Renal Artery Denervation Performed With Noncontact Circumferential Endovascular Ablation Using A Novel Microwave Catheter
Funder
National Health and Medical Research Council
Funding Amount
$90,967.00
Summary
High blood pressure is a common medical condition leading to death and disability. Some people with high blood pressure do not respond to medical treatment due to abnormal signals from the kidneys that tell the body to increase the blood pressure. We have designed a microwave catheter that can be placed inside the kidney artery and used to heat the kidney nerves around it to stop the relay of these messages. This will lower blood pressure for people who cannot control it with medications alone.
Molecular Basis For Female Age-associated Decline In Oocyte Quality And Fertility
Funder
National Health and Medical Research Council
Funding Amount
$71,792.00
Summary
Many women cannot have children because of suboptimal egg quality, often due to ageing. In order for novel strategies to be developed for improving egg quality, it will first be important to understand how key factors in eggs are regulated. This project will use state-of-the-art techniques to interrogate a pivotal pathway we have discovered in eggs that could be responsible for age-related decline and could hold the key to new approaches for rejuvenating eggs.
An Exploration Of Cerebral Palsy Aetiology: Assisted Reproductive Technology And Congenital Anomalies
Funder
National Health and Medical Research Council
Funding Amount
$89,420.00
Summary
Cerebral palsy (CP) is the most common physical disability of childhood, describing a group of permanent disorders of movement caused by damage to the developing brain. The causes of CP are poorly understood for most people. This study will explore and quantify the impact of two known risk factors on CP: assisted reproductive technology and congenital anomalies. When these causes of CP are better understood, possibilities for prevention of this disability can be sought.
An Integrated EHealth Strategy To Optimise Outpatient Disease & Psychological Management In Inflammatory Bowel Disease
Funder
National Health and Medical Research Council
Funding Amount
$122,533.00
Summary
Inflammatory bowel disease (IBD) affects many Australians. We will undertake a prospective study comparing standard IBD clinic outpatient management with a technology enabled self management (eHealth) platform for patients with mild to moderate IBD in relation to disease activity, medication status, psychological distress and quality of life. Patients in the eHealth intervention arm will be stratified according to risk and treated via algorithms according to standardised evidence-based medicine.
Evaluating A Weight Gain Prevention Study In Rural Australian Women
Funder
National Health and Medical Research Council
Funding Amount
$87,290.00
Summary
Overweight and obesity are crucial health issues worldwide with the prevalence estimated at 1.5 billion. In Australia 34% of women aged 26-31 years are overweight or obese and women living in rural communities are gaining weight faster than urban dwelling women. The work undertaken in this PhD will comprehensively evaluate and assist in the implementation of a large cluster randomized control trial testing the effectiveness of a low intensity, healthy lifestyle intervention to prevent weight gai ....Overweight and obesity are crucial health issues worldwide with the prevalence estimated at 1.5 billion. In Australia 34% of women aged 26-31 years are overweight or obese and women living in rural communities are gaining weight faster than urban dwelling women. The work undertaken in this PhD will comprehensively evaluate and assist in the implementation of a large cluster randomized control trial testing the effectiveness of a low intensity, healthy lifestyle intervention to prevent weight gain in women living in rural Australia.Read moreRead less
Activating Primary Care COPD Patients With Multi-morbidity (APCOM) Pilot Project
Funder
National Health and Medical Research Council
Funding Amount
$78,309.00
Summary
The Activating Primary Care COPD Patients with Multi-morbidity (APCOM) pilot project aims to empower primary care patients with chronic obstructive pulmonary disease and other co-existing chronic conditions. This will be done by means of a tailored, practice nurse-delivered, self-management intervention designed to improve the participants' disease awareness and coping skills.
Why Do People Develop Chronic Low Back Pain? An Investigation Of Brain Function As A Predictor Of Chronic Low Back Pain.
Funder
National Health and Medical Research Council
Funding Amount
$96,631.00
Summary
Chronic low back pain is the most disabling condition worldwide. Two objective measures of brain function, electrical signals of brain activity (electroencephalography), and attentional bias observed with eye tracking technology will be measured in a group of participants with acute back pain. These measurements will provide objective markers of brain function that may be predictive of the transition from acute to chronic low back pain, providing new opportunities for treatment.
Individualizing Cytomegalovirus Preventative Strategies Following Solid Organ Transplantation: A Precision Medicine Approach
Funder
National Health and Medical Research Council
Funding Amount
$128,224.00
Summary
Cytomegalovirus (CMV) infection is a significant contributor to poor outcomes following solid organ transplantation. Current preventative strategies are somewhat effective but treat groups of patients similarly rather than targeting the individual, so many patients are treated unnecessarily & breakthrough disease still occurs. We propose a program of research directed towards individualizing CMV prevention strategies in solid organ transplant recipients, incorporating new diagnostic tests.
An Exploration Of The Mechanisms Underlying A Novel Pain Biology Education Intervention (Explain Pain) In Reducing The Development Of Chronic Low Back Pain
Funder
National Health and Medical Research Council
Funding Amount
$106,057.00
Summary
Chronic low back pain is a massive health problem in Australia. This research will investigate the underlying mechanisms of modulating one’s thoughts and beliefs about their pain via a psychoeducative intervention after an acute episode of low back pain. Exploring the mechanisms of this intervention is a crucial step towards understanding how explaining pain could reduce the development of chronic low back pain from an acute episode of low back pain.
A Prospective Investigation Of Musculoskeletal And Vestibular Deficits Post-concussion In Adolescent Rugby Players
Funder
National Health and Medical Research Council
Funding Amount
$66,746.00
Summary
The primary aim of this thesis will be to investigate deficits in the musculoskeletal and vestibular systems in the acute and subacute periods following sport-related concussion injury in school level rugby union players.