Impact of roughness on adverse pressure gradient turbulent boundary layers. This project aims to develop a novel technique for measuring time-resolved fluid velocity vector fields in high-speed flows to investigate rough wall turbulence in adverse pressure gradient environments in unprecedented detail. By using this innovative instrument to study these widespread but poorly understood turbulent flows in power generation and transport, the project seeks to generate new knowledge. Expected outcome ....Impact of roughness on adverse pressure gradient turbulent boundary layers. This project aims to develop a novel technique for measuring time-resolved fluid velocity vector fields in high-speed flows to investigate rough wall turbulence in adverse pressure gradient environments in unprecedented detail. By using this innovative instrument to study these widespread but poorly understood turbulent flows in power generation and transport, the project seeks to generate new knowledge. Expected outcomes include the development of a new instrument and fundamental knowledge leading to improved designs with higher efficiencies in power generation and transport, resulting in significant benefits such as increased energy security, reduced greenhouse gas emissions, and improved quality of life for individuals and society.Read moreRead less
Microfluidics to explore the uptake of nanoparticles by endothelial cells. This project aims to develop microfluidic technologies for generating lipid nanoparticles with customised properties and investigating their delivery to endothelial cells under various flow dynamics. The project expects to advance our fundamental knowledge of biophysical and biological mechanisms underlying the uptake of lipid nanoparticles by endothelial cells. Expected outcomes of this project include enhanced delivery ....Microfluidics to explore the uptake of nanoparticles by endothelial cells. This project aims to develop microfluidic technologies for generating lipid nanoparticles with customised properties and investigating their delivery to endothelial cells under various flow dynamics. The project expects to advance our fundamental knowledge of biophysical and biological mechanisms underlying the uptake of lipid nanoparticles by endothelial cells. Expected outcomes of this project include enhanced delivery of nanoparticles to vessel walls. This should provide significant benefits, such as establishing a framework for designing future nano delivery systems, which would benefit Australian biotechnology industries.
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On the Hunt: Boosting Productivity of Cell Factories by Advanced Searches . This project aims to advance our fundamental understanding of molecular mechanisms underlying protein secretion in yeast, an industrial workhorse and a model organism. It will develop a unique multifaceted research platform to identify and analyse superior yeast strains with the desired traits at the single-cell level. Expected outcomes include a new analytical tool for high-throughput strain analysis and advanced knowle ....On the Hunt: Boosting Productivity of Cell Factories by Advanced Searches . This project aims to advance our fundamental understanding of molecular mechanisms underlying protein secretion in yeast, an industrial workhorse and a model organism. It will develop a unique multifaceted research platform to identify and analyse superior yeast strains with the desired traits at the single-cell level. Expected outcomes include a new analytical tool for high-throughput strain analysis and advanced knowledge of yeast molecular biology that can be applied to improve cell factories for the next generation of fuels, food and pharmaceuticals. This will provide significant economic and social benefits by boosting biotech industry growth, facilitating the transition to a sustainable society and improving Australia’s biosecurity.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240101027
Funder
Australian Research Council
Funding Amount
$414,000.00
Summary
Deciphering the mechanisms of object manipulation with viscoelastic fluids. This project aims to innovate how tiny objects in mixed samples are sorted using the forces generated by fluids that are both viscous and elastic. The developed technology is expected to break the limitations of conventional methods by automating sample processing and by enabling the sorting capability based on not only size, but also shape and fluid properties. This will meet the growing demand for rapid processing of c ....Deciphering the mechanisms of object manipulation with viscoelastic fluids. This project aims to innovate how tiny objects in mixed samples are sorted using the forces generated by fluids that are both viscous and elastic. The developed technology is expected to break the limitations of conventional methods by automating sample processing and by enabling the sorting capability based on not only size, but also shape and fluid properties. This will meet the growing demand for rapid processing of complex real-world environmental samples. The expected outcomes include new knowledge and techniques for sorting algae and insects from water samples for the assessment of water quality and biodiversity. It is expected to benefit Australians by providing faster, cheaper, and more efficient environmental monitoring methods.Read moreRead less
Harnessing the Power of Wind: Revolutionising Wind Farm Optimisation. This project aims to develop a rigorous, efficient and accurate framework for optimisation of control policies for complete wind farms. It expects to generate new knowledge in data-driven physics informed transient aerodynamic and structural modelling of entire wind farms, generation of low order yet sufficiently accurate models using machine learning, and game-theoretic and model predictive control techniques for operation of ....Harnessing the Power of Wind: Revolutionising Wind Farm Optimisation. This project aims to develop a rigorous, efficient and accurate framework for optimisation of control policies for complete wind farms. It expects to generate new knowledge in data-driven physics informed transient aerodynamic and structural modelling of entire wind farms, generation of low order yet sufficiently accurate models using machine learning, and game-theoretic and model predictive control techniques for operation of an entire wind farm. Expected outcomes are engineering tools to tackle wind farm inefficiencies totalling $700m/year in Australia alone, contributing to energy stability, security and lowered emissions aligned to the National Science and Research Priority ‘Energy’.Read moreRead less
Scaling laws for aerodynamics of moving wings in the Martian atmosphere. This project aims to increase understanding of the aerodynamics of bio-inspired flight in the low-density atmosphere of Mars. The significance of flight in planetary exploration is shown by the ongoing success of the Ingenuity helicopter on Mars, and the Dragonfly rotorcraft planned for use on Titan. Expected outcomes of this project will be innovative numerical modelling techniques validated using local specially designed ....Scaling laws for aerodynamics of moving wings in the Martian atmosphere. This project aims to increase understanding of the aerodynamics of bio-inspired flight in the low-density atmosphere of Mars. The significance of flight in planetary exploration is shown by the ongoing success of the Ingenuity helicopter on Mars, and the Dragonfly rotorcraft planned for use on Titan. Expected outcomes of this project will be innovative numerical modelling techniques validated using local specially designed low-pressure experimental facilities. Benefits will be more accurate design guidance for efficient and robust flapping and rotary wing robotic vehicles for Mars and other space exploration that take advantage of the unique atmospheric conditions, and in placing Australia at the forefront of such design technology.Read moreRead less
How do vortices live in spatio-temporally complex flows? The project aims to understand the fundamental mechanism of vortices occurring in flows involving spatio-temporal complexity, by using the combination of dynamical systems theory and asymptotic analysis. This innovative combined mathematical analysis will be coupled with sophisticated computations to be enabled by the international interdisciplinary collaboration between the Mathematics and Engineering at Australia and Japan. The expected ....How do vortices live in spatio-temporally complex flows? The project aims to understand the fundamental mechanism of vortices occurring in flows involving spatio-temporal complexity, by using the combination of dynamical systems theory and asymptotic analysis. This innovative combined mathematical analysis will be coupled with sophisticated computations to be enabled by the international interdisciplinary collaboration between the Mathematics and Engineering at Australia and Japan. The expected outcomes are breakthroughs in the fundamental understanding of turbulence. This should lead to significant insight into better turbulent modellings used in, for example, wide range of engineering, physiological and geophysical flows.Read moreRead less
Novel framework for optimising battery-cooling microchannel heat exchangers. Thermal overheating can affect the capacity, safety and life expectancy of batteries for renewable energy storage and electric vehicles. Microscale heat exchangers are a potential high-efficiency, low-bulk solution. This project aims to develop a novel computational methodology to optimise the design of those heat exchangers in which viscoelastic fluids are used to control flow instabilities and enhance heat transfer at ....Novel framework for optimising battery-cooling microchannel heat exchangers. Thermal overheating can affect the capacity, safety and life expectancy of batteries for renewable energy storage and electric vehicles. Microscale heat exchangers are a potential high-efficiency, low-bulk solution. This project aims to develop a novel computational methodology to optimise the design of those heat exchangers in which viscoelastic fluids are used to control flow instabilities and enhance heat transfer at the microscale. A new microscopic fluid physics model will provide data for an innovative neural network framework to optimise the working fluid conditions and microscale design, which could contribute to increased adoption of renewable energy technologies that are supported by microscale heat exchangers.Read moreRead less
Thermal Optimisation of Gigascale Solar Photovoltaics. Large-scale solar photovoltaics are critical to decarbonising the global economy. Sun Cable is developing the world’s largest solar farm in the Northern Territory, and is considering deploying the 5B MAV solar array. At this scale, temperature-induced panel efficiency losses represent a major challenge that must be overcome through thermal performance optimisation. We will build sophisticated multiscale models to simulate and understand the ....Thermal Optimisation of Gigascale Solar Photovoltaics. Large-scale solar photovoltaics are critical to decarbonising the global economy. Sun Cable is developing the world’s largest solar farm in the Northern Territory, and is considering deploying the 5B MAV solar array. At this scale, temperature-induced panel efficiency losses represent a major challenge that must be overcome through thermal performance optimisation. We will build sophisticated multiscale models to simulate and understand the multiple interacting phenomena that cause panel heating, for the first time. This project will create the tools and know-how to optimise array design and solar farm development, delivering major efficiency gains and enhancing the viability of future gigascale solar projects.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100400
Funder
Australian Research Council
Funding Amount
$425,963.00
Summary
Fallopian tube on-a-chip for understanding mammalian reproduction. This project aims to reveal the fundamental physics and biology of mammalian reproduction by engineering the first comprehensive 3D culture model of the fallopian tube. The project expects to generate significant new knowledge about the exact role of the fallopian tube anatomy and physiology on the formation and function of epithelial tissue, using innovative approaches to simultaneously measure the full dynamics of epithelial ce ....Fallopian tube on-a-chip for understanding mammalian reproduction. This project aims to reveal the fundamental physics and biology of mammalian reproduction by engineering the first comprehensive 3D culture model of the fallopian tube. The project expects to generate significant new knowledge about the exact role of the fallopian tube anatomy and physiology on the formation and function of epithelial tissue, using innovative approaches to simultaneously measure the full dynamics of epithelial cell activity and sperm motion. The expected outcome of the project is to reveal the cooperative role of sperm, egg and epithelial tissue on fertilisation. This should provide significant benefits, such as important biophysical insights into mammalian reproduction and new research tools to replace animal models.Read moreRead less