent the initiating event of the disease. Ultimately, the project intends to lay the groundwork for a translation to the human condition.Read moreRead less
Context Is Everything – Understanding How Spatial, Temporal And Behavioural Context Affect Sensory Processing
Funder
National Health and Medical Research Council
Funding Amount
$512,382.00
Summary
A possum in a tree is cute to see on a bushwalk, but scary to hear when we are trying to sleep. This illustrates that how we perceive a “target” is affected by “modulators” that are close in space or time to the target, or by the task at hand. Deficits in contextual modulation are apparent in many neurological conditions. This project will investigate the neural circuitry that mediates spatial, temporal and task-related contextual modulation.