Improving The Health And Development Of High Risk Preterm Newborns
Funder
National Health and Medical Research Council
Funding Amount
$338,381.00
Summary
Preterm children have more health and developmental problems than those born full term. Although we know the problems faced by those tiniest and most immature, more questions remain. What problems do they face as adults? What new treatments are available to improve their outcomes? Are the more “mature” preterms at risk as well? My research program aims to address these questions through the efforts of the Victorian Infant Collaborative Study team, a large research team that I lead.
Impact Of Parental Alcohol, Tobacco And Other Substance Use On Infant Development And Family Functioning
Funder
National Health and Medical Research Council
Funding Amount
$1,996,525.00
Summary
The current study will be the first large-scale Australian birth cohort study to comprehensively examine the effects of substance use in pregnant women and their partners during the prenatal period on infant developement and family functioning. Dramatically improved knowledge of these effects will provide evidence-based direction to the development of public health policy and community interventions that aim to improve the health and wellbeing of Australian children and families.
Limiting Weight Gain In Overweight And Obese Women During Pregnancy To Improve Health Outcomes - A Randomised Trial.
Funder
National Health and Medical Research Council
Funding Amount
$1,541,444.00
Summary
Being overweight or obese is a major health issue for women during pregnancy and childbirth in Australia. There are well documented risks associated with obesity during pregnancy for both the mother and her baby. This randomised trial will assess whether the implementation of a package of dietary and lifestyle advice to overweight and obese pregnancy women to limit weight gain during pregnancy is effective in improving health outcomes for women and their babies.
Fetal Middle Cerebral Artery Doppler To Time Second And Subsequent Fetal Transfusions For Red Cell Alloimmunisation.
Funder
National Health and Medical Research Council
Funding Amount
$449,585.00
Summary
Blood group incompatability between a mother and her unborn baby can result in the production of antibodies that can damage the baby's red blood cells, causing anaemia. Treatment involves a procedure to transfuse blood to the baby while in the mother's uterus, which often needs to be repeated several times during a pregnancy. This randomised trial will assess if an ultrasound examination can be used to time second or subsequent fetal transfusions, and the impact this has on infant health.
Vaginal Progesterone For The Prevention Of Neonatal Respiratory Distress Syndrome - A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$935,107.00
Summary
Respiratory distress syndrome is a significant problem for babies born preterm. For these babies, a significant number will require support for their breathing. These babies are also at increased risk of dying, and in survivors, there is a risk of long-term disability. It is uncertain if giving vaginal progesterone therapy during pregnancy to women who have had a previous preterm birth can reduce these risks.
Vaginal Progesterone For The Prevention Of Neonatal Respiratory Distress Syndrome - A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,243,111.00
Summary
Respiratory Distress Syndrome is a significant problem for babies born very preterm (at less than 34 weeks of pregnancy). For these babies, over 90% will require support for their breathing. These babies are also at increased risk of dying, and in survivors, there is a risk of long-term disability. It is uncertain if giving vaginal progesterone therapy during pregnancy to women who have had a previous preterm birth can reduce these risks. This randomised controlled trial will assess the use of v ....Respiratory Distress Syndrome is a significant problem for babies born very preterm (at less than 34 weeks of pregnancy). For these babies, over 90% will require support for their breathing. These babies are also at increased risk of dying, and in survivors, there is a risk of long-term disability. It is uncertain if giving vaginal progesterone therapy during pregnancy to women who have had a previous preterm birth can reduce these risks. This randomised controlled trial will assess the use of vaginal progesterone therapy for women at risk of preterm birth as a means of reducing the risk of neonatal Respiratory Distress Syndrome and improving the outcomes of their babies.Read moreRead less
Does Bovine Lactoferrin Prevent Death Or Disability In Very Low Birthweight Infants? Childhood Follow Up In The NHMRC LIFT Study
Funder
National Health and Medical Research Council
Funding Amount
$1,474,012.00
Summary
Our international consortium of investigators proposes to undertake follow up in survivors among 1,500 very low birth weight preterm infants enrolled in the NHMRC Lactoferrin Infant Feeding Trial, which is designed to evaluate whether low-cost oral lactoferrin supplementation reduces death and disability in early childhood.
Health Status And Development Among Aboriginal Infants In An Urban Community.
Funder
National Health and Medical Research Council
Funding Amount
$436,650.00
Summary
This research is a descriptive study of the health outcomes of Aboriginal infants, born at Campbelltown Hospital. The research will build on Centre for Health Equity's (CHETRE) work, since 1997, with the Aboriginal community, Aboriginal Medical Service (AMS) and Area Health Services (AHS) in the region to develop and advocate for services to address the needs of Aboriginal and other disadvantaged communities. CHETRE has supported the Aboriginal workers to develop additional services for Aborigin ....This research is a descriptive study of the health outcomes of Aboriginal infants, born at Campbelltown Hospital. The research will build on Centre for Health Equity's (CHETRE) work, since 1997, with the Aboriginal community, Aboriginal Medical Service (AMS) and Area Health Services (AHS) in the region to develop and advocate for services to address the needs of Aboriginal and other disadvantaged communities. CHETRE has supported the Aboriginal workers to develop additional services for Aboriginal women, such as the Aboriginal Home Visiting Team (AHV) and assisted with evaluation of these services. The AHV management comprises representatives from AMS, AHS, the Aboriginal community and CHETRE, and will provide advice and oversight for this project. The AHV developed from community concern about health status of Aboriginal infants and provides ante and postnatal care to infants and mothers. As a part of this service Aboriginal infants are systematically identified by the AHS. Further development of services is limited by lack of information on health status, use of health services, or achievement of developmental milestones by Aboriginal infants in an urban community and the assumption that outcomes are a factor of disadvantage. The researchers intend to describe in meticulous detail obstetric outcomes for 150 Aboriginal infants and their mothers born in 2004-5 and the health and development outcomes of the infants at 12 months. Baseline information on birth weight, Apgar score and obstetric history will be collected from maternal report at 2-3 week post-delivery and from routine data collections. Infants and their mothers will be followed up prospectively with further data collection points at 6 months and 12 months. Information on health status, health service use, and achievement of developmental milestones will be obtained by measurement and maternal report. An assessment by a paediatrician will be undertaken at 12 months.Read moreRead less