Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.
Synthetic storage for improving flexibility and security of micro-grids. This project aims to remove the need for energy storage in micro-grids via adoption of synthetic storage. Micro-grids encounter high renewable energy penetrations early, given their small size. Typically, micro-grid variability is managed with technologies such as energy storage. Synthetic storage involves replacing fixed speed diesel assets with variable speed diesel technology. This project offers a cost-effective way to ....Synthetic storage for improving flexibility and security of micro-grids. This project aims to remove the need for energy storage in micro-grids via adoption of synthetic storage. Micro-grids encounter high renewable energy penetrations early, given their small size. Typically, micro-grid variability is managed with technologies such as energy storage. Synthetic storage involves replacing fixed speed diesel assets with variable speed diesel technology. This project offers a cost-effective way to improve renewable penetration and reduce diesel fuel consumption in micro-grids by removing the need for expensive energy storage. The expected project outcomes include reductions in cost and complexity for high renewable energy penetration micro-grids, reduced emissions and improved micro-grid reliability.Read moreRead less
Investigating the molecular function of alpha-Haemoglobin stabilising protein. The research described in this proposal will provide new insights into haemoglobin regulation and redox chemistry in erythrocytes. Deregulation of these processes gives rise to a number of debilitating diseases, including varieties of anaemia and thalassaemia-in Australia it is estimated that 3% of the population could be carriers of b-thalassaemia mutations. Given the contribution of free aHb to the pathology of b-th ....Investigating the molecular function of alpha-Haemoglobin stabilising protein. The research described in this proposal will provide new insights into haemoglobin regulation and redox chemistry in erythrocytes. Deregulation of these processes gives rise to a number of debilitating diseases, including varieties of anaemia and thalassaemia-in Australia it is estimated that 3% of the population could be carriers of b-thalassaemia mutations. Given the contribution of free aHb to the pathology of b-thalassaemia, understanding the specific aHb-binding factor, AHSP is a goal of national significance. In the long term, manipulation of AHSP function through gene therapy may have a direct role in the treatment of thalassaemia.Read moreRead less
No load diesel application in remote power systems. No load diesel application in remote power systems. This project aims to investigate and optimise no-load diesel application within remote area renewable hybrid power systems. While hundreds of remote Australian communities rely on expensive diesel for power generation, this project intends to increase penetration of alternative renewable sources into remote and isolated power systems. Using dual thermodynamic and electrical modelling, this pro ....No load diesel application in remote power systems. No load diesel application in remote power systems. This project aims to investigate and optimise no-load diesel application within remote area renewable hybrid power systems. While hundreds of remote Australian communities rely on expensive diesel for power generation, this project intends to increase penetration of alternative renewable sources into remote and isolated power systems. Using dual thermodynamic and electrical modelling, this project will investigate low to no-load diesel threshold capability, reducing diesel consumption at minimal costs. The project is expected to return immediate benefits to remote mining, defence and tourism based communities, providing a pathway to reduced diesel usage and increased renewable penetration.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less