Tools for manipulating neuronal activity for behavioural studies. This project aims to develop optogenetic tools neuroscientists can use to better understand brain circuitry and the functional effects of specific neurons on behaviour. Linking the activity of individual neurons in the brain to specific behaviours is a major challenge in neuroscience. Optogenetics achieve this by using light to control the activity of neurons. This has advanced understanding of behaviour and neurocircuitry. This p ....Tools for manipulating neuronal activity for behavioural studies. This project aims to develop optogenetic tools neuroscientists can use to better understand brain circuitry and the functional effects of specific neurons on behaviour. Linking the activity of individual neurons in the brain to specific behaviours is a major challenge in neuroscience. Optogenetics achieve this by using light to control the activity of neurons. This has advanced understanding of behaviour and neurocircuitry. This project is expected to increase understanding of brain function at the cellular and system levels, and advance Australia’s multidisciplinary research capacity in neuroscience, cognitive sciences and nanobiotechnology to ultimately treat neurological disorders.Read moreRead less
Genetics, genomics and evolution of flowering time control in legumes. Flowering in plants is strongly regulated by environmental factors, with important consequences for their natural distribution and use in agriculture. This project will characterise genes, genetic diversity and molecular mechanisms that control flowering in legumes, contributing to fundamental biology, crop improvement and research training.
Decoding the signals in legume symbioses: investigating the role of plant hormones. Plants form intimate relationships with soil microbes that give plants access to previously unavailable but essential nutrients. Legumes are major Australian crops for fodder, grain and nutrients, and are unique in forming symbioses with both nitrogen-fixing bacteria and with mycorrhizal fungi that supply nutrients such as phosphate. This project aims to determine the role of plant hormones (small, mobile, potent ....Decoding the signals in legume symbioses: investigating the role of plant hormones. Plants form intimate relationships with soil microbes that give plants access to previously unavailable but essential nutrients. Legumes are major Australian crops for fodder, grain and nutrients, and are unique in forming symbioses with both nitrogen-fixing bacteria and with mycorrhizal fungi that supply nutrients such as phosphate. This project aims to determine the role of plant hormones (small, mobile, potent growth regulators) in the formation of these relationships. In particular, the role of interactions between hormones and other novel plant signals will be determined. An insight into the common and divergent roles of hormones in these symbioses is essential to provide new tools to maximise nutrient acquisition.Read moreRead less
Interpreting biological sequence information: untangling hybridisation. Hybridisation is believed to be important during adaptive radiations where species rapidly colonise new niches and respond to new environments, e.g. in times of climate change. This project will create the statistical tools and software required for evolutionary biologists to understand how hybridisation has helped shape the Australian flora.
High performance chromatography based on nanostructured monolithic polymers. The proposed project will generate highly significant, fundamental advances in separation science by developing new stationary phases and separation technologies suitable for the analysis of very complex samples which cannot be addressed by current methods. These technologies will be applied in a wide range of areas of national importance including pharmaceutical analysis and drug discovery; environmental, clinical, and ....High performance chromatography based on nanostructured monolithic polymers. The proposed project will generate highly significant, fundamental advances in separation science by developing new stationary phases and separation technologies suitable for the analysis of very complex samples which cannot be addressed by current methods. These technologies will be applied in a wide range of areas of national importance including pharmaceutical analysis and drug discovery; environmental, clinical, and forensic analysis; energy generation and foods. The project will also lead to very significant new intellectual property having extremely high commercial potential worldwide, and thereby generates the promise of considerable direct financial returns to Australia.Read moreRead less
Bridging the land–sea divide to ensure food security under climate change. This project aims to comprehensively evaluate ocean-based food solutions to meet food security needs under climate change. It will resolve a critical blind spot in current plans that isolate land and sea food systems and neglect their interdependencies. Combining global models and data, it will assess the constraints of ocean-based food solutions by anticipating and accounting for land-sea links including: agricultural ru ....Bridging the land–sea divide to ensure food security under climate change. This project aims to comprehensively evaluate ocean-based food solutions to meet food security needs under climate change. It will resolve a critical blind spot in current plans that isolate land and sea food systems and neglect their interdependencies. Combining global models and data, it will assess the constraints of ocean-based food solutions by anticipating and accounting for land-sea links including: agricultural runoff, shared feed resources for farmed animals, and trade-offs for biodiversity and climate mitigation. It will deliver a major leap in our capacity to undertake holistic ecosystem assessment of future food production pathways. Benefits will include integrated food–biodiversity–climate policies for Australia and the world.Read moreRead less
Upgrading of light gas-to-liquid products to fuels and chemicals. The conversion of natural gas to liquid fuels (gasoline and diesel) is seen as an important alternative to crude oil refining in Australia, and a new industry based around this is likely to emerge in the coming years. This project aims to develop methods by which some of the less valuable by-products can be upgraded to fuels and chemicals.
Can Tasmanian Devils survive by adapting to devil facial tumour disease? This research will examine whether or not Tasmanian Devils are capable of adapting fast enough to survive the disease epidemic caused by a new contagious cancer, devil facial tumour disease, and evade extinction. Outcomes will determine long-term management responses to the disease and will set a benchmark for managing wildlife diseases worldwide.
Urban greening to protect vulnerable people and promote thermal equity. This project aims to create, test and apply new knowledge to promote thermal equity in Australian cities. Climate change is increasing heatwave frequency and intensity as our cities are becoming denser and their populations growing older. Many older people have heightened vulnerability to extreme heat due to income constraints, medical conditions, physical frailty, and reduced mobility. Outputs will include a heat vulnerabil ....Urban greening to protect vulnerable people and promote thermal equity. This project aims to create, test and apply new knowledge to promote thermal equity in Australian cities. Climate change is increasing heatwave frequency and intensity as our cities are becoming denser and their populations growing older. Many older people have heightened vulnerability to extreme heat due to income constraints, medical conditions, physical frailty, and reduced mobility. Outputs will include a heat vulnerability assessment index for identifying at-risk places and vulnerable people, urban tree canopy maps, urban planning policy guidelines for creating cooler cities, and a toolkit for identifying appropriate green infrastructure treatments. Benefits include avoidance of heat-related deaths and improved liveability in cities.Read moreRead less
Faster, greener, stronger: a new approach to synthesis of polymer materials. The project will investigate new approaches towards polymer material synthesis in the complete absence of hazardous solvents, with the aim of creating materials that have superior physical or chemical properties compared to those prepared using existing methods. This project is significant for driving advances in material design and characterization using simple starting materials and environmentally sustainable conditi ....Faster, greener, stronger: a new approach to synthesis of polymer materials. The project will investigate new approaches towards polymer material synthesis in the complete absence of hazardous solvents, with the aim of creating materials that have superior physical or chemical properties compared to those prepared using existing methods. This project is significant for driving advances in material design and characterization using simple starting materials and environmentally sustainable conditions. Expected outcomes include the production of unique nanomaterials, hydrogels and polymer monoliths with targeted applications, in addition to advances in 3D printing. This project will significantly benefit the sustainable material manufacturing industry into the future.Read moreRead less