Paving the way for effective public health interventions for bulimic eating disorders: Understanding stigma and mental health literacy. This research contributes to promoting and maintaining good health. The burden of bulimic eating disorders in the community is high, frequently ignored and increasing. Our research will pave the way for improved understanding of eating disorders and a reduction of stigma in relation to these problems. In so doing, it will lead to reduced shame and suffering for ....Paving the way for effective public health interventions for bulimic eating disorders: Understanding stigma and mental health literacy. This research contributes to promoting and maintaining good health. The burden of bulimic eating disorders in the community is high, frequently ignored and increasing. Our research will pave the way for improved understanding of eating disorders and a reduction of stigma in relation to these problems. In so doing, it will lead to reduced shame and suffering for people with eating disorders and enhance appropriate treatment seeking and the quality of advice received from family, friends and health professionals. A public health intervention based on our findings will contribute to a more tolerant and understanding community.Read moreRead less
Cognitive neuroscience of spatial asymmetry: behaviour, genes and brain imaging. When humans distribute their attention in space, biases or asymmetries of spatial attention exist. Healthy individuals exhibit a processing advantage favouring left space but this advantage is lost in disorders such as unilateral spatial neglect, ADHD and dyslexia. This project will develop novel electrophysiological methods to dissociate the sensory, attentional, decision-making and motoric contributions to spatial ....Cognitive neuroscience of spatial asymmetry: behaviour, genes and brain imaging. When humans distribute their attention in space, biases or asymmetries of spatial attention exist. Healthy individuals exhibit a processing advantage favouring left space but this advantage is lost in disorders such as unilateral spatial neglect, ADHD and dyslexia. This project will develop novel electrophysiological methods to dissociate the sensory, attentional, decision-making and motoric contributions to spatial asymmetries. By interfacing electrophysiology with genetic, neurochemical and brain imaging methods, this project will comprehensively map the biology of spatial asymmetry. This knowledge is vital to developing effective treatments for disorders where atypical patterns of spatial asymmetry index neurological vulnerability.Read moreRead less
Social outcomes, behaviour and emotional well-being of adults with autism. It is recognised that autism results in substantial life-long disability. Severe emotional and behavioural problems are likely to be a key factor in precluding adults with autism from work, independent living, social contact, and undermine their quality of life, thus increasing support needs. This project aims to address a major gap in our current knowledge - the association between severe emotional and behavioural proble ....Social outcomes, behaviour and emotional well-being of adults with autism. It is recognised that autism results in substantial life-long disability. Severe emotional and behavioural problems are likely to be a key factor in precluding adults with autism from work, independent living, social contact, and undermine their quality of life, thus increasing support needs. This project aims to address a major gap in our current knowledge - the association between severe emotional and behavioural problems in adults with autism and social outcomes. Identification of markers of adult outcomes aims to lead to an improved understanding of the pathways to better social outcomes, facilitating the development of specific interventions to provide much needed improvements in outcomes for adults with autism.Read moreRead less
The effect of cochlear implants on cognitive decline in ageing Australians. This project aims to investigate the impact of cochlear implants on cognitive function in elderly people with deafness. Deafness has been found to be independently associated with a 30–40 per cent accelerated rate of cognitive decline in elderly adults. There is currently no effective treatment for cognitive decline. The intended outcomes of this observational study will help us to understand the biological process of co ....The effect of cochlear implants on cognitive decline in ageing Australians. This project aims to investigate the impact of cochlear implants on cognitive function in elderly people with deafness. Deafness has been found to be independently associated with a 30–40 per cent accelerated rate of cognitive decline in elderly adults. There is currently no effective treatment for cognitive decline. The intended outcomes of this observational study will help us to understand the biological process of cognitive decline, whether hearing loss is causal, and whether the process can be altered. These findings should be applicable to all individuals with hearing loss. If cochlear implants delay cognitive decline, this would significantly affect policy, quality of life for the elderly, and the cost to society.Read moreRead less
The Power of Causal Attributions: Genetic Essentialist Biases and Health. Great advancements in the science of genetics are accompanied by increased public propensity to attribute causality to the genes for diverse outcomes such as abilities, social group differences, attitudes, and diseases. These genetic attributions activate cognitive biases termed Genetic Essentialist Biases, which have been shown to instigate a variety of deleterious outcomes. The project will evaluate hypothesized detrimen ....The Power of Causal Attributions: Genetic Essentialist Biases and Health. Great advancements in the science of genetics are accompanied by increased public propensity to attribute causality to the genes for diverse outcomes such as abilities, social group differences, attitudes, and diseases. These genetic attributions activate cognitive biases termed Genetic Essentialist Biases, which have been shown to instigate a variety of deleterious outcomes. The project will evaluate hypothesized detrimental effects of genetic attributions on actual health behaviours, endorsement of health policies, and disease related stigma. Furthermore, it will test interventions designed to reduce the negative effects of such attributions on attitudes, beliefs, intentions, and behaviours related to a common disease. Read moreRead less
Cannabis and the brain: the good, the bad and the unknown. Cannabis is the most widely used illicit drug but much remains unknown about how it affects the brain. This research will examine effects on brain cells through to whole brain function in humans to determine how cannabis use may lead to impaired thinking or psychological symptoms and why cannabis might affect individuals in different ways.
Investigating the role of Zona Incerta RXFP3+ cells in learning and memory. Learning and memory are fundamental to human and animal behaviour. We identified a specific population of cells in the zona incerta of the brain, where activation inhibits expression of memory, and facilitates the acquisition of new learning. Aside from our observations, nothing is currently known about the anatomy and function of these cells. This project aims to map how they connect to the rest of the brain, to observe ....Investigating the role of Zona Incerta RXFP3+ cells in learning and memory. Learning and memory are fundamental to human and animal behaviour. We identified a specific population of cells in the zona incerta of the brain, where activation inhibits expression of memory, and facilitates the acquisition of new learning. Aside from our observations, nothing is currently known about the anatomy and function of these cells. This project aims to map how they connect to the rest of the brain, to observe how these connections are recruited during learning and memory, and then to test their function experimentally. The outcomes will extend the known neural circuitry that controls learning by defining how and where these unexplored pathways fit within it; thus advancing knowledge regarding neural regulation of behaviour.
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Hunger flexibly modifies hypothalamic neural circuits responding to threat. Animal and human behaviour frequently involves a choice between actions or goals with conflicting positive and negative outcomes. However, the appropriate action or goal in conflicting situations often depends on physiological pressures like hunger, stress and mating opportunities. For example, the need for resources within an environment, such as food, drives approach behaviour, whereas threats to survival, such as pred ....Hunger flexibly modifies hypothalamic neural circuits responding to threat. Animal and human behaviour frequently involves a choice between actions or goals with conflicting positive and negative outcomes. However, the appropriate action or goal in conflicting situations often depends on physiological pressures like hunger, stress and mating opportunities. For example, the need for resources within an environment, such as food, drives approach behaviour, whereas threats to survival, such as predator cues, enhance avoidance behaviour. This project will uncover the neural circuitry and endocrine mechanisms through which hunger influences hypothalamic threat-detecting circuits that suppress food intake. These studies provide a new hypothalamic model to understand risk/reward decision in the brain.Read moreRead less