Glucose is a critical fuel for living organisms and its presence in the gut triggers nerves that slow stomach emptying. However, little is known of how glucose is actually detected in the gut. We have established that sweet taste molecules of the tongue are also present in the gut, where they may detect glucose. This research will measure the expression and function of these molecules in the gut of humans and mice, and reveal key information on their potential as targets in health and disease.
Technological innovation and change in supply chain integration. In examining emerging technology that can transform the performance of Australian industry we address the following priority goals: better understanding the processes that will advance knowledge and facilitate the development of technological innovations; the potential application of Radio Frequency Identification (RFID) technologies across an entire supply chain; and the improved management of information in the storage, distribut ....Technological innovation and change in supply chain integration. In examining emerging technology that can transform the performance of Australian industry we address the following priority goals: better understanding the processes that will advance knowledge and facilitate the development of technological innovations; the potential application of Radio Frequency Identification (RFID) technologies across an entire supply chain; and the improved management of information in the storage, distribution, and delivery of products (smart information use). Improvement in the operational efficiency and performance of the supply chain will increase national wealth while minimising environmental impacts on the environment, for example, through the better utilisation of heavy freight carriers.Read moreRead less
Australian Centre For Research Excellence In Aboriginal Sexual Health And Blood Borne Viruses
Funder
National Health and Medical Research Council
Funding Amount
$2,496,848.00
Summary
Despite efforts to improve sexual health and blood borne virus outcomes for Aboriginal people over the last twenty years, this area lacks national coordination, has critical research gaps and requires a boost of research capacity to address the burden of diseases. This CRE will address research gaps, using novel, multidisciplinary methods and using unique research translation methods to ensure policy and practice benefits from the CRE outcomes.
Industry Laureate Fellowships - Grant ID: IL230100039
Funder
Australian Research Council
Funding Amount
$3,516,522.00
Summary
Aqueous sodium batteries for household and smart-grid electricity storage. This project aims to design and commercialise safe, cost-effective, long-lasting, fast-charging, high energy density aqueous sodium-based batteries to store renewable energy for use in households and smart grids. With a focus on developing and scaling technology and in collaboration with industry partners, the project’s expected outcomes include an enhanced ability to store excess energy and modulate its release into a sm ....Aqueous sodium batteries for household and smart-grid electricity storage. This project aims to design and commercialise safe, cost-effective, long-lasting, fast-charging, high energy density aqueous sodium-based batteries to store renewable energy for use in households and smart grids. With a focus on developing and scaling technology and in collaboration with industry partners, the project’s expected outcomes include an enhanced ability to store excess energy and modulate its release into a smart grid during peak demand. Of benefits to Australia, this project will deliver access to reliable, safe and cheap batteries for smart-grid electricity storage in households and a competitive industry manufacturing capability. The downstream benefit is a reduction in energy costs and a contribution to net-zero emissions.
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Discovery Early Career Researcher Award - Grant ID: DE240100952
Funder
Australian Research Council
Funding Amount
$432,237.00
Summary
Developing aluminium-sulfur batteries with high voltage and low cost. As use of renewable energy sources increases, so too does the need for suitable storage systems for the energy produced. Aluminium-Sulfur (Al-S) batteries provide a reliable energy storage option, but suffer from a low voltage output and despite aluminium and sulfur being two of the world’s most abundant and low-cost materials, other components in batteries are prohibitively expensive. This project aims to address these challe ....Developing aluminium-sulfur batteries with high voltage and low cost. As use of renewable energy sources increases, so too does the need for suitable storage systems for the energy produced. Aluminium-Sulfur (Al-S) batteries provide a reliable energy storage option, but suffer from a low voltage output and despite aluminium and sulfur being two of the world’s most abundant and low-cost materials, other components in batteries are prohibitively expensive. This project aims to address these challenges by designing an Al-S battery technology with efficient electrode materials and low-cost electrolytes, making them both cost effective and capable of high levels of energy storage. The outcome will place Australia as a world leader in battery technology and support our future renewable energy storage needs.Read moreRead less
Folding polymers for high-performance energy storage. This project aims to address the current bottleneck of energy storage capability in polymers by developing new compact structures through programmed polymer folding. This project expects to understand how structures determine electrochemistry properties by creating densely packed redox-active polymers to break the limits of charge transfer rates and storage ability. Expected outcomes include deep insights into fundamental electrochemical reac ....Folding polymers for high-performance energy storage. This project aims to address the current bottleneck of energy storage capability in polymers by developing new compact structures through programmed polymer folding. This project expects to understand how structures determine electrochemistry properties by creating densely packed redox-active polymers to break the limits of charge transfer rates and storage ability. Expected outcomes include deep insights into fundamental electrochemical reaction mechanisms, laying a strong foundation for the applications of polymers from flexible electronic devices to micro-grid energy storage. This project should provide significant benefit in new knowledge and support advanced manufacturing using our high value-added materials.Read moreRead less
Characterisation of the oxygen-sensing asparaginyl hydroxylase, FIH-1, and hydroxylase-specific antagonists. This research will provide fundamental information on how cells and whole organisms can sense and respond accordingly to oxygen deficiency. This information is fundamental for our understanding of embryo development and adult life in different environments, and central to the diagnosis and treatment of diseases such as stroke, cardiovascular disease, and cancer. This research will contrib ....Characterisation of the oxygen-sensing asparaginyl hydroxylase, FIH-1, and hydroxylase-specific antagonists. This research will provide fundamental information on how cells and whole organisms can sense and respond accordingly to oxygen deficiency. This information is fundamental for our understanding of embryo development and adult life in different environments, and central to the diagnosis and treatment of diseases such as stroke, cardiovascular disease, and cancer. This research will contribute to our basic knowledge of these processes, provide invaluable information about the specific genes and proteins involved, and provide direct information about the therapeutic potential of specific drugs or inhibitors designed to target this oxygen response in human disease.Read moreRead less
Low cost aqueous rechargeable zinc batteries for grid-scale energy storage. This project aims to advance energy storage technology by developing high energy aqueous rechargeable zinc batteries, which are the most promising choice for large-scale electrical energy storage, in particular for smart electric grids, owing to their low cost, high safety, and eco-friendly features. The success of this project will advance our fundamental understanding of aqueous rechargeable batteries, provide techniqu ....Low cost aqueous rechargeable zinc batteries for grid-scale energy storage. This project aims to advance energy storage technology by developing high energy aqueous rechargeable zinc batteries, which are the most promising choice for large-scale electrical energy storage, in particular for smart electric grids, owing to their low cost, high safety, and eco-friendly features. The success of this project will advance our fundamental understanding of aqueous rechargeable batteries, provide techniques for the development of a low-cost, high energy, and long life system for renewable energy storage, and benefit Australia's environment, economy, and sustainability.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101011
Funder
Australian Research Council
Funding Amount
$420,818.00
Summary
Developing advanced potassium-sulfur batteries for scalable energy storage. Potassium-sulfur (K-S) batteries are recognised as a promising energy storage technology for large-scale applications, due to their high theoretical capacity, low toxicity and the low cost of both potassium and sulfur. However, their grid-scale development is plagued by safety hazards and fast capacity fade. This project aims to address these challenges by developing atomic-level engineering of host materials for sulfur, ....Developing advanced potassium-sulfur batteries for scalable energy storage. Potassium-sulfur (K-S) batteries are recognised as a promising energy storage technology for large-scale applications, due to their high theoretical capacity, low toxicity and the low cost of both potassium and sulfur. However, their grid-scale development is plagued by safety hazards and fast capacity fade. This project aims to address these challenges by developing atomic-level engineering of host materials for sulfur, K metal anode and solid electrolyte. The outcomes of this project will provide increased understanding of the mechanism for K-S batteries and novel strategies for their development, placing Australia at the forefront of K-S batteries for scalable battery research and supporting our cutting-edge energy storage technology.
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Defining how molecular switches program cell identity during development. Aims: This project aims to investigate how molecular switches known as transcription factors, work together to turn genes on or off to program cell identity during development.
Significance: This project expects to generate new knowledge in the area of genetics and developmental biology using collaborative, cutting edge technologies.
Outcomes: Expected outcomes of this project include the identification of new genes impor ....Defining how molecular switches program cell identity during development. Aims: This project aims to investigate how molecular switches known as transcription factors, work together to turn genes on or off to program cell identity during development.
Significance: This project expects to generate new knowledge in the area of genetics and developmental biology using collaborative, cutting edge technologies.
Outcomes: Expected outcomes of this project include the identification of new genes important for programming the identity of cells that comprise our blood vessels, lymphatic vessels and circulating blood cells.
Benefits: Data generated will underpin the development of approaches to program/reprogram stem cells to produce mature cells for transplantation or tissue engineering purposes ex vivo.Read moreRead less