Towards knowledge discovery from imperfect and evolving data. Information extraction from data is critical, both to analyse and protect consumer data. However, many learning techniques are developed using perfect, static datasets, quite different to messy, ever-changing real-world data. This project aims to develop data analytics techniques that can extract accurate information in complex structures from imperfect/incomplete data that changes over time. Expected outcomes are a prototype tool, te ....Towards knowledge discovery from imperfect and evolving data. Information extraction from data is critical, both to analyse and protect consumer data. However, many learning techniques are developed using perfect, static datasets, quite different to messy, ever-changing real-world data. This project aims to develop data analytics techniques that can extract accurate information in complex structures from imperfect/incomplete data that changes over time. Expected outcomes are a prototype tool, tested on real datasets, that combines new techniques in data modelling, algorithm development, and system design. Likely benefits are enhanced Australia's competence in data science through student training and new, robust data tools relevant to critical sectors such as cybersecurity, healthcare, and defence.Read moreRead less
Engineering nanomembranes for Long-term Implanted Flexible Electronics. This project aims to investigate the key technologies of inorganic semiconductor nanomembranes for long-lived bio-integrated electronics. Taking advantage of the well-established silicon carbide (SiC) synthesis and fabrication technology, the project expects to elucidate a new understanding of the SiC-on-polymer platform, establishing a foundational guideline for the development of chemically inert and mechanically flexible ....Engineering nanomembranes for Long-term Implanted Flexible Electronics. This project aims to investigate the key technologies of inorganic semiconductor nanomembranes for long-lived bio-integrated electronics. Taking advantage of the well-established silicon carbide (SiC) synthesis and fabrication technology, the project expects to elucidate a new understanding of the SiC-on-polymer platform, establishing a foundational guideline for the development of chemically inert and mechanically flexible devices. These findings will offer innovative solutions for daunting challenges in bio-integrated electronics, leveraging their safety, reliability, and long-term performance. The project expects to offer Australia cutting edge technologies and an impact profile in the fast-growing flexible bio-electronics market.Read moreRead less
Closing the loop between salience and brain activity. This project aims to understand how animals exposed to an abundance of highly complex information decide what to attend to, that is, how they determine visual saliency. The project will approach this question by systematically tracking visual decision-making in the smallest animal brains, in closed-loop virtual reality environment. This approach will uncover basic working principles applicable to any system that needs to pay attention in a vi ....Closing the loop between salience and brain activity. This project aims to understand how animals exposed to an abundance of highly complex information decide what to attend to, that is, how they determine visual saliency. The project will approach this question by systematically tracking visual decision-making in the smallest animal brains, in closed-loop virtual reality environment. This approach will uncover basic working principles applicable to any system that needs to pay attention in a visually cluttered world, from insects to humans or autonomous vehicles.Read moreRead less
Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn ....Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.Read moreRead less
A Novel Geometric Approach to Shocks in Reaction-Nonlinear Diffusion Models. Reaction-nonlinear diffusion models play a vital role in the study of cell migration and population dynamics. However, the presence of aggregation, or backward diffusion, leads to the formation of shock waves - distinct, sharp interfaces between different populations of densities of cells - and the breakdown of the model. This project will develop new geometric methods to explain the formation and temporal evolution of ....A Novel Geometric Approach to Shocks in Reaction-Nonlinear Diffusion Models. Reaction-nonlinear diffusion models play a vital role in the study of cell migration and population dynamics. However, the presence of aggregation, or backward diffusion, leads to the formation of shock waves - distinct, sharp interfaces between different populations of densities of cells - and the breakdown of the model. This project will develop new geometric methods to explain the formation and temporal evolution of these shock waves, while simultaneously unifying existing regularisation techniques under a single, geometric banner. It will devise innovative tools in singular perturbation theory and stability analysis that will identify key parameters in the creation of shock waves, as well as their dynamic behaviour.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100238
Funder
Australian Research Council
Funding Amount
$426,087.00
Summary
Integrated silicon carbide nanosensors for monitoring extreme environment. This project aims to develop a highly sensitive and reliable sensing platform for structural health monitoring in harsh environments, encompassing high temperature, corrosion, and shock. These conditions have been posing several technical challenges to sensing and electronic devices. The project elucidates the piezoresistive and thermoresistive effects in silicon carbide nanowires, which are the building blocks of robust ....Integrated silicon carbide nanosensors for monitoring extreme environment. This project aims to develop a highly sensitive and reliable sensing platform for structural health monitoring in harsh environments, encompassing high temperature, corrosion, and shock. These conditions have been posing several technical challenges to sensing and electronic devices. The project elucidates the piezoresistive and thermoresistive effects in silicon carbide nanowires, which are the building blocks of robust mechanical and thermal sensors used in extreme conditions. The findings from this project expect to provide Australia with the cutting-edge expertise necessary for developing next-generation monitoring systems in the extreme environments of the oil/gas transportation, mining, automobile, and space exploration industries.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC180100024
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, internatio ....ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.
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Special Research Initiatives - Grant ID: SR0354693
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Australian e-Research Grid. The e-Research Grid program will research and implement core Grid technologies on APAC and partner's deployed HPC resources, to underpin a broad range of Australian research. The computer science CIs will form collaborative links with international programs, adapting developments to local circumstances. The applications-domain CIs will leverage those into their scientific simulations and databases, using grid integrative techniques and portals. Many CIs participate in ....Australian e-Research Grid. The e-Research Grid program will research and implement core Grid technologies on APAC and partner's deployed HPC resources, to underpin a broad range of Australian research. The computer science CIs will form collaborative links with international programs, adapting developments to local circumstances. The applications-domain CIs will leverage those into their scientific simulations and databases, using grid integrative techniques and portals. Many CIs participate in other RNs linking to their motivating applications, enhancing prospects for research and integration. They participate in the APAC Grid program, leveraging 75 HPC staff nationally. A key aim is interoperability with "real-world Grids": eg e-learning & e-health programs.Read moreRead less
Developing an integrated device for on-farm detection of sugarcane diseases. Pathogenic organisms cause yield losses of more than $150M pa to the Australian sugarcane industry and many millions more worldwide. Partnering with Sugar Research Australia, this project aims to develop a novel on-farm diagnostic device, comprising new nanotechnology and magnetism-induced microfluidics with naked eye observation and electrochemical detection. This device is expected to enable improved disease managemen ....Developing an integrated device for on-farm detection of sugarcane diseases. Pathogenic organisms cause yield losses of more than $150M pa to the Australian sugarcane industry and many millions more worldwide. Partnering with Sugar Research Australia, this project aims to develop a novel on-farm diagnostic device, comprising new nanotechnology and magnetism-induced microfluidics with naked eye observation and electrochemical detection. This device is expected to enable improved disease management strategies through the prediction of potential risks and rapid and effective actions to mitigate impending yield loss. In turn productivity and sustainability of Australia’s sugar industry will be enhanced. The new platform device has great potential for improved disease management in other crops in Australia and globally.Read moreRead less
ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. The ARC Centre for the Mathematical Analysis of Cellular Systems aims to deliver the mathematics required to compute life. The Centre will deliver innovation in computational and mathematical biology and establish in silico biology alongside in vivo and in vitro biology. These models will allow us to understand the complexity of life at the cellu ....ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. The ARC Centre for the Mathematical Analysis of Cellular Systems aims to deliver the mathematics required to compute life. The Centre will deliver innovation in computational and mathematical biology and establish in silico biology alongside in vivo and in vitro biology. These models will allow us to understand the complexity of life at the cellular level and enable new ways of combining diverse and heterogenous data. This will allow us to understand the mechanisms underlying cellular behaviour, and to apply rational design engineering methods in order to control the dynamics of biological systems. Read moreRead less