Energy Transitions, Air Pollution And Health In Australia
Funder
National Health and Medical Research Council
Funding Amount
$2,491,229.00
Summary
Emissions from burning biomass (including fossil fuels) are major features of our environment and are the 4th leading global risk factor for premature death. As countries shift their patterns of energy use in response to global warming, new challenges are emerging. Understanding this is crucial to our ability to maintain health and stability in uncertain times. This CRE will examine the health consequences of (1) fossil fuel combustion, (2) landscape fires and (3) alternatives to fossil fuels.
Understanding The Connections Between Aboriginal And Torres Strait Islander Culture, Health And Wellbeing To Support Action To Improve Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$1,915,802.00
Summary
Little is known about the inter-relationship of cultural factors and Aboriginal and Torres Strait Islander health outcomes and these relationships have not been quantified. Through a large cohort study, this research will produce data that combines standard health measures with newly developed quantitative measures of cultural factors, supported by data linkage infrastructure. Robust analytical methods will be used to inform policy and program development.
Glaucoma is the second leading cause of blindness in the world affecting approximately 70 million people. Glaucoma can occur at any age but the commonest type occurs in middle to old age. The disease has a genetic basis and can be inherited. As a result we have been studying the genetics of the disease in two large families from Tasmania. We hope to identify the genes involved in disease causation using a number of genetic techniques. Once mutations in a disease gene have been identified from af ....Glaucoma is the second leading cause of blindness in the world affecting approximately 70 million people. Glaucoma can occur at any age but the commonest type occurs in middle to old age. The disease has a genetic basis and can be inherited. As a result we have been studying the genetics of the disease in two large families from Tasmania. We hope to identify the genes involved in disease causation using a number of genetic techniques. Once mutations in a disease gene have been identified from affected individuals we will then be in a position to look for mutations in other family members and identify those individuals at risk of developing disease. Improvements in our understanding of how these genes are involved in disease causation will allow us to offer diagnostic testing to the wider community and develop better therapeutic interventions for treatment.Read moreRead less
Identification Of Glaucoma Susceptibility Variants By Exome Sequencing In Extended Pedigrees Showing Prior Evidence Of Gene Segregation.
Funder
National Health and Medical Research Council
Funding Amount
$694,002.00
Summary
Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for tr ....Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for treatment or diagnosis.Read moreRead less
STROKE123: A Collaborative, National Effort To Monitor, Promote And Improve The Quality Of Stroke Care In Hospitals And Patient Outcomes.
Funder
National Health and Medical Research Council
Funding Amount
$1,261,292.00
Summary
Stroke is a major public health issue in Australia. This Better Health Initiative partnership project is designed to rigorously evaluate a methodology to improve the monitoring and use of data for stroke, as well as an intervention to address evidence-practice gaps for essential interventions known to have a direct association with patient outcomes. The findings will provide a platform for national roll-out of appropriate and enhanced data collection solutions linked to an effective model for im ....Stroke is a major public health issue in Australia. This Better Health Initiative partnership project is designed to rigorously evaluate a methodology to improve the monitoring and use of data for stroke, as well as an intervention to address evidence-practice gaps for essential interventions known to have a direct association with patient outcomes. The findings will provide a platform for national roll-out of appropriate and enhanced data collection solutions linked to an effective model for improving clinical care and outcomes of stroke.Read moreRead less
Genetic And Functional Analysis Of Brain Malformations
Funder
National Health and Medical Research Council
Funding Amount
$105,327.00
Summary
Disorders of early brain development are recognised as a significant cause of illness and disability in children. Unfortunately, the causes of these conditions are poorly understood, and treatment options are limited. It has become apparent that many of these conditions have an underlying genetic basis. This project will identify genes that regulate brain development and aid the development of improved treatment programs for brain and mind disorders.
Supporting the sustainability of Australia's local news ecosystem. This project aims to understand how Australia’s main public broadcaster, the ABC, can best support public interest journalism in rural and regional communities, with a specific focus on fragile and underserved areas of the nation’s local news ecosystem. The project will develop new knowledge around media power and how news providers can work together to secure the sustainability of local news. Expected outcomes include a framewor ....Supporting the sustainability of Australia's local news ecosystem. This project aims to understand how Australia’s main public broadcaster, the ABC, can best support public interest journalism in rural and regional communities, with a specific focus on fragile and underserved areas of the nation’s local news ecosystem. The project will develop new knowledge around media power and how news providers can work together to secure the sustainability of local news. Expected outcomes include a framework to identify and define areas of news need, an assessment of existing interventions and road-tested approaches to improve information quality. The project should provide benefits by supporting forms of local journalism that ultimately enhances the demographic health and social fabric of small towns and cities.
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Amplifying Indigenous news: a digital intervention. This project aims to road-test, document and analyse an innovative strategy for amplifying Indigenous voices in news media. The project will deploy and assess the impact of a new digital application designed to enable access to a diverse range of Indigenous voices, stories and agendas. The anticipated outcomes will assist the project’s industry partners meet their strategic goals of increasing the level of Indigenous media representation in Aus ....Amplifying Indigenous news: a digital intervention. This project aims to road-test, document and analyse an innovative strategy for amplifying Indigenous voices in news media. The project will deploy and assess the impact of a new digital application designed to enable access to a diverse range of Indigenous voices, stories and agendas. The anticipated outcomes will assist the project’s industry partners meet their strategic goals of increasing the level of Indigenous media representation in Australia, and consolidate their roles as leading outlets for Indigenous content and coverage. These outcomes are also expected to improve public understanding of issues affecting Indigenous Australians and contribute to more informed and inclusive policy discussions.Read moreRead less
The importance of the fictional character in literary theory and cultural practice. This project is a theoretical research project which aims to make significant and innovative contributions to research excellence in literature and the history of ideas. This research focuses on the fictional character, one of the central categories of literary theory. The benefits flowing from it will primarily be an enhanced understanding of the workings and the history of a category that informs every domain o ....The importance of the fictional character in literary theory and cultural practice. This project is a theoretical research project which aims to make significant and innovative contributions to research excellence in literature and the history of ideas. This research focuses on the fictional character, one of the central categories of literary theory. The benefits flowing from it will primarily be an enhanced understanding of the workings and the history of a category that informs every domain of cultural practice.Read moreRead less