Young Adult Myopia: Genetic And Environmental Associations
Funder
National Health and Medical Research Council
Funding Amount
$809,271.00
Summary
Myopia affects 80% of school leavers in the cities of East Asia, 45% of Asian Australian school leavers and is probably on the rise in European Australian adolescents. Increased levels of education and lack of time outdoors are known to increase the risk of myopia. We will examine 2,000 young adults to find the genes that interact with these risk factors. In addition to confirming when these risk factors are most important, identifying molecular pathways opens the avenue of new treatments.
Health And Fertility Of Young Men Conceived Using Intra-cytoplasmic Sperm Injection
Funder
National Health and Medical Research Council
Funding Amount
$362,570.00
Summary
The injection of a single sperm into the egg (ICSI) has been the main IVF treatment for men with poor sperm quality since 1993 but is now often used for other types of infertility. Concern has been raised about the health of the children. We will approach >800 parents and their adult sons conceived using ICSI and will assess his general health and development, and fertility. This work will improve patient counselling and practice guidelines, and direct research into the safety of ICSI.
Studies On The Expression Of Muscarinic Receptors: Implications For The Pathology Of Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$498,791.00
Summary
Schizophrenia is a severe psychiatric disorder that affects approximately 1% of the population. This project will help define changes in the molecules in the brain of subjects with schizophrenia which are likely to be involved in two symptoms of the disorder, the psychoses and cognitive deficits. Understanding the cause of the cognitive deficits of schizophrenia is a high priority because they are the most disabilitating symptom of the disorder and do not respond to current drug treatments.
Associations Between Urban Nature And Cardiovascular Disease Risk
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Cardiovascular disease (CVD) is the leading cause of death in Australia. Urban nature (e.g. greenness, water, species diversity) is likely to protect against CVD, yet researchers lack knowledge about how this occurs. This project will develop new methods to measure urban nature and examine the relationships with different CVD risk factors (e.g. physical activity, air quality). The results of this project will inform urban planning policy, and help to create healthy cities that reduce CVD.
Australian Health Inequities Program: A Program Addressing Social And Economic Determinants Of Health
Funder
National Health and Medical Research Council
Funding Amount
$2,444,000.00
Summary
The Australian Health Inequities Program, AHIP, is an exciting new program which brings together researchers from a range of disciplines including sociology, public health, labour market economics, housing and geography to research health inequities and analyse policy and program responses to reduce these inequities. This will be done by addressing ways in which our housing, employment, the availability and quality of our social connections, the locations we live in, and perceptions of our envir ....The Australian Health Inequities Program, AHIP, is an exciting new program which brings together researchers from a range of disciplines including sociology, public health, labour market economics, housing and geography to research health inequities and analyse policy and program responses to reduce these inequities. This will be done by addressing ways in which our housing, employment, the availability and quality of our social connections, the locations we live in, and perceptions of our environments, affect health. The researchers, based at Flinders University in Adelaide and La Trobe University in Melbourne, will identify how the physical and social characteristics of local environments impact on health. The research conducted in this program will provide guidance to government, service providers and community groups about how to improve the quality of people's local environments and reduce the health differences between different groups of Australians. Policy makers will be engaged fully with the AHIP.Read moreRead less
Assessing Infrastructure And Contextual Factors In Relation To Cardiometabolic Outcomes In Remote Indigenous Communities: Evidence For Policy Change
Funder
National Health and Medical Research Council
Funding Amount
$1,113,005.00
Summary
Cardiometabolic diseases account for the major burden of morbidity and mortality for Indigenous populations. This study with 75 remote Indigenous communities will be the first to evaluate features of their social, built and physical environments in relation to cardiometabolic risks and diseases. Policy-relevant results will identify features of environments to be targeted to reduce chronic diseases for Indigenous peoples in remote communities.
Epigenetic Programming Of Immune Development In Utero: Role Of The Maternal Environment In The Allergy Epidemic
Funder
National Health and Medical Research Council
Funding Amount
$764,463.00
Summary
This study will provide new insights into the development of allergic disease. Specifically, we will explore the hypothesis that allergic disease and other disorders or immune dysregulation occur as a result of gene-environmental interactions in early life, and that these events begin in pregnancy when the developing fetus is still developing and most susceptible to these effects.