Pathogenesis Of Persistent Human Virus Infections Of Global Significance
Funder
National Health and Medical Research Council
Funding Amount
$6,571,328.00
Summary
The study will investigate why humans cannot eradicate particular viruses (HIV-AIDS, cytomegalovirus and herpes simplex virus), the long term effects of these viruses and ways to improve control. Current treatments can only partly suppress the levels of these viruses, because they persist in certain parts of the body called reservoirs, only to resurge later causing disease. Thus, the overall aim of the research program is to discover the mechanisms by which these viruses are able to successfully ....The study will investigate why humans cannot eradicate particular viruses (HIV-AIDS, cytomegalovirus and herpes simplex virus), the long term effects of these viruses and ways to improve control. Current treatments can only partly suppress the levels of these viruses, because they persist in certain parts of the body called reservoirs, only to resurge later causing disease. Thus, the overall aim of the research program is to discover the mechanisms by which these viruses are able to successfully persist within reservoirs in the human body. The research program brings together a group of 6 leading scientists and clinicians located at 3 sites in 2 Australian cities. The team is comprised of experts in the study of HIV-AIDS, cytomegalovirus and herpes simplex virus who will combine their knowledge and expertise to speed up the process of research on these viruses that are of major health importance. Studies will also utilise a number of cutting edge technologies that now make it possible to much more rapidly and precisely determine how viruses cause disease. Advances in our understanding of how viruses persist may form the basis for treatments aimed at controlling persistent infections and the serious diseases caused by these viruses.Read moreRead less
Islamic religiosity and challenge of political engagement and national belonging in multicultural western cities. This project will investigate how participation in Islamic religious practices strengthens attachments to the western cities where Muslims have chosen to live. It will contribute to global, national and local policy outcomes that focus on the challenges of accommodating minority religions in diverse western cities.
Comparing immigration policy in the group of five: developing an evidence base for evaluating the role of policy in international migration. Testing the impact of immigration policy is an interdisciplinary, multi-national study evaluating the policy management of immigration movements over 50 years and across the five countries Australia uses as comparators. It includes a detailed study of measures to deter and otherwise control irregular migration.
Settlement outcomes of Syrian-conflict refugee families in Australia. This project aims to focus on the policy responses to, and settlement outcomes for, Syrian-conflict refugee families in Australia with an emphasis on employment and education. The Syrian conflict has generated an unprecedented flow of refugees across Europe and other countries, including Australia. These countries face new challenges in providing successful settlement outcomes for the refugees. Utilising a longitudinal study o ....Settlement outcomes of Syrian-conflict refugee families in Australia. This project aims to focus on the policy responses to, and settlement outcomes for, Syrian-conflict refugee families in Australia with an emphasis on employment and education. The Syrian conflict has generated an unprecedented flow of refugees across Europe and other countries, including Australia. These countries face new challenges in providing successful settlement outcomes for the refugees. Utilising a longitudinal study of 250 refugee families and fieldwork in key areas of high refugee settlement in NSW, Victoria and Queensland, this project will generate comparative insights to identify policy and program responses that lead to the most successful settlement outcomes. Improved employment, education and settlement outcomes for refugees will have economic, social and cultural benefits for Australian society and improve the quality of life of refugees.Read moreRead less