Atherosclerosis - The Key Roles Of HDL, Cell Cholesterol Metabolism And Vascular Function
Funder
National Health and Medical Research Council
Funding Amount
$7,085,050.00
Summary
Atherosclerosis, an accumulation of cholesterol in the artery wall, is a major cause of illness and premature death worldwide. It is caused by conditions such as low levels of the protective high density lipoproteins (HDLs), diabetes, smoking and abnormal function of arteries, all of which are linked to disorders of cholesterol metabolism. With our expertise in HDLs, cholesterol metabolism and artery function, our research will lead to the development of novel strategies for early detection and ....Atherosclerosis, an accumulation of cholesterol in the artery wall, is a major cause of illness and premature death worldwide. It is caused by conditions such as low levels of the protective high density lipoproteins (HDLs), diabetes, smoking and abnormal function of arteries, all of which are linked to disorders of cholesterol metabolism. With our expertise in HDLs, cholesterol metabolism and artery function, our research will lead to the development of novel strategies for early detection and prevention of atherosclerosis and heart disease.Read moreRead less
Linking Lifestyle And Molecular Biology To Inform Precision Public Health For Major Cancers
Funder
National Health and Medical Research Council
Funding Amount
$8,487,111.00
Summary
The Program of research seeks to increase our understanding of cancer risk. We will use our large collections of population and family-based datasets to conduct innovative analyses, improving our understanding of the roles that genetic, epigenetic and lifestyle factors play in our risk of breast, colorectal and prostate cancer. This information should allow us to better predict a person’s cancer risk, enabling public health interventions, such as screening, to be delivered more effectively and e ....The Program of research seeks to increase our understanding of cancer risk. We will use our large collections of population and family-based datasets to conduct innovative analyses, improving our understanding of the roles that genetic, epigenetic and lifestyle factors play in our risk of breast, colorectal and prostate cancer. This information should allow us to better predict a person’s cancer risk, enabling public health interventions, such as screening, to be delivered more effectively and economically to those most at risk.Read moreRead less