Discovering the First Generation of Stars in the Galaxy - The Most Metal-Poor Stars. The most metal-poor stars carry a fossil record of the early chemical and dynamical evolution of the Galaxy. The most interesting objects are those with the lowest metal abundances representing the earliest generation of stars in the Galaxy. The aim of the present project is to extend the mining of the HES objective spectra to identify extremely metal-deficient giants, which together with the already identified ....Discovering the First Generation of Stars in the Galaxy - The Most Metal-Poor Stars. The most metal-poor stars carry a fossil record of the early chemical and dynamical evolution of the Galaxy. The most interesting objects are those with the lowest metal abundances representing the earliest generation of stars in the Galaxy. The aim of the present project is to extend the mining of the HES objective spectra to identify extremely metal-deficient giants, which together with the already identified dwarfs will be further distilled using 6dF and the DBS. We anticipate trebling the total number of the most metal deficient stars known and targeting these for observations with 8m telescopes.Read moreRead less
What are the determinants and effects of school choice? An international comparison between Australia and the UK. The project will provide a clearer picture of the determinants of school choice, most notably the impact of economic phenomena on that choice. For Australia, this will mean we have a better understanding of the competing explanations of the growth of students at private schools over the past three decades: the role of government subsidies; the role of demographic changes; the effec ....What are the determinants and effects of school choice? An international comparison between Australia and the UK. The project will provide a clearer picture of the determinants of school choice, most notably the impact of economic phenomena on that choice. For Australia, this will mean we have a better understanding of the competing explanations of the growth of students at private schools over the past three decades: the role of government subsidies; the role of demographic changes; the effects of increased income inequality; and the role of changes in preferences towards private schools. This information will provide a better evidence base for future policy development in this area.Read moreRead less
Positron processes - From Basic to Applied Science. Australian scientists are at the forefront of international activities in atomic and molecular physics and materials science research. This program will expand the level of expertise in an emerging field that has importance in both these areas - the use of positron beams. Australia is developing a new and exciting capacity for positron research through the National Positron Beamline Facility. Scientists in this collaboration will work with o ....Positron processes - From Basic to Applied Science. Australian scientists are at the forefront of international activities in atomic and molecular physics and materials science research. This program will expand the level of expertise in an emerging field that has importance in both these areas - the use of positron beams. Australia is developing a new and exciting capacity for positron research through the National Positron Beamline Facility. Scientists in this collaboration will work with other outstanding, international research groups in the field of positron studies to stimulate new directions for their research. The international links, and the novel capabilities of the new Australian Facility, will enable our researchers to fully exploit this new field of research.Read moreRead less
The differential impact of performance-based and size-based funding of university research in Australia and Germany. The project will significantly increase knowledge about organisational and individual responses to systems of financing university research. A comparison of University research in Australia to a 'ground state' of research that has not been affected by evaluation-based funding will assist Australian policy makers to better manage the use of tax payer dollars to fund research. The ....The differential impact of performance-based and size-based funding of university research in Australia and Germany. The project will significantly increase knowledge about organisational and individual responses to systems of financing university research. A comparison of University research in Australia to a 'ground state' of research that has not been affected by evaluation-based funding will assist Australian policy makers to better manage the use of tax payer dollars to fund research. The project will identify adaptive behaviour, and will thus support the discussion about possible consequences of the upcoming new Research Quality Framework in Australia. German science policy will benefit from insights into the long-term effects of formula-based funding that cannot as yet be observed in Germany.Read moreRead less
Single Molecule Studies of Replisomal Function. It has recently become possible to watch the copying of DNA molecules with a specialized microscope in real time. This process requires assembly of a complex molecular machine on the DNA, followed by triggering of its function, and yields exquisitely detailed information about how the machine works. In this new collaboration between scientists in Australia and the U.S.A., we will assemble these machines on single DNA molecules, watch how they work ....Single Molecule Studies of Replisomal Function. It has recently become possible to watch the copying of DNA molecules with a specialized microscope in real time. This process requires assembly of a complex molecular machine on the DNA, followed by triggering of its function, and yields exquisitely detailed information about how the machine works. In this new collaboration between scientists in Australia and the U.S.A., we will assemble these machines on single DNA molecules, watch how they work and simultaneously measure the very small forces that the machines generate. This will give Australian scientists access to a new technology for studying molecular machines.Read moreRead less
Identification of structural proteins in the tissue cyst wall of Toxoplasma gondii. Most infections with Toxoplasma gondii are asymptomatic, however, infection during pregnancy can lead to miscarriage or blindness, deafness and mental retardation in the developing baby. Furthermore, in AIDS patients, toxoplasmosis is the leading cause of fatal encephalitis as the normally dormant tissue cysts are reactivated in the absence of an effective immune system. In Australia, it has been estimated that ~ ....Identification of structural proteins in the tissue cyst wall of Toxoplasma gondii. Most infections with Toxoplasma gondii are asymptomatic, however, infection during pregnancy can lead to miscarriage or blindness, deafness and mental retardation in the developing baby. Furthermore, in AIDS patients, toxoplasmosis is the leading cause of fatal encephalitis as the normally dormant tissue cysts are reactivated in the absence of an effective immune system. In Australia, it has been estimated that ~30% of the population is infected with T. gondii and the occurrence of congenital toxoplasmosis is 0.2% of live births, which translates to roughly 500 cases/year. Our research will identify structural proteins in Toxoplasma cyst walls that will lead to the design of new strategies to control the diseases caused by these parasites.Read moreRead less