AusDiab 3: Emerging Risk Factors For And Long-term Incidence Of Cardio-metabolic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,616,397.00
Summary
This study will track 11,000 Australian adults over 12 years to determine how many develop diabetes, obesity, kidney and heart disease. The study will develop ways to best predict those who are going to develop these conditions before they have arisen, and will explore a range of novel risk factors to better understand these conditions.
Top-down rehydration: role of multiple water sources in mangrove function. This project aims to combine cutting-edge analytical and imaging techniques to assess contributions of atmospheric water sources to shoot-water balances, identify leaf traits associated with top-down rehydration, and determine the relative importance of different sources of water used by mangroves in maintenance of photosynthetic carbon assimilation along natural gradients in salinity and aridity. The capacity of shoots ....Top-down rehydration: role of multiple water sources in mangrove function. This project aims to combine cutting-edge analytical and imaging techniques to assess contributions of atmospheric water sources to shoot-water balances, identify leaf traits associated with top-down rehydration, and determine the relative importance of different sources of water used by mangroves in maintenance of photosynthetic carbon assimilation along natural gradients in salinity and aridity. The capacity of shoots to absorb atmospheric water could profoundly affect the diversity, survival and productivity of mangroves where high soil salinity limits water uptake by roots, particularly during hot, dry conditions.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH130200013
Funder
Australian Research Council
Funding Amount
$4,979,922.00
Summary
ARC Research Hub for advanced breeding to transform prawn aquaculture. ARC Research Hub for advanced breeding to transform prawn aquaculture. This Research Hub aims to bring together world-leading animal geneticists, research and service providers, and Australia's largest prawn farm to gather the genomic resources, commercial phenotypic data, and apply cutting-edge genetic and genomic selection methodologies, leading to the transformative improvement program for a black tiger prawn aquaculture s ....ARC Research Hub for advanced breeding to transform prawn aquaculture. ARC Research Hub for advanced breeding to transform prawn aquaculture. This Research Hub aims to bring together world-leading animal geneticists, research and service providers, and Australia's largest prawn farm to gather the genomic resources, commercial phenotypic data, and apply cutting-edge genetic and genomic selection methodologies, leading to the transformative improvement program for a black tiger prawn aquaculture species globally.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100206
Funder
Australian Research Council
Funding Amount
$550,000.00
Summary
Lattice light sheet microscopy for imaging biology in real space and time. This project aims to establish a Lattice Light-Sheet Microscope (LLSM) Facility, to provide the dedicated computing infrastructure needed for terabyte-scale image acquisition and handling. Lattice light sheet microscopy allows four-dimensional imaging of live biological specimens from individual molecules to small organisms. The microscope images live specimens without phototoxicity or photobleaching, enabling prolonged i ....Lattice light sheet microscopy for imaging biology in real space and time. This project aims to establish a Lattice Light-Sheet Microscope (LLSM) Facility, to provide the dedicated computing infrastructure needed for terabyte-scale image acquisition and handling. Lattice light sheet microscopy allows four-dimensional imaging of live biological specimens from individual molecules to small organisms. The microscope images live specimens without phototoxicity or photobleaching, enabling prolonged imaging of significant physiological or biophysical events. Expected outcomes include high impact discoveries and publications in fundamental research, rapid solutions for industry-focussed projects and opportunities for collaboration, research and development. The imaging is expected to reveal key scientific insights and showcase biology to the public.Read moreRead less
ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory ne ....ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory networks and to address how environmental factors impinge on these regulatory networks. The formation of this National Research Network is unique, timely and strategic. It will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
Reducing Prolonged Workplace Sitting Time In Office Workers: A Cluster-randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$524,613.00
Summary
Groundbreaking Australian research shows that sitting for too long, which is routine for most office workers, contributes to overweight and to a greater risk of developing diabetes and heart disease. In over 300 desk-bound office workers, this world-first study will assess the effectiveness of an innovative workplace program aimed at reducing and breaking up sitting time. It will identify practical ways for Australian office workers to minimise unhealthy effects of sitting too much at work.
A Multi-setting Intervention To Reduce Sedentary Behaviour, Promote Physical Activity And Improve Childrens Health
Funder
National Health and Medical Research Council
Funding Amount
$860,343.00
Summary
Sedentary behaviours and physical inactivity play a major role in the rising prevalence of obesity among children in Australia. This intervention study will take place in the school and family settings which play a critical role in shaping children's health behaviours. The objective is to determine whether a 2-year behavioural intervention reduces sedentary behaviour and promotes physical activity and results in improved health among 8-9 year old children.
Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or t ....Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or the acute exacerbation of existing disease. The impact of these new technologies on the early diagnosis and improved triaging of patients in emergency departments is potentially profound and could result in improved healthcare outcomes for the patients and reduced admissions to hospital as well as the development of a substantial international market.Read moreRead less
Unsaturation of vapour pressure inside leaves: fundamental, but unknown. This project aims to determine when and to what extent the air inside leaves becomes unsaturated with water vapour. All current interpretation and modelling of leaf gas exchange assumes saturation under all circumstances. Compelling evidence has been obtained that suggests this is not true under moderate air vapour pressure deficits. A novel technique will be employed to assess the water vapour concentration of the air insi ....Unsaturation of vapour pressure inside leaves: fundamental, but unknown. This project aims to determine when and to what extent the air inside leaves becomes unsaturated with water vapour. All current interpretation and modelling of leaf gas exchange assumes saturation under all circumstances. Compelling evidence has been obtained that suggests this is not true under moderate air vapour pressure deficits. A novel technique will be employed to assess the water vapour concentration of the air inside leaves based on stable isotope analysis of carbon dioxide and water vapour exchanged between leaves and air. The project is expected to provide fundamental knowledge about how stomata regulate photosynthesis and water use, with significant implications for modelling vegetation function and for improving the performance of crop plants.Read moreRead less
ARC Australia-New Zealand Research Network for Vegetation Function. Plant species vary widely in quantitative functional traits, and in their relations to climate, soils and geography. Global generalizations are emerging. Vegetation Function network will reach from plant function into genomics and crop breeding, into palaeoecology and vegetation history, into landscape management for carbon, water and salinity outcomes, into forecasting future ecosystems under global change, and into phylogeny, ....ARC Australia-New Zealand Research Network for Vegetation Function. Plant species vary widely in quantitative functional traits, and in their relations to climate, soils and geography. Global generalizations are emerging. Vegetation Function network will reach from plant function into genomics and crop breeding, into palaeoecology and vegetation history, into landscape management for carbon, water and salinity outcomes, into forecasting future ecosystems under global change, and into phylogeny, ecoinformatics and evolutionary theory. Across this span, working groups will target nine identified opportunities for breakthrough research. Each research target needs input from two or more disciplines. Together, the nine targets link across disciplines, as a network that spans from genomic to planetary scales.Read moreRead less