Supply, Demand And The Distribution Of Health Services In Australia
Funder
National Health and Medical Research Council
Funding Amount
$308,038.00
Summary
The distribution of medical services and its impact on access and equity is widely recognised as a key concern of the Australian community. Access and equity are key indicators to the public of the performance of a health system. These concerns have led to the adoption of major policy goals under Medicare relating to equitable access to medical services for the population as a whole. Furthermore, both the community and policy makers have expressed high levels of concern over the distribution of ....The distribution of medical services and its impact on access and equity is widely recognised as a key concern of the Australian community. Access and equity are key indicators to the public of the performance of a health system. These concerns have led to the adoption of major policy goals under Medicare relating to equitable access to medical services for the population as a whole. Furthermore, both the community and policy makers have expressed high levels of concern over the distribution of medical services between sub-markets and sub-populations, in particular, in the distribution of medical services between urban and rural-remote areas. This project, for the first time, comprehensively examines the performance of Medicare in terms of access to medical services over time. Australian data sets, largely untapped by economic modelling, will be used for analysis of the relationships between the distribution of, access to, and demand and fees for Australian medical services and their impact upon mortality over time. The study will result in the first comprehensive Australian description of access and supply of different medical services by social group and by geographic location over time. Furthermore it will provide evidence on the key determinants of distribution and changes in the distribution of medical services and estimates the likely effects of policy instruments designed to address the distribution of, and access to, medical services.Read moreRead less
An explainability oriented approach to manage dependent supply chain risks. This project aims to help supply chain companies model the impact on their operations by capturing the uncertainties impacting their upstream suppliers. In the current uncertain business environment, the project's outcome will benefit service-based industries to have an enhanced understanding of their operating environment and take decisions accordingly to avoid failures. This will significantly increase the productivity ....An explainability oriented approach to manage dependent supply chain risks. This project aims to help supply chain companies model the impact on their operations by capturing the uncertainties impacting their upstream suppliers. In the current uncertain business environment, the project's outcome will benefit service-based industries to have an enhanced understanding of their operating environment and take decisions accordingly to avoid failures. This will significantly increase the productivity of Australian service-based industries across different domains. The expected outcome is that it generates new knowledge by which risk managers of a focal company can conjointly consider risk identification/assessment with risk management analysis to develop explainable strategies for managing uncertainties. Read moreRead less
Evolution And Function Of A Novel Lateral Flagellar Locus, Flag-2, In Pathogenic Escherichia Coli
Funder
National Health and Medical Research Council
Funding Amount
$465,158.00
Summary
This project will study how the bacteria that cause infant diarrhoea colonize the intestine and induce disease. We have identified a novel genetic region that allows E. coli to survive and persist in the intestine. Similar genes are also present in closely related organisms. This project will help us to undestand how new diseases evolve and emerge and may lead to the development of new vaccines to protect against infant diarrhoea.
Advancing the theoretical bases of supply chain management through the lens of relational exchange theory. This project will explain and predict the behaviour of supply chain members better than current theories do. An integrated theory of supply chain management will be developed and tested empirically. This theory will enable better understanding of how supply chains function and guide actions of managers so that the expected benefits are realised.
Barrett's oesophagus (BO) is a condition that arises in some patients with chronic reflux (heartburn) and increases the risk of developing cancer of the oesophagus. However, the exact mechanisms involved in its development are unknown. This project aims to investigate how a protein called sonic hedgehog might be involved using novel cell culturing techniques that allow us to model the growth of oesophageal tissue in the laboratory. This could lead to development of new therapies for treating BO.
Synchromodal container logistics for Australia. Synchromodal container logistics for Australia. This project aims to develop advanced mathematical optimization models and algorithms to create multi-modal logistics approaches for container movements in and out of Australia’s busy ports. The increasingly congested capital cities of Sydney, Brisbane and Melbourne need to find new ways of moving an increasing volume of containerized freight. Moving from trucks to rail is expected to reduce pollution ....Synchromodal container logistics for Australia. Synchromodal container logistics for Australia. This project aims to develop advanced mathematical optimization models and algorithms to create multi-modal logistics approaches for container movements in and out of Australia’s busy ports. The increasingly congested capital cities of Sydney, Brisbane and Melbourne need to find new ways of moving an increasing volume of containerized freight. Moving from trucks to rail is expected to reduce pollution and road congestion, but is only possible if highly efficient modes of operation can be developed. Research into system design and operational scheduling is expected to achieve the required efficiency for multi-modal logistics that will reduce air pollution and road congestion.Read moreRead less
Characterisation Of Human Embryonic Stem Cell Differentiation To Haematopoietic Progenitors And Stem Cells
Funder
National Health and Medical Research Council
Funding Amount
$638,856.00
Summary
Blood stem cells, which are found in the bone marrow, are currently used for treating human blood disorders including leukemia and lymphoma. However, for the majority of bone marrow transplant candidates, suitable donors cannot be found. Using embryonic stem cells, this project aims to define the conditions required to generate blood stem cells in the laboratory. The aim of the work is to provide a new source of blood stem cells that could be used in place of donor derived bone marrow.
Simulating And Stimulating The Blood-Brain-Barrier: A Platform For Investigating Non-pharmaceutical Alzheimer's Therapy
Funder
National Health and Medical Research Council
Funding Amount
$680,758.00
Summary
Alzheimer's disease is a looming public health threat worldwide. Despite the widespread acknowledgement of this issue, there are a lack of effective drugs that can slow disease progression. This project aims to investigate a new class of non-pharmaceutical treatment methods based on controlled acoustic, electrical and optical stimulation methods to treat and reverse the base causes of Alzheimer's disease.
Modelling Of Clinic And Ambulatory Blood Pressure On Cardiovascular Risk And Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$133,957.00
Summary
Whilst ambulatory blood pressure monitoring data has been shown to be a good predictor of cardiovascular events, there remains controversy as to its utility in clinical practice. This project will use data from existing population and clinical cohort studies to examine the role of ambulatory blood pressure in risk assessment and hypertension management in Australia and around the globe. The findings are likely to have a major impact on clinical guidelines for hypertension management.
Understanding The Origins Of Neurogenic Hypertension
Funder
National Health and Medical Research Council
Funding Amount
$668,914.00
Summary
Brain cells that control the cardiovascular system are thought to have stopped dividing by adulthood. We recently discovered that this is not the case. Our initial findings suggest that these nascent cells might be important for maintaining normal blood pressure. This work will allow us to elucidate the function of these nascent cells and how they integrate into the circuit that controls the cardiovascular system. Our findings will be fundamental for understanding diseases such as hypertension.