Diseases caused by the pneumococcus represent the largest cause of vaccine preventable death in the world today, mainly pneumonia and meningitis. In 2011, 16 developing countries will introduce pneumococcal conjugate vaccines, none in east Asia. Lack of research has been a major barrier to their use in the region. We have established an international centre of excellence in the field and we seek support to extend the capacity of this group and to transfer the technology to Vietnam.
Troublesome ticks: a new molecular toolkit to investigate zoonotic tick-borne pathogens in Australia. This project will use the latest molecular diagnostic techniques to address unanswered questions about potential tick-transmitted diseases of humans and companion animals in Australia. The study will identify 'hot-spots' for tick-borne pathogens, identify areas of potential risk for humans, and investigate vector-host-pathogen interactions nationwide.
Ecology and transmission of tick-borne disease in Australia. Ecology and transmission of tick-borne disease in Australia. This project aims to determine the bacterial, protozoal and viral biodiversity in wildlife ticks and their native mammal hosts, and provide new information about the biology and transmission dynamics of these microorganisms and their potential to cause disease in wildlife, domesticated animals and humans. Anticipated outcomes are improved diagnostic tests and management proto ....Ecology and transmission of tick-borne disease in Australia. Ecology and transmission of tick-borne disease in Australia. This project aims to determine the bacterial, protozoal and viral biodiversity in wildlife ticks and their native mammal hosts, and provide new information about the biology and transmission dynamics of these microorganisms and their potential to cause disease in wildlife, domesticated animals and humans. Anticipated outcomes are improved diagnostic tests and management protocols for tick-borne disease in Australia.Read moreRead less
Controlling cane toads by turning their own weapons against them. This project aims to prevent cane toads, which are causing ecological havoc across tropical Australia, from breeding successfully. Attempts to control toad populations have had little impact, but recent research has revealed a new possibility — exploiting the toads' own weapons for intraspecific conflict. Larval cane toads compete intensely with other larval cane toads and as a result, have evolved a way to kill off their competit ....Controlling cane toads by turning their own weapons against them. This project aims to prevent cane toads, which are causing ecological havoc across tropical Australia, from breeding successfully. Attempts to control toad populations have had little impact, but recent research has revealed a new possibility — exploiting the toads' own weapons for intraspecific conflict. Larval cane toads compete intensely with other larval cane toads and as a result, have evolved a way to kill off their competitors. Toad tadpoles produce chemicals that have devastating effects on younger members of their own species, but not on native species. By deploying those chemicals, this project could develop a novel and powerful form of invader control.Read moreRead less
WAVELET-BASED MODELLING AND MODEL PREDICTIVE CONTROL OF COMPLEX MULTIDIMENSIONAL CRYSTALLISATION PROCESSES. The results of this project will directly contribute to a better understanding of crystallisation which is an important unit operation to achieve high purity separations. Many Australian industries for example, mineral processing, sugar processing, pharmaceuticals, etc will benefit from the results in order to enhance optimal operation and control to ensure globally competitive production ....WAVELET-BASED MODELLING AND MODEL PREDICTIVE CONTROL OF COMPLEX MULTIDIMENSIONAL CRYSTALLISATION PROCESSES. The results of this project will directly contribute to a better understanding of crystallisation which is an important unit operation to achieve high purity separations. Many Australian industries for example, mineral processing, sugar processing, pharmaceuticals, etc will benefit from the results in order to enhance optimal operation and control to ensure globally competitive production which is on time, minimize wastes and raw materials and inventories. The leading edge results will increase the contributions of these industries to the Australian economy and our global competitiveness necessary to maintain our culture and the beauty of our environment. Read moreRead less
Impact Of DTP Schedules On The Immunogenicity Of 2 Doses Of 13v-PCV Followed By An Early Booster
Funder
National Health and Medical Research Council
Funding Amount
$2,651,687.00
Summary
This project aims to come up with a vaccination schedule to make pneumococcal vaccines more effective and affordable for Fiji and other developing countries. We will evaluate schedules involving a 2 dose primary series in early infancy with a booster at 9 months of age. We will compare the immune responses to 3 different primary series and 2 booster options. The results of this project will be used to provide advice, at global and country levels, regarding introduction of pneumococcal vaccines.
Convex optimisation for control, signal processing and communication systems. Renewable control of complex systems, signal processing, telecommunication and in general any industries interested in these applications stand to benefit from our research. In particular, the automotive and defence industries stand to benefit from the nonlinear control design aspect of the proposed project outcomes. The
telecommunications industries, on the other hand, benefit from the signal processing and communicat ....Convex optimisation for control, signal processing and communication systems. Renewable control of complex systems, signal processing, telecommunication and in general any industries interested in these applications stand to benefit from our research. In particular, the automotive and defence industries stand to benefit from the nonlinear control design aspect of the proposed project outcomes. The
telecommunications industries, on the other hand, benefit from the signal processing and communications aspects. We also build a core expertise in optimisation and its applications in Australia by training PhD students and Postdoctoral researchers. The research collaborations will cement and maintain the international linkages which will improve applied research in AustraliaRead moreRead less
The return of the native: reintroductions, reinvasions, and a new paradigm in restoration ecology. We develop a new solution to improve pest control used to protect rare and endangered wildlife by using reintroductions of common native species as a block to reinvasion following pest control. Our approach will significantly reduce the ongoing costs of pest control in Australia and our solution can be used by both large conservation organisations as well as small community groups aiming to control ....The return of the native: reintroductions, reinvasions, and a new paradigm in restoration ecology. We develop a new solution to improve pest control used to protect rare and endangered wildlife by using reintroductions of common native species as a block to reinvasion following pest control. Our approach will significantly reduce the ongoing costs of pest control in Australia and our solution can be used by both large conservation organisations as well as small community groups aiming to control pests and protect key wildlife. Our technique can also be exported to solve alien species problems elsewhere in the world. This work strengthens Australia’s world renowned expertise for research into alien species and ability to develop novel solutions to alien impacts.Read moreRead less
Ecology, impact and control of cane toads on the southern invasion front. The invasion of cane toads has killed many native animals in tropical Australia, but the toads’ southern (NSW) invasion front remains unstudied. This project will build on recent research to understand how toads affect southern biodiversity, and will develop new ways to reduce that impact.
Improving Sexual Health In Men With Prostate Cancer: Randomised Controlled Trial Of Exercise And Psychosexual Therapies
Funder
National Health and Medical Research Council
Funding Amount
$583,416.00
Summary
Sexual dysfunction is one of the most common and distressing side effects of prostate cancer. Despite being a critical survivorship care issue, there is a clear gap in knowledge surrounding the optimal treatment of sexual dysfunction in men with prostate cancer. This project examines whether exercise aids in the management of sexual dysfunction and explores if an integrated treatment model incorporating pharmacological, exercise and psychosexual therapies maximises improvement in sexual health.