Resilience and coping: Predicting positive well-being following life transitions and major life events among young Australian women. The project addresses a major issue for the well-being of Australians. It examines positive well-being and resilience, which provides an important complement to other work on diagnosed mental illness. Mental health problems are a major problem in Australia, contributing to unemployment, family problems, and risky life choices. By identifying people who maintain goo ....Resilience and coping: Predicting positive well-being following life transitions and major life events among young Australian women. The project addresses a major issue for the well-being of Australians. It examines positive well-being and resilience, which provides an important complement to other work on diagnosed mental illness. Mental health problems are a major problem in Australia, contributing to unemployment, family problems, and risky life choices. By identifying people who maintain good psychological health despite life stress, it can help in prevention and early intervention. It focuses on the important years of early adulthood, when people are dealing with new relationships, employment, and family formation. Its focus on women reflects the fact that women and men experience different life courses, often diverging markedly when the first child arrives.Read moreRead less
Beyond psychopathology: Pathways to suicide in mentally well young adult males. Increased knowledge of risk factors for suicide among mentally well males can lead to better informed preventive health policies, earlier intervention and community education. The tragic impacts of suicide lead to long-term societal problems which result in disconnection and alienation, particularly for those who are left behind; findings from this study will assist development of initiatives aimed at increasing soci ....Beyond psychopathology: Pathways to suicide in mentally well young adult males. Increased knowledge of risk factors for suicide among mentally well males can lead to better informed preventive health policies, earlier intervention and community education. The tragic impacts of suicide lead to long-term societal problems which result in disconnection and alienation, particularly for those who are left behind; findings from this study will assist development of initiatives aimed at increasing social connectedness and awareness. Also, males compose the predominant workforce in Australia and the costs saved as a result of effective prevention initiatives may be enormous, given that economic costs to suicide are estimated at 900 million dollars annually. Read moreRead less
Rethinking women's depression through narratives of recovery and wellbeing. This research project explores the growing problem of depression for women in Australia from a new angle. It investigates how rural and urban women at different life stages talk about their own experiences of recovery from depression and what helped to improve their emotional wellbeing. By considering the social and gendered context of women's depression this project will contribute to a broader evidence base for preven ....Rethinking women's depression through narratives of recovery and wellbeing. This research project explores the growing problem of depression for women in Australia from a new angle. It investigates how rural and urban women at different life stages talk about their own experiences of recovery from depression and what helped to improve their emotional wellbeing. By considering the social and gendered context of women's depression this project will contribute to a broader evidence base for prevention policies and treatment practices. It will also enable different ways of approaching women's depression amongst health professionals, families and communities.Read moreRead less
Epigenetic mechanisms regulating sex differences in fear-related learning and memory. Anxiety disorders represent an enormous burden on society and are associated with premature aging and infertility in men and women. Evidence also indicates that parental anxiety affects child development. Given that fear-related learning has an important influence on emotional health which, in turn, affects lifestyle and the aging process, an understanding of the neural mechanisms mediating sex differences in ....Epigenetic mechanisms regulating sex differences in fear-related learning and memory. Anxiety disorders represent an enormous burden on society and are associated with premature aging and infertility in men and women. Evidence also indicates that parental anxiety affects child development. Given that fear-related learning has an important influence on emotional health which, in turn, affects lifestyle and the aging process, an understanding of the neural mechanisms mediating sex differences in fear learning will enhance our ability to develop better therapeutic approaches for treating anxiety and preventing relapse, potentially through a gender-specific approach. The studies outlined in this proposal will have implications for promoting and maintaining good health.Read moreRead less
Young Carers: Investigation of the Psychosocial Impact of Caregiving on Youth Who Have a Parent with an Illness or Disability. This project addresses a growing national public health concern; the welfare of youth affected by parental illness/disability. There is a projected increase in reliance on unpaid care, and young carers are an important but hidden and neglected carer group. Although young carers have recently emerged on the political agenda, the research in this field is at an early descr ....Young Carers: Investigation of the Psychosocial Impact of Caregiving on Youth Who Have a Parent with an Illness or Disability. This project addresses a growing national public health concern; the welfare of youth affected by parental illness/disability. There is a projected increase in reliance on unpaid care, and young carers are an important but hidden and neglected carer group. Although young carers have recently emerged on the political agenda, the research in this field is at an early descriptive stage resulting in a lack of empirical data to inform policy and service development. There is a critical need for data that elucidates young caregiving in Australia. This project will establish new methodologies and frameworks and provide data that will inform policy and services that promote the healthy development of youth affected by parental illness/disability.Read moreRead less
Popping the Bubblewrap, Unleashing the Power of Play. The long-term costs of childhood obesity, bullying and poor mental health are staggering. Despite the investment of billions of dollars for prevention and intervention, the statistics continue to worsen. We offer a simple, sustainable, cost-effective programme of prevention aimed at important national priorities within health and research. We expect to demonstrate a significant effect on children's activity levels, coping and social skills th ....Popping the Bubblewrap, Unleashing the Power of Play. The long-term costs of childhood obesity, bullying and poor mental health are staggering. Despite the investment of billions of dollars for prevention and intervention, the statistics continue to worsen. We offer a simple, sustainable, cost-effective programme of prevention aimed at important national priorities within health and research. We expect to demonstrate a significant effect on children's activity levels, coping and social skills through strategies that are replicable in every school playground in the nation and to contribute to policy regarding play, health, and education.Read moreRead less
The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The curr ....The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The current project is directly relevant to the genetics of mental disorders, such as attention deficit hyperactivity (ADHD), that place a large burden, both financially and emotionally, on our society. Understanding the genes and biological pathways that increase risk for mental disorders will ultimately lead to improved treatments for these conditions.Read moreRead less
Assessing gene function in the developing brain using zebrafish as a model system. As the average life expectancy in western countries increases there is an increasing incidence of mental health problems in the general population. Therapeutic approaches to Alzhemier's and Parkinson's disease as well as to brain injury arising from stroke rely on a thorough understanding of the molecular and physiological mechanisms of normal growth of this tissue. These are the very processes that need to be rea ....Assessing gene function in the developing brain using zebrafish as a model system. As the average life expectancy in western countries increases there is an increasing incidence of mental health problems in the general population. Therapeutic approaches to Alzhemier's and Parkinson's disease as well as to brain injury arising from stroke rely on a thorough understanding of the molecular and physiological mechanisms of normal growth of this tissue. These are the very processes that need to be reactivated in these diseases for recovery of function. This project seeks to understand normal development of the brain and in doing so it will expose novel targets for therapy in the aged. Read moreRead less
Understanding the mechanisms of GABA type-A receptor activation and drug modulation. There is currently little understanding of how sedative and anxiolytic drugs, including valium, interact with their receptors in the brain. This project will dramatically increase our understanding of how these receptors work and how drugs affect their activity. This will provide new insights into drug discovery and design.
Thwarted Identity: The Missing Link Between Psychopathology and Prejudice. Prejudice and the extremist violence that arises from it are typically explained either by the psychopathology of individual perpetrators, or by their membership of extremist groups. This project will seek to reconcile these competing explanations and resolve this impasse that has obstructed progress in combating prejudice. This project develops a new framework specifying causal and reciprocal links between the novel conc ....Thwarted Identity: The Missing Link Between Psychopathology and Prejudice. Prejudice and the extremist violence that arises from it are typically explained either by the psychopathology of individual perpetrators, or by their membership of extremist groups. This project will seek to reconcile these competing explanations and resolve this impasse that has obstructed progress in combating prejudice. This project develops a new framework specifying causal and reciprocal links between the novel concept of thwarted identity, psychopathology, ideology, and prejudice. Expected outcomes are new policy solutions and novel targets for interventions to reduce prejudice and extremist violence, which will deliver significant benefit by addressing these pernicious social problems.Read moreRead less