The implications of resistance training for the control of movement. Resistance training (or weight lifting) is an essential element of comprehensive rehabilitation programs in a wide range of clinical settings. However, because we know little about how the organization of the nervous system is affected by training with high loads, the consequences of resistance training for our ability to control functional movements are unclear. The ultimate goal of this research is to generate basic knowledge ....The implications of resistance training for the control of movement. Resistance training (or weight lifting) is an essential element of comprehensive rehabilitation programs in a wide range of clinical settings. However, because we know little about how the organization of the nervous system is affected by training with high loads, the consequences of resistance training for our ability to control functional movements are unclear. The ultimate goal of this research is to generate basic knowledge about the impact of resistance training on nervous system function. The research will lead to the design of injury prevention and rehabilitation programs that are maximally effective, and provide a genuine benefit to the community.Read moreRead less
The Role Of The Orbitofrontal Cortex In Disorders Of Response Inhibition
Funder
National Health and Medical Research Council
Funding Amount
$515,488.00
Summary
We will investigate the role of the orbitofrontal cortex (OFC) in decision-making, particularly the effect of hyperactivity in the medial vs. ventrolateral orbitofrontal cortex on decision-making. Hyperactivity in these structures has been linked to obsessive compulsive disorder and, in line with the distinct functions of the different regions of OFC, we develop and test a novel hypothesis as to the psychological and neural bases of the obsessions and compulsions distinctive to that disorder.
Evaluating the impact of obesity on knee load over time in those who have undergone optimal surgical re-alignment after total knee replacement . This project investigates the impact of obesity on alignment and knee load over time in those who have undergone total knee replacement. This information is critical for understanding whether obesity results in increasing knee load after surgery which can lead to more rapid wearing of the knee surfaces and an earlier need for revision surgery.
Australia’s role in Global Financial and Production Networks. The project intends to address a major deficit of knowledge about the ways financial centres develop and compete among a network of international centres. Australia’s long-term economic future is closely tied to providing financial services throughout Asia. Yet very little attention has been given to analysing the structures and networks that enable internationalisation, in particular the performance of Sydney and Melbourne as competi ....Australia’s role in Global Financial and Production Networks. The project intends to address a major deficit of knowledge about the ways financial centres develop and compete among a network of international centres. Australia’s long-term economic future is closely tied to providing financial services throughout Asia. Yet very little attention has been given to analysing the structures and networks that enable internationalisation, in particular the performance of Sydney and Melbourne as competitive financial centres within a network of financial centres in East and South-East Asia. Using specialist industry databases and intensive case study methods, this project plans to examine the processes underpinning the growth of this network, map scenarios for the next two decades, and advise on policy implications arising from the 2013–14 Financial System Inquiry.Read moreRead less
Tracing modes of infrastructure financing and their effects on cities. Urban infrastructure is seen to be in crisis. In response, cash-strapped governments defer increasingly to private financiers and operators. This project assesses the changes required of infrastructure to meet the expectations of private finance. It will also assess how infrastructure items are being transformed as modes of finance move from one city to another.
Encephalitis lethargica in the 1920s (and afterwards): the forgotten epidemic. An unusually aggressive encephalitis epidemic swept the globe between 1915 and 1925. Two-thirds of victims survived the initial phase, but most developed severe neurological syndromes, especially parkinsonism, which crippled them for the remainder of their lives. The cause of this catastrophe, largely forgotten despite huge costs in both human and economic terms, has never been established, and its return cannot be ex ....Encephalitis lethargica in the 1920s (and afterwards): the forgotten epidemic. An unusually aggressive encephalitis epidemic swept the globe between 1915 and 1925. Two-thirds of victims survived the initial phase, but most developed severe neurological syndromes, especially parkinsonism, which crippled them for the remainder of their lives. The cause of this catastrophe, largely forgotten despite huge costs in both human and economic terms, has never been established, and its return cannot be excluded. Medicohistorical techniques, current neurological awareness and social analysis will be employed to produce the first history of the epidemic, whereby insights into both its nature and into parkinsonism, one of the most frequent neurological disorders in our ageing population, are expected.Read moreRead less
Situated Design Computing: A New Paradigm to Support Design Using Situated Reasoning. A country like Australia with its twin disadvantages of distance from its large markets and small population as its own market has to found its goals in its wealth production on its ability to compete at the high value-adding loci of the economy. Design is a precursor to superior products and is one of the nation's high value-adding wealth generating activities. This project aims to lay the foundations for a ....Situated Design Computing: A New Paradigm to Support Design Using Situated Reasoning. A country like Australia with its twin disadvantages of distance from its large markets and small population as its own market has to found its goals in its wealth production on its ability to compete at the high value-adding loci of the economy. Design is a precursor to superior products and is one of the nation's high value-adding wealth generating activities. This project aims to lay the foundations for a new class of design support tools that have the capacity to be used at a variety of stages in the design process including those stages where major decisions are being taken. This will have the potential to improve the efficacy and the efficiency of Australian design and hence make it more globally competitive.Read moreRead less
Efficient and Effective Interactive Visualization of Large Graphical Information Spaces. The expected outcome will change ways of interacting with and thinking about information processing for all information systems. As Australian companies became larger and more global, the ability to view and analyse the growing amount of company information becomes crucial to aspects as varied as trouble shooting or new ventures and eventually to the very viability of the organization itself. The expected ou ....Efficient and Effective Interactive Visualization of Large Graphical Information Spaces. The expected outcome will change ways of interacting with and thinking about information processing for all information systems. As Australian companies became larger and more global, the ability to view and analyse the growing amount of company information becomes crucial to aspects as varied as trouble shooting or new ventures and eventually to the very viability of the organization itself. The expected outcome will enhance this ability by providing an optimised global view and an effective navigation scheme of large graphical information spaces. This will attract leading international IT companies to use it for developing cutting-age tools, and will enhance significantly the capacity and international standing of Australian IT industry.Read moreRead less
An Integrative and Interactive Approach for Co-estimation of Multiple Sequence Alignment and Phylogeny Reconstruction. In this project innovative IT methods will be developed to assist biologists to solve complex and important biological problems. Many important applications in computational biology need very accurate and reliable tools for multiple sequence alignment and phylogeny reconstruction. Unfortunately, current existing tools are unreliable and are prone to serious errors when applied t ....An Integrative and Interactive Approach for Co-estimation of Multiple Sequence Alignment and Phylogeny Reconstruction. In this project innovative IT methods will be developed to assist biologists to solve complex and important biological problems. Many important applications in computational biology need very accurate and reliable tools for multiple sequence alignment and phylogeny reconstruction. Unfortunately, current existing tools are unreliable and are prone to serious errors when applied to large and divergent biological sequences. The success of this project will not only make significant contribution to the relevant research fields, but also help achieve goals in certain real-life biological research projects which are unique and important to Australia.Read moreRead less
Philanthropy, celebrity and governance in the People's Republic of China. The project is the first major study of the new phenomenon of celebrity philanthropy and its governance in present-day China. It will provide knowledge of government and philanthropic responses to some of the problems associated with unequal development in China and increase Australians' capacity to engage effectively with a rapidly changing China.