Environmental Influences In The Establishment Of The Epigenetic Landscape In Children
Funder
National Health and Medical Research Council
Funding Amount
$695,097.00
Summary
The DNA in each of our cells does not exist alone, it is packaged into complex structures called chromosomes, through association with many different proteins. The distribution of these proteins varies along the length of a chromosome depending on the type of cell and this phenomenon is called 'epigenetics', literally meaning 'above the DNA'. Epigenetic analysis is the study of how proteins and other molecules can change the activity of a gene without changing the DNA sequence. All of our cells ....The DNA in each of our cells does not exist alone, it is packaged into complex structures called chromosomes, through association with many different proteins. The distribution of these proteins varies along the length of a chromosome depending on the type of cell and this phenomenon is called 'epigenetics', literally meaning 'above the DNA'. Epigenetic analysis is the study of how proteins and other molecules can change the activity of a gene without changing the DNA sequence. All of our cells use epigenetic changes to help control how they grow and develop. Evidence suggests a direct link between diet and environmental influences on our epigenetic profile. Recent research has traced the origins of many of the health problems of adult life back to the earliest periods of development _ to the time spent in the womb and the first few years of life. If we are born with a low birth weight, we are more likely to get sick later in life. Overwhelming evidence exists that the environment in the womb is critical for a healthy birth weight (and health in later life) and it is thought that epigenetics may be the missing link between this environment, low birth weight, and therefore health in later life. In addition, mounting evidence supports a general link between epigenetic de-regulation and predisposition to disease. However, the timing and the overall contribution of environmental- genetic influences to the establishment of faulty epigenetic markings remain largely unknown. Twins are the best model to study this link as they share similar (but not identical environments) and some share identical genetic makeup. Using twins, Dr Jeffrey Craig and his team will investigate the factors in the prenatal environment that modify specific cells, leading to low birth weight and increase disease risk later in life. They predict that this occurs via specific changes in gene activity caused by epigenetic disruption.Read moreRead less
Mental Health Across Generations: Pre-and Post Conception Predicators Of Early Life Risks
Funder
National Health and Medical Research Council
Funding Amount
$666,231.00
Summary
In 2003, mental illnesses were among the ten leading causes of disease burden in Australia, accounting for 13% of the total burden of disease, according to the Australian Institute of Health and Welfare. Mental health problems and mental illness are among the greatest causes of disability, diminished quality of life, and reduced productivity. People affected by mental health problems often have high levels of morbidity and mortality, experiencing poorer general health and higher rates of death f ....In 2003, mental illnesses were among the ten leading causes of disease burden in Australia, accounting for 13% of the total burden of disease, according to the Australian Institute of Health and Welfare. Mental health problems and mental illness are among the greatest causes of disability, diminished quality of life, and reduced productivity. People affected by mental health problems often have high levels of morbidity and mortality, experiencing poorer general health and higher rates of death from a range of causes, including suicide. These conditions are significant in terms of prevalence and disease burden, and have far-reaching impacts for families, carers and others in the community. Mental health problems commonly cluster in families. However, few studies have previously been able to investigate the range of ways in which mental disorders may pass from one generation to another. Further, evidence suggests that influences that arise prior to conception may have major effects on early life risks such as development in utero, birth outcomes and early maternal infant bonding. Mental Health across Generations: Pre- and post-conception predictors of early life risks is a unique study that will examine antenatal maternal mental health and risk behaviours during pregnancy. The study will also examine the links between prior maternal mental health and later birth outcomes, and post natal maternal infant bonding. The risk processes to be tested will include genetic, epigenetic (changes in gene expression), physiological and psycho-social parameters.Read moreRead less
Abalone Aquaculture Subprogram: Early Life History Of Abalone (Haliotis Rubra, H. Laevigata): Settlement, Survival And Early Growth
Funder
Fisheries Research and Development Corporation
Funding Amount
$313,217.00
Summary
Abalone farming can be improved in Australia. The profit will be increased and the cost of production reduced:
· increased knowledge of the settlement process and development of a better settlement system resulting in low cost juvenile abalone is essential for both integrated abalone farms and for the supply of seed to growout farms;
· the development of a practical settlement protocol for abalone requires a greater understanding of microalgae requirements and their culture and ....Abalone farming can be improved in Australia. The profit will be increased and the cost of production reduced:
· increased knowledge of the settlement process and development of a better settlement system resulting in low cost juvenile abalone is essential for both integrated abalone farms and for the supply of seed to growout farms;
· the development of a practical settlement protocol for abalone requires a greater understanding of microalgae requirements and their culture and reduces the cost for abalone at the growout stage;
· the project will be integrated into the abalone aquaculture sub-program and has extensive industry involvement in developing the practical aspects;
· the aquaculture industry in Victoria is developing into a major growth area and investment opportunity and production is intended to triple by the end of 2001;
· the success of the Australian abalone aquaculture industry is dependent on developing methods that reduce costs in labour and growout time;
· the project will deliver information that can result in technically advanced culture methods that will maintain the competitive edge over low labour cost countries. Objectives: 1. To test performance of different settlement inducers at both the laboratory and commercial scale. 2. To improve the rate and consistency of abalone larval settlement. 3. To compare different microalgal diets for their nutritional value in terms of digestibility and growth. 4. To quantify the suitability of different microalgae for their ease of use, both for maintaining mass cultures and ability to recolonise settlement surfaces. 5. To increase growth and survival for the first two months of post-larval life at a commercial scale. Read moreRead less
A Study Of The Movement And Behaviour Of The Sand Crab (Portunus Pelagicus) Using Ultrasonic Tags
Funder
Fisheries Research and Development Corporation
Summary
Objectives: 1. Develop ultrasonic tags suitable for tracking & monitoring behaviour of sand crabs. 2. Develop simple methods of tracking tagged free-ranging crabs in Moreton Bay. 3. Obtain positional & Behavioural information over 24-hour periods to map movement of individual crabs
A Study Of The Distribution Of Post-larval And Juvenile Western King Prawn In Spencer Gulf, South Australia
Funder
Fisheries Research and Development Corporation
Summary
Objectives: 1. To identify settlement sites and seasonal variation in sites of post-larval P. latisulcatus; 2. identify common parameters of these preferred areas that may condition settling (salinity, temp, sediment type)
Establishment Of A Professional Association Of Australian Fisheries Managers
Funder
Fisheries Research and Development Corporation
Funding Amount
$49,961.47
Summary
The Commonwealth and States have shared responsibility for the management of Australia’s fisheries resources under a Federal system of Government. This can create a number of challenges, foremost of which is incompatible management arrangements applying to the same fish stock across jurisdictions. Other issues include the lack of awareness, engagement and communication between fisheries managers working on common fisheries problems across jurisdictions and reductions in government funding for fi ....The Commonwealth and States have shared responsibility for the management of Australia’s fisheries resources under a Federal system of Government. This can create a number of challenges, foremost of which is incompatible management arrangements applying to the same fish stock across jurisdictions. Other issues include the lack of awareness, engagement and communication between fisheries managers working on common fisheries problems across jurisdictions and reductions in government funding for fisheries management and research.
There is a recognised need to increase cross-institutional engagement so line managers (as in those staff engaged in the development and implementation of fisheries management and policy) are made more cognisant of the work being undertaken across jurisdictions, thereby increasing their knowledge, skills and understanding of fisheries issues and solutions, with the aim of achieving management efficiencies. Due to budgetary cuts and increased workloads, Australian fisheries managers have very little time or opportunity to communicate and network with their associates within other institutions. The establishment of a professional association of Australian fisheries managers would facilitate collaboration and engagement by providing a forum for discussion/debate as well as acting as a repository for information and coordinator for future workshops and meetings on key focus areas. Qualified and experienced fisheries managers, despite their pivotal role in sustainable fisheries, are largely unrecognised as inter-disciplinary professionals in their own right. This is in contrast to fisheries biologists and economists. The formation of the association could lead to increased recognition of fisheries management as a profession. There would also be a value to industry through synergizing management approaches across jurisdictions, increasing efficiency and thereby reducing possible costs of management.
Objectives: 1. Establishment of Professional Association of Australian Fisheries Managers 2. Improved accessibility and transparency of jurisdictional fisheries management information (technical papers, policy and legislation) through hosting of a central website 3. Increased recognition of the profession of fisheries management within Australia and the current work undertaken by managers to ensure fisheries remain sustainable 4. Exposure of fisheries managers to innovations and developments in fisheries ecological, economic, social and political fields in Australia and overseas 5. Improved consistency and transparency in management approaches between jurisdictions through greater information-sharing and liaison 6. Establishment of linkages between fisheries managers for future interactions and collaborative engagement 7. Improved public confidence in Australian fisheries management through greater stakeholder outreach and communication 8. Ensuring the Association has appropriate support (financial and logistical) to operate beyond the completion of the two year project Read moreRead less
A Multi-setting Intervention To Reduce Sedentary Behaviour, Promote Physical Activity And Improve Childrens Health
Funder
National Health and Medical Research Council
Funding Amount
$860,343.00
Summary
Sedentary behaviours and physical inactivity play a major role in the rising prevalence of obesity among children in Australia. This intervention study will take place in the school and family settings which play a critical role in shaping children's health behaviours. The objective is to determine whether a 2-year behavioural intervention reduces sedentary behaviour and promotes physical activity and results in improved health among 8-9 year old children.
Honesty and efficiency in the provision of expert services: doctors and other experts as participants in economic experiments. Experts serve us when we see the doctor, the financial planner or the car mechanic. In all these case the expert can take advantage of his superior knowledge and sell us something we do not need. This research will inform policy makers about the underlying motives of real world experts and allow them to design better institutions.
A sponsor’s page including logos will be included at the start and end of each session (4 times) and will include acknowledgement at the start and conclusion of the summit. Major sponsors will also be acknowledged in social media posts about the summit. A media release prior to the summit will include acknowledgment of major sponsors.