Dissecting The Pseudoexfoliation Syndrome With Complementary Genetic, Proteomic And Biophysical Strategies
Funder
National Health and Medical Research Council
Funding Amount
$490,352.00
Summary
Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.
Evolutionary, macroecological and phylogenetic patterns in Australasian freshwater crayfish. This project connects Australian systematists to a worldwide project that involves all of the world's living experts on freshwater crayfish evolution in a coordinated effort to answer some very important evolutionary questions. It involves a group of invertebrate animals that are not only readily recognisable, but which in Australia includes the world's largest and the world's most terrestrial crayfish s ....Evolutionary, macroecological and phylogenetic patterns in Australasian freshwater crayfish. This project connects Australian systematists to a worldwide project that involves all of the world's living experts on freshwater crayfish evolution in a coordinated effort to answer some very important evolutionary questions. It involves a group of invertebrate animals that are not only readily recognisable, but which in Australia includes the world's largest and the world's most terrestrial crayfish species. Information gained from the project will contribute to the management of crayfish biodiversity, identification of threatened species and tools to identify these prominent and important members of Australian freshwater ecosystems.Read moreRead less
Understanding the biological functions of the karrikin-responsive signaling system of plants in growth, development and responses to the environment. A new signalling system in plants, related to that of strigolactone hormones but evolutionarily more ancient and functionally distinct, has been discovered. It is defined by the Karrkin-Insensitive-2 (KAI2) protein discovered by its ability to confer responsiveness to karrikins from bushfires. The KAI2 system influences seed germination, and develo ....Understanding the biological functions of the karrikin-responsive signaling system of plants in growth, development and responses to the environment. A new signalling system in plants, related to that of strigolactone hormones but evolutionarily more ancient and functionally distinct, has been discovered. It is defined by the Karrkin-Insensitive-2 (KAI2) protein discovered by its ability to confer responsiveness to karrikins from bushfires. The KAI2 system influences seed germination, and development of seedlings, leaves and potentially roots. This project will use KAI2 mutants and transgenic plants to define the biological functions of KAI2 signalling, and its interactions with other signalling systems. New genes central to KAI2 signalling and responses will be identified for functional analysis. The research will reveal the significance of this new signalling system in plant biology. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100203
Funder
Australian Research Council
Funding Amount
$385,000.00
Summary
Autonomous benthic observing system. This project seeks to improve our ability to monitor marine habitats and characterise their variability by enhancing the Integrated Marine Observing system (IMOS) Autonomous Underwater Vehicle (AUV) Facility. The new AUV infrastructure will reduce operating costs, increase robustness of the sampling effort and insure continued operation for the next decade.
Coupled physical and biogeochemical dynamics on the Australian North West Shelf. Information regarding the natural function of the Australian North West Shelf is urgently required to sustainably manage the often conflicting uses of the region. This project will study the role of ocean processes in driving ocean productivity on the North West Shelf and determine the impact of projected climate variability.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100219
Funder
Australian Research Council
Funding Amount
$170,000.00
Summary
A multi-institutional environmental radioactivity research centre. This project aims to establish an environmental radioactivity research centre, equipped with ultra-low background and high-resolution alpha and gamma spectrometry systems, radon detectors and radium delayed coincidence counters. The centre will address a critical demand in Australia for precise analysis of a large suite of natural and artificial radionuclides, which will be used as tracers and chronological tools to investigate k ....A multi-institutional environmental radioactivity research centre. This project aims to establish an environmental radioactivity research centre, equipped with ultra-low background and high-resolution alpha and gamma spectrometry systems, radon detectors and radium delayed coincidence counters. The centre will address a critical demand in Australia for precise analysis of a large suite of natural and artificial radionuclides, which will be used as tracers and chronological tools to investigate key questions in oceanography and the mining and energy, archaeological, agricultural, and forestry sectors. The facility is expected to substantially increase expertise and training in radionuclides in Australia, and promote high-level research collaborations and outputs of both national and international significance. Major outcomes of the proposed facility include better understanding of how oceans regulate climate and improved capacity to assess effects of radiation on natural ecosystems.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100019
Funder
Australian Research Council
Funding Amount
$580,000.00
Summary
A transportable containerised laboratory for rapid cell sorting and high-resolution bioimaging of living aquatic microbes in field locations. This project will deliver a transportable, unique laboratory for the rapid isolation and high-resolution analysis of living microbes immediately after sampling from the sea or waterways. It will be the first of its kind in Australia and deliver new knowledge of the role of these organisms in their natural habitats.
Enabling social innovation for local climate adaptability. Climate variability and change is likely to be felt most acutely at the local scale in Australia. This is where inter/national and State policies are translated into practices to prepare for, and adapt to, anticipated impacts of heatwaves, bushfires and floods. This project will investigate tensions and potentialities between risk-based assessments by local governance agencies and innovations by local groups and Non-Government Organisati ....Enabling social innovation for local climate adaptability. Climate variability and change is likely to be felt most acutely at the local scale in Australia. This is where inter/national and State policies are translated into practices to prepare for, and adapt to, anticipated impacts of heatwaves, bushfires and floods. This project will investigate tensions and potentialities between risk-based assessments by local governance agencies and innovations by local groups and Non-Government Organisations. The research will utilise an innovative mixed-methods approach to investigate and to analyse the strategies and experiments of adaptation practices. It aims to develop new ways of identifying and implementing practical, local, adaptive responses that are contextually relevant, socially innovative and capacity building.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100029
Funder
Australian Research Council
Funding Amount
$280,000.00
Summary
Ultra-trace analytical facility for earth system change . A new cutting-edge research capability will be established to safe guard Australia's natural resources and environment and to determine past variability in climate. Research results from the facility will help to guide national and international policy makers with regards to sustainable development and management of resources.