A Randomised Controlled Trial Of Interventional Versus Conservative Treatment Of Primary Spontaneous Pneumothorax
Funder
National Health and Medical Research Council
Funding Amount
$412,315.00
Summary
Primary spontaneous pneumothorax (PSP) is a collapsed lung that occurs in otherwise healthy people without underlying lung disease. Current standard treatment is to insert a chest drain into the chest to remove the air around the collapsed lung so that the lung re-inflates rapidly ("interventional treatment"). We will determine whether doing nothing, i.e. letting the lung re-inflate slowly on its own over several weeks ("conservative treatment"), is just as good or even better for patients.
Group A Streptococcal Human Challenge Study: Accelerating Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$2,018,741.00
Summary
Infection with group A streptococcus (GAS) is a major cause of morbidity and mortality worldwide, including in the Aboriginal population of Australia. Concerted efforts for vaccine development have been hampered by the absence of a suitable animal model. To address this critical knowledge gap we propose to develop a controlled human infection model of GAS infection. This model will provide a direct pathway for the future appraisal of novel GAS vaccines.
Developmental Schizotypy In The General Population: Early Risk Factors And Predictive Utility.
Funder
National Health and Medical Research Council
Funding Amount
$830,952.00
Summary
This study will determine early childhood risk factors for psychosis-proneness in children aged 11 years, and emerging signs and symptoms of mental health disorders of these children, using population data from the NSW Child Development Study. Determining risk for psychosis as early as possible in the life course will enable the provision of preventative interventions to children at critical points in development.
Seeding Success: Identifying Factors That Contribute To Positive Early Childhood Health And Development In Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$692,845.00
Summary
This study will identify the key drivers of positive early childhood health and development in Aboriginal children, and the features of local communities and early childhood service provision that make a tangible difference, using a large population-based cohort of children in NSW. We will apply novel methods for using linked population data that can be used to inform program planning and evaluation nationally, and will advance theory, research and practice to "seed success" for Aboriginal child ....This study will identify the key drivers of positive early childhood health and development in Aboriginal children, and the features of local communities and early childhood service provision that make a tangible difference, using a large population-based cohort of children in NSW. We will apply novel methods for using linked population data that can be used to inform program planning and evaluation nationally, and will advance theory, research and practice to "seed success" for Aboriginal children.Read moreRead less