Development Of Statistical Methodologies And Application To Clinical Cancer Studies
Funder
National Health and Medical Research Council
Funding Amount
$428,065.00
Summary
Integrating different layers of information coming from the recent ‘-omics’ technologies can help improving the treatment and the prevention of complex diseases. In particular, the identification of molecular markers of different types can be used for better diagnostics and prognosis in cancer and immune diseases. This project will develop innovative statistical solutions to handle and make sense of the vast amount of biological data that are routinely generated in the laboratories.
Preventive messages and guidelines to reduce sitting — especially prolonged periods of sitting — have emerged. However, what prolonged sitting should be replaced with, and the feasibility of making real world changes to this behaviour, is unknown. This program of research will provide high quality evidence on the benefits of reducing prolonged sitting time, and the effectiveness and acceptability of achieving sitting reductions in real-world contexts.
Building Resilience To Support Healthy Families And Children
Funder
National Health and Medical Research Council
Funding Amount
$419,180.00
Summary
This research investigates effects of social adversity on the health of parents and carers and their children. We will examine the effects of adversity on parents’ and carers’ physical and mental health, health behaviours and capacity to provide care for their children, and how in turn children’s health and development may be affected. We will then examine whether designing health services that are responsive to families specific needs and strengths may help to promote health and resilience.
Genes, Biology And Environment In The Development Of Substance Use And Mental Health Disorders
Funder
National Health and Medical Research Council
Funding Amount
$475,910.00
Summary
Substance use and mental health disorders are major public health problems which cause long-term disabilities, poor health and early mortality. Addressing these problems requires a better understanding of the genetic, biological and environmental factors leading to these disorders. This research program represents a unique opportunity to increase our knowledge of the origins and mechanisms behind these disorders and significantly contribute to improved substance use and mental health prevention ....Substance use and mental health disorders are major public health problems which cause long-term disabilities, poor health and early mortality. Addressing these problems requires a better understanding of the genetic, biological and environmental factors leading to these disorders. This research program represents a unique opportunity to increase our knowledge of the origins and mechanisms behind these disorders and significantly contribute to improved substance use and mental health prevention policies and programs.Read moreRead less
Improving Community Approaches For Common Childhood Conditions.
Funder
National Health and Medical Research Council
Funding Amount
$478,602.00
Summary
Melissa’s end goal is community-based strategies that effectively prevent or manage common childhood conditions, which she addresses via four distinct yet unified programs of research (language-literacy, hearing loss, obesity, and early mental health-behaviour). All four programs are guided by long-term strategic plans that include advocacy and translation as central tenets. A further focus is research capacity-building in these areas via her substantial doctoral-postdoctoral programs.
Classifying Local Environmental Attributes For Healthier, More Equitable Child Development
Funder
National Health and Medical Research Council
Funding Amount
$437,034.00
Summary
Theory and evidence suggests rapid physical and social development makes children more sensitive to the impacts of environmental exposures than adults. Paradoxically, children’s environmental health is under-researched. My four-year vision is to support efforts to improve the health of children and to narrow child health inequities by co-producing new evidence that will help advocate for spatially targeted prevention initiatives and public policies in Australia.
Developing Better Models Of Outcome For Psychotic Disorders
Funder
National Health and Medical Research Council
Funding Amount
$458,695.00
Summary
Research on psychosis has been focused on developing treatments for hallucinations and delusions. However, ‘outcome’ is multifaceted and must embrace functioning, and quality of life. A/Prof Cotton will develop models will comprehensively capture ‘whole person’ outcomes for people who have experienced psychosis. Understanding how the disease impacts on the individual will enable better service planning, and refinement and development of treatments for patients with psychosis.
Improving Outcomes For Children With ADHD: Mapping Developmental Trajectories And Developing Targeted Interventions
Funder
National Health and Medical Research Council
Funding Amount
$419,180.00
Summary
Attention deficit hyperactivity disorder (ADHD) is one of the most common mental health disorders affecting young people in Australia. My research program aims to generate new knowledge to inform clinical practice for children with ADHD including: 1) long-term outcomes and key predictors of outcomes; and 2) novel treatments to improve the lives of children and families. Growth of my research program is feasible and underpinned by existing platforms including numerous NHMRC-funded studies.