Sodium homeostasis and the molecular basis for neurotoxin production by bacteria and algae. An understanding of the physiology of saxitoxin-producing microorgansims in response to salt stress is critical for the prevention of toxic blooms and for risk assessment of contaminated water bodies. This is nowhere more relevant than in the depleted and increasingly saline water resources of inland Australia. This project will develop genetic tests to assay for saxitoxin-producers and to monitor toxin p ....Sodium homeostasis and the molecular basis for neurotoxin production by bacteria and algae. An understanding of the physiology of saxitoxin-producing microorgansims in response to salt stress is critical for the prevention of toxic blooms and for risk assessment of contaminated water bodies. This is nowhere more relevant than in the depleted and increasingly saline water resources of inland Australia. This project will develop genetic tests to assay for saxitoxin-producers and to monitor toxin production in response to the environment, representing an easier, more economic and ethical alternative to current tests. The market for this type of predictive test includes environmental, anti-bioterrorism and fishery organisations. These genes will also allow the bioengineering of novel therapeutic drugs based on neuroactive alkaloids.Read moreRead less
Carbon costs of plant nutrient and water uptake. This project aims to investigate how much carbon plants need to invest belowground in return for water and nutrients. By using economic principles of supply and demand the project will quantify carbon expenditure for water and nutrients in grasslands and crops under different climate and land management scenarios. This project will use triple and quadruple isotope labelling techniques and explore the dependency of carbon investment on plant-microb ....Carbon costs of plant nutrient and water uptake. This project aims to investigate how much carbon plants need to invest belowground in return for water and nutrients. By using economic principles of supply and demand the project will quantify carbon expenditure for water and nutrients in grasslands and crops under different climate and land management scenarios. This project will use triple and quadruple isotope labelling techniques and explore the dependency of carbon investment on plant-microbial interactions and availability of belowground resources. Expected outcomes include new knowledge to build a universal framework about plant carbon-water-nutrient economics. This will benefit global carbon cycling models and efforts to increase nutrient and water use efficiencies in agricultural crops.Read moreRead less
Development and implementation of biodiversity information for sustainable management of South Australian groundwater. Clean potable water is one of the most important resources for human health and a successful economy. Increasingly, subterranean aquifers are used for storage and recovery of water. These aquifers contain dynamic ecosystems, but little is known about species composition or about the importance of the presence of various species for water quality. We will use the latest laborator ....Development and implementation of biodiversity information for sustainable management of South Australian groundwater. Clean potable water is one of the most important resources for human health and a successful economy. Increasingly, subterranean aquifers are used for storage and recovery of water. These aquifers contain dynamic ecosystems, but little is known about species composition or about the importance of the presence of various species for water quality. We will use the latest laboratory techniques and DNA identification methods to provide a template for determining ground water diversity and food web dynamics throughout Australia. This project will lead to a better understanding of how to manage ground water in a sustainable manner.Read moreRead less
The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments. The project will aim to collate data and map base-level distribution patterns of molecular and microbial markers of human sewage and natural/agricultural contamination with reference to diurnal and seasonal fluctuations. These data will then be used to develop decision support systems that predict contaminant dispersion and identify high-risk c ....The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments. The project will aim to collate data and map base-level distribution patterns of molecular and microbial markers of human sewage and natural/agricultural contamination with reference to diurnal and seasonal fluctuations. These data will then be used to develop decision support systems that predict contaminant dispersion and identify high-risk contamination sources. The diurnal collection of data is expected to show significant variations in the measured parameters associated with time of day, light intensity and temperature. Mapping of the sewage and nutrient loads throughout the year will provide base line data for identifying potential hotspots for targeting system upgrades or improved management programs.Read moreRead less
Managing acid mine drainage in northern Australia using microbial mats. One of the most difficult environmental issues for the mining industry is acid mine drainage (AMD) that can lead to significant environmental damage. This project aims to identify microbes and characterise their roles in AMD formation in north Australia. We will use our new knowledge to design and trial microbial mats for the treatment of AMD. A successful AMD microbial treatment technology will minimise the risk of acid run ....Managing acid mine drainage in northern Australia using microbial mats. One of the most difficult environmental issues for the mining industry is acid mine drainage (AMD) that can lead to significant environmental damage. This project aims to identify microbes and characterise their roles in AMD formation in north Australia. We will use our new knowledge to design and trial microbial mats for the treatment of AMD. A successful AMD microbial treatment technology will minimise the risk of acid runoff and metal seepage into rivers and through groundwater. AMD treatment technology we develop in the tropics where we experience the extremes of dry and wet seasons will require only minor modification to operate in temperate climates however the reverse is not true. Read moreRead less
Dynamic signaling pathways of dispersal in bacterial biofilms. This Breakthrough Science project will result in an increased understanding of the molecular processes that govern biofilm development and dispersal. While the outcomes will be directly applicable where P. aeruginosa infections continue to cause health-threatening conditions, such as in Cystic Fibrosis chronic infections, it will also be instrumental for the rational design of novel products and strategies to control biofilms of othe ....Dynamic signaling pathways of dispersal in bacterial biofilms. This Breakthrough Science project will result in an increased understanding of the molecular processes that govern biofilm development and dispersal. While the outcomes will be directly applicable where P. aeruginosa infections continue to cause health-threatening conditions, such as in Cystic Fibrosis chronic infections, it will also be instrumental for the rational design of novel products and strategies to control biofilms of other single species or of mixed species populations in many other settings. Countless environmental, industrial and clinical applications will benefit from improved antimicrobial strategies and reduced usage of antibiotics.Read moreRead less
Microbial community characterisation for bioprocessing of chlorinated hydrocarbon contaminated groundwater. Due to irresponsible industrial practices, Australia has hundreds of polluted soil and water environments. This includes the notorious groundwater contamination underlying Botany in Sydney, an area of rich industrial, residential and cultural significance. The use of microbes to clean up polluted environments, such as the Botany groundwater, is known as bioremediation - a process exploitin ....Microbial community characterisation for bioprocessing of chlorinated hydrocarbon contaminated groundwater. Due to irresponsible industrial practices, Australia has hundreds of polluted soil and water environments. This includes the notorious groundwater contamination underlying Botany in Sydney, an area of rich industrial, residential and cultural significance. The use of microbes to clean up polluted environments, such as the Botany groundwater, is known as bioremediation - a process exploiting the natural metabolic versatility of microbes. To clean up the polluted groundwater in Botany, mixed species communities of pollutant degrading microbes are being produced. Novel tools to reveal the inner workings of these microscopic communities are also being developed, giving Australia an unprecedented advantage in the global bioremediation market.Read moreRead less
Interactions between sulfur, nitrogen, and iron cycles in the sustainable management and use of acid sulfate soils. Acid Sulfate Soils (ASS) can cause major land management and environmental problems. It has been proposed that the linkages between the Sulfur, Nitrogen, and Iron biogeochemical cycles deterrmine the environmental and crop production hazards associated with use of ASS. In order to develop best management practices for ASS, it is important to research those linkages and determine th ....Interactions between sulfur, nitrogen, and iron cycles in the sustainable management and use of acid sulfate soils. Acid Sulfate Soils (ASS) can cause major land management and environmental problems. It has been proposed that the linkages between the Sulfur, Nitrogen, and Iron biogeochemical cycles deterrmine the environmental and crop production hazards associated with use of ASS. In order to develop best management practices for ASS, it is important to research those linkages and determine their contribution to fluxes of materials exported from these soils. This project will carry out that research and will transfer results to industry partners to improve land management practices and identify appropriate landuses in ASS landcapes.Read moreRead less
Development of the next generation of organo-mineral fertilisers utilising domestic and commercial waste products. Australian agriculture relies heavily on fertilisers and better products are needed that are derived from sustainable sources, have minimal adverse environmental impact and support high plant yields. This project will apply advanced approaches of nanostructural analysis and microbial ecology to developed next-generation organo-mineral fertilisers.
Colonisation by alien microbiota: identifying key ecological processes. This project aims to determine key ecological and molecular mechanisms that regulate microbial colonisation of new environments and their functional consequences. Microbial communities are important yet unseen contributors to the functioning of ecosystems, driving key ecological and economically important processes such as carbon and nutrient cycling. The project will provide a unifying framework for characterising colonisat ....Colonisation by alien microbiota: identifying key ecological processes. This project aims to determine key ecological and molecular mechanisms that regulate microbial colonisation of new environments and their functional consequences. Microbial communities are important yet unseen contributors to the functioning of ecosystems, driving key ecological and economically important processes such as carbon and nutrient cycling. The project will provide a unifying framework for characterising colonisation success of alien species across different scales, habitats, ecosystem types and environmental disturbance such as climate change.Read moreRead less