Development of a novel biodegradable ophthalmic biomaterial based on porous silicon. Within this interdisciplinary project, we will combine our diverse expertise towards the development of frontier technologies for control of stem cell behaviour on biodegradable scaffold materials. We will develop a novel ophthalmic bioimplant from porous silicon using topographical and chemical aspects of surface modification as well as immobilisation and/or incorporation of bioactive species such as growth fac ....Development of a novel biodegradable ophthalmic biomaterial based on porous silicon. Within this interdisciplinary project, we will combine our diverse expertise towards the development of frontier technologies for control of stem cell behaviour on biodegradable scaffold materials. We will develop a novel ophthalmic bioimplant from porous silicon using topographical and chemical aspects of surface modification as well as immobilisation and/or incorporation of bioactive species such as growth factors, to permit the growth and differentiation of mammalian stem cells. This project will result in biomaterials for the treatment of blinding diseases of the eye. Implanted into the limbus, bioimplants may ameliorate some common corneal diseases.Read moreRead less
Control Of Aggregate Structure, Settling And Dewatering In Mineral Tailings Processing. Modification of aggregate structures in mineral processing will lead to improved dewatering in tailings operations. In mine site rehabilitation and tailings utilisation, technology developed in this project may save not only millions of dollars in more efficient processing and tailing deposition but also help to better reuse our limited national water resources.
Model Studies of the Wettability of Reservoir and Seal Rocks as Recovered and After Treatments to Alter Surface Properties. Key contributions will be made to the science that underpins petroleum recovery. The combination of diverse expertise in interfacial physics and chemistry, petroleum geology and petrophysics provides a large innovative potential for the industry. Two graduate students will be educated in a rich multi-disciplinary research environment with a strong emphasis on both academic ....Model Studies of the Wettability of Reservoir and Seal Rocks as Recovered and After Treatments to Alter Surface Properties. Key contributions will be made to the science that underpins petroleum recovery. The combination of diverse expertise in interfacial physics and chemistry, petroleum geology and petrophysics provides a large innovative potential for the industry. Two graduate students will be educated in a rich multi-disciplinary research environment with a strong emphasis on both academic and industrial aspects of the problems. The research conducted will enable the industrial partners to improve existing technologies for predicting where oil and gas is trapped and for petroleum recovery.
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Optimisation of Coal Flotation Performance. The aim of this project is to improve the cleaning of coal by flotation across the whole particle size range with maximum rejection of mineral matter and decreased reagent consumption. The factors that influence coal flotation will be identified and used to predict coal flotation performance. In particular the ultimate separability of coal will be addressed through a unique combination of in- and ex- situ pulp chemical and physical measurements, embedd ....Optimisation of Coal Flotation Performance. The aim of this project is to improve the cleaning of coal by flotation across the whole particle size range with maximum rejection of mineral matter and decreased reagent consumption. The factors that influence coal flotation will be identified and used to predict coal flotation performance. In particular the ultimate separability of coal will be addressed through a unique combination of in- and ex- situ pulp chemical and physical measurements, embedded in a comprehensive model of coal flotation.Read moreRead less
Multifunctional mixed matrix membranes incorporating aligned carbon nanotubes. The pressure on water supplies in Australia will only increase in coming years meaning that effective and cheap means of recycling water must be found. By developing a carbon nanotube-based water filtration system, we intend to promote the growth of Australia's world-class reputation in water remediation. The technological outcomes from this research will lead to direct economic and environmental benefits for the comm ....Multifunctional mixed matrix membranes incorporating aligned carbon nanotubes. The pressure on water supplies in Australia will only increase in coming years meaning that effective and cheap means of recycling water must be found. By developing a carbon nanotube-based water filtration system, we intend to promote the growth of Australia's world-class reputation in water remediation. The technological outcomes from this research will lead to direct economic and environmental benefits for the community and offer commercial opportunities for industry. Training research scientists of the future forms an integral part of our program as it is crucial to maintain a critical mass in this potentially forthcoming water based economy.
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Towards a Molecular-Scale Understanding of Sorption of Organic Pollutants to Soil. The toxicity, mobility and persistence of organic pollutants in soils are in large part controlled by their sorption to soil organic matter. The chemical nature or quality of the organic matter affects not only the amount of chemical sorbed, but also the reversibility of sorption and the rate of sorption and desorption. Until now, only bulk measures of soil organic matter chemistry have been considered in sorption ....Towards a Molecular-Scale Understanding of Sorption of Organic Pollutants to Soil. The toxicity, mobility and persistence of organic pollutants in soils are in large part controlled by their sorption to soil organic matter. The chemical nature or quality of the organic matter affects not only the amount of chemical sorbed, but also the reversibility of sorption and the rate of sorption and desorption. Until now, only bulk measures of soil organic matter chemistry have been considered in sorption studies. This project introduces novel spectroscopic techniques that for the first time identify the chemical environment of sorbed molecules at the molecular scale. This will enable better prediction of pollutant transport and degradation.Read moreRead less
Enhancing Seagrass Restoration : Improving Hessian Durability in Marine Environments. The establishment of an environmentally benign method for restoration of seagrass beds (which provide habitat for a wide range of commercially, recreationally and ecologically important marine species) will enhance Australia's capability of maintaining its coastal marine environment in support of its fishing and ecotourism industries. Furthermore, it will ultimately improve our capacity to manage the environmen ....Enhancing Seagrass Restoration : Improving Hessian Durability in Marine Environments. The establishment of an environmentally benign method for restoration of seagrass beds (which provide habitat for a wide range of commercially, recreationally and ecologically important marine species) will enhance Australia's capability of maintaining its coastal marine environment in support of its fishing and ecotourism industries. Furthermore, it will ultimately improve our capacity to manage the environmental impact of human development on our natural resources. If successful, the knowledge gained of the dynamics of marine biofilms on differentially coated natural fibers could facilitate broader application of methods used in environmental restoration and marine based industries, and foreshadow new applications.Read moreRead less
Impact of recycled and low quality process water on sustainable mineral processing practices. Water is in short supply and needs to be considered as a 'key reagent'. The quality of this reagent can vary widely. For a sustainable mineral processing practice, the use of recycled or low quality/saline process water will be essential for a plant to operate in the future. The major benefit is recognition that significant recycle of process water for flotation is achievable if simple water quality con ....Impact of recycled and low quality process water on sustainable mineral processing practices. Water is in short supply and needs to be considered as a 'key reagent'. The quality of this reagent can vary widely. For a sustainable mineral processing practice, the use of recycled or low quality/saline process water will be essential for a plant to operate in the future. The major benefit is recognition that significant recycle of process water for flotation is achievable if simple water quality control and management practices are implemented. In addition, a better understanding and control of water quality in recycled/saline process water may lead to improved flotation stability and performance, and reduced reagent consumption.Read moreRead less
NEUTRALISING MINERAL REACTIONS IN ACID MINE DRAINAGE CONTROL. The project addresses the serious environmental problem of acid and toxic element release from iron sulfides in waste rock dumps and tailings storage in the mining industry. Long-term neutralising capacity, currently not tested in laboratory assessments, is available from the reaction of some silicate and aluminosilicate minerals. This potential has not been systematically tested or modelled. The research project aims to understand th ....NEUTRALISING MINERAL REACTIONS IN ACID MINE DRAINAGE CONTROL. The project addresses the serious environmental problem of acid and toxic element release from iron sulfides in waste rock dumps and tailings storage in the mining industry. Long-term neutralising capacity, currently not tested in laboratory assessments, is available from the reaction of some silicate and aluminosilicate minerals. This potential has not been systematically tested or modelled. The research project aims to understand the relative mechanisms and rates for long-term alleviation of acid production with mineral layered and blended combinations. Improved understanding will provide methodology for assessment and control of acid mine drainage.Read moreRead less
Physico-chemical and Biopharmaceutical Investigations of Novel Drug Delivery Systems for Oral Administration of Lipophilic Drugs. The new platform technology for carrying lipophilic molecules will be applicable to many molecules currently under development by Australian Industry and will inspire novel encapsulation approaches to new and existing drugs as well as functional foods and nutraceuticals. Improved oral bioavailability of anticancer drugs will improve the quality of life of patients, re ....Physico-chemical and Biopharmaceutical Investigations of Novel Drug Delivery Systems for Oral Administration of Lipophilic Drugs. The new platform technology for carrying lipophilic molecules will be applicable to many molecules currently under development by Australian Industry and will inspire novel encapsulation approaches to new and existing drugs as well as functional foods and nutraceuticals. Improved oral bioavailability of anticancer drugs will improve the quality of life of patients, reduce health care costs and provide broader benefits to the community. The Australian biotechnology/pharmaceutical industries can share in a greater proportion of the US$50 billion market for specialised drug delivery, which is increasing by 20% annually. Australia's scientific competitiveness will be strengthened in the fields of nano-encapsulation and colloidal delivery.Read moreRead less