Immigration, technology and literacy: key challenges for language policy in a changing Japan. Australia needs a sophisticated understanding of social and cultural dynamics in a regional partner with whom we have substantial economic, political and cultural relations. This project will problematise current language policy in Japan to take account of important recent areas of social transformation and associated key cultural beliefs about language. It will produce a body of significant individual ....Immigration, technology and literacy: key challenges for language policy in a changing Japan. Australia needs a sophisticated understanding of social and cultural dynamics in a regional partner with whom we have substantial economic, political and cultural relations. This project will problematise current language policy in Japan to take account of important recent areas of social transformation and associated key cultural beliefs about language. It will produce a body of significant individual research and policy recommendations; will bring together high profile international researchers and Japanese policy makers and educators in two collaborative exercises which will strengthen links between the two countries at both academic and government levels; and will launch the research career of a postgraduate student. Read moreRead less
The measurement of primary traits in second language oral proficiency in second language acquisition research. The proposed research will help to inform high-quality learning outcomes for international ESL (English as a Second Language) students and students who study Japanese or Spanish as a second language in Australian universities. Improved effectiveness in current second language teaching pedagogy will result from a deeper understanding of the role that the key language traits (syntactic co ....The measurement of primary traits in second language oral proficiency in second language acquisition research. The proposed research will help to inform high-quality learning outcomes for international ESL (English as a Second Language) students and students who study Japanese or Spanish as a second language in Australian universities. Improved effectiveness in current second language teaching pedagogy will result from a deeper understanding of the role that the key language traits (syntactic complexity, lexical range, accuracy and fluency) play in the attainment of advanced proficiency. Read moreRead less
From musume (daughters) to shojo (girls): representations of young women in modern Japanese literature. This will be the first comprehensive study of the transition of young women from musume (daughters) to shôjo (girls) in modern Japanese literature. Intended as a pioneering study of "girl power literature", it will identify neglected texts and authors, clarify the significant changes in literary representations of young women, and recognise the positive and creative aspects in these representa ....From musume (daughters) to shojo (girls): representations of young women in modern Japanese literature. This will be the first comprehensive study of the transition of young women from musume (daughters) to shôjo (girls) in modern Japanese literature. Intended as a pioneering study of "girl power literature", it will identify neglected texts and authors, clarify the significant changes in literary representations of young women, and recognise the positive and creative aspects in these representations. With its scope covering historical and contemporary, and popular and serious, the project will enhance Australia's understanding of Japanese literature, culture, and society. It will also be beneficial to studies of women, children, and adolescence in other communities including Australia.Read moreRead less
Local Culture/Global Space: Japanese Minority Sexualities and the Internet. After English (43%), Japanese (9%)is the most used language on the Internet. No study has addressed the specific ways in which Japanese language use affects Internet communication or how the Internet is being used by minoritised groups and individuals. The project will examine Internet use by minority sexualities in Japan in order to ascertain how individuals and communities who fall outside the 'mainstream' of society i ....Local Culture/Global Space: Japanese Minority Sexualities and the Internet. After English (43%), Japanese (9%)is the most used language on the Internet. No study has addressed the specific ways in which Japanese language use affects Internet communication or how the Internet is being used by minoritised groups and individuals. The project will examine Internet use by minority sexualities in Japan in order to ascertain how individuals and communities who fall outside the 'mainstream' of society interact with this new technology. The project will contribute to our understanding of how the Internet, a supposedly global medium, also facilitates the emergence of very local subcultures. The project will result in a series of conference presentations, journal papers and a book.Read moreRead less
Arbovirus Activation And Modulation Of NLRP3 Inflammasome
Funder
National Health and Medical Research Council
Funding Amount
$779,720.00
Summary
This project aims to establish how mosquito borne viruses such as Ross River and dengue viruses interacts with the human host to cause disease, including how the virus evades the host’s immune response to persist and cause disease for prolonged periods. Knowing how differences in the virus and the host’s immune system interplay to cause asymptomatic to severely disabling disease will assist in devising new treatments and prevention programs to lessen the impact of these diseases in Australia.
New Insights Into Viral Inflammatory Disease Mechanisms And Approaches To Therapy
Funder
National Health and Medical Research Council
Funding Amount
$631,010.00
Summary
This fellowship aims to establish how viruses cause disease, including how they evade the immune response to persist and cause disease for prolonged periods. My vision is that knowing how the virus and the immune system interact to determine disease severity will assist in devising new treatments and prevention programs to lessen the impact of viral diseases in Australia and worldwide.
Mosquito-borne alphaviruses such as Ross River and chikungunya viruses cause widespread epidemics and exert extreme pressure on the public health systems of affected regions. Alphaviruses spreads to joints and triggers a severe disease in those affected. There are no effective treatments or vaccines. The project will investigate virus-host interaction at the bite site. The outcome will be new knowledge to treat infection at the mosquito bite site to prevent joint disease.
Novel Insights Into The Pathobiology Of Alphavirus Infections
Funder
National Health and Medical Research Council
Funding Amount
$827,660.00
Summary
Infections with mosquito-borne viruses are increasing at an alarming rate worldwide. Ross River virus is endemic in parts of Australia, PNG and Pacific islands, while chikungunya virus is distributed globally and causes recurrent pandemics that involve millions of people. These viruses cause severe musculoskeletal disease for several months after infection. This project aims to establish how these viruses interact with the human host to cause disease and may provide a basis for new treatments.
Glycotherapeutics; A New Class Of Treatment For Alphavirus-induced Musculoskeletal Disease
Funder
National Health and Medical Research Council
Funding Amount
$449,868.00
Summary
The hallmark of alphavirus disease is crippling pain and joint arthritis, which often has an extended duration. Currently there is no licenced specific treatment for alphavirus disease and the increasing spread of infection highlights an urgent need for therapeutic intervention strategies. This grant looks at the potential of pentosan polysulfate as a promising drug-repurposing candidate for the treatment of alphavirus-induced arthritis.
The Role Of Innate Inflammatory Responses In Viral Arthritis
Funder
National Health and Medical Research Council
Funding Amount
$782,514.00
Summary
Viruses are known to cause arthritis (HIV, hepatitis viruses, mosquito borne viruses). Symptoms of viral arthritis include joint pain, stiffness, and swelling. The mechanism of disease is poorly understood. We have developed a novel animal model of disease and human cell culture models by which to study disease caused by viral infections. This models provide an excellent opportunity to explore the mechanisms of rheumatic disease in a functioning animal and to explore new treatment regimes.