Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120102352
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Three-dimensional structural imaging in optical microscopy and tomography. This project will develop fundamentally new strategies for looking inside live cells to determine their internal structures. Such capability will permit a better understanding of diseases, the link between diabetes and heart failure for example, opening the door for new diagnostic techniques and treatments.
Probing antimicrobial drug resistance by multimodal molecular analysis. This project aims to investigate drug resistance in microbial agents. With the emergence of "super bugs" there is a need to understand the biochemistry of antimicrobial resistance. Combining vibrational spectroscopic approaches and metabolomic techniques, the project will investigate cell populations, single cells and subcellular structures in search of biomarkers for drug resistance. The discovery of such biomarkers could l ....Probing antimicrobial drug resistance by multimodal molecular analysis. This project aims to investigate drug resistance in microbial agents. With the emergence of "super bugs" there is a need to understand the biochemistry of antimicrobial resistance. Combining vibrational spectroscopic approaches and metabolomic techniques, the project will investigate cell populations, single cells and subcellular structures in search of biomarkers for drug resistance. The discovery of such biomarkers could lead to improved disease management and eradication programs through identification and treatment of drug resistant pathogens in individuals that have the potential to re-infect the community.Read moreRead less
Radiation detectors to better understand ion interactions. This project aims to build a Heavy Ion Therapy Research and Treatment Centre in Australia. Understanding how ions interact with matter and their radiobiological effectiveness (RBE) is important. The project will introduce an Australian detector technology platform to research ion interaction physics and their RBE. It will develop radiation detectors for ion measurement with a wide energy range, including a practical RBE quality assurance ....Radiation detectors to better understand ion interactions. This project aims to build a Heavy Ion Therapy Research and Treatment Centre in Australia. Understanding how ions interact with matter and their radiobiological effectiveness (RBE) is important. The project will introduce an Australian detector technology platform to research ion interaction physics and their RBE. It will develop radiation detectors for ion measurement with a wide energy range, including a practical RBE quality assurance tool with submillimetre spatial resolution. The proposed Australian radiation detection technology is expected to improve understanding of the scientific mechanisms underpinning the radiobiological effectiveness of heavy ion radiation.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100098
Funder
Australian Research Council
Funding Amount
$1,974,000.00
Summary
Enabling the Future of the Australian Collider Physics Program. The project aims to fund the continuation of Australia’s very successful experimental particle physics program to explore how the universe works at it's fundamental level. We interrogate subatomic matter at the energy frontier at CERN's Large Hadron Collider and the intensity frontier at Japan's SuperKEKB collider. The basic contributions required for Australian membership of these two key programs will enable scientists to continue ....Enabling the Future of the Australian Collider Physics Program. The project aims to fund the continuation of Australia’s very successful experimental particle physics program to explore how the universe works at it's fundamental level. We interrogate subatomic matter at the energy frontier at CERN's Large Hadron Collider and the intensity frontier at Japan's SuperKEKB collider. The basic contributions required for Australian membership of these two key programs will enable scientists to continue capitalising on decades of hard work and accumulated expertise, significant project outcomes and benefits include: access for Australia to advanced instruments and international research facilities; training of the next generation of researchers in detector construction and operation; and a rich science program.Read moreRead less
Bright x-ray beams from laser-driven microplasmas. This project aims to develop a new generation of bright, laser-like x-ray sources for laboratory use. X-ray sources underpin key diagnostic techniques in materials science, advancing applications from structural engineering through to ore processing and energy storage. However, the limited brightness of present-day laboratory x-ray sources restricts the utility and range of these diagnostic techniques. This research intends to use intense lasers ....Bright x-ray beams from laser-driven microplasmas. This project aims to develop a new generation of bright, laser-like x-ray sources for laboratory use. X-ray sources underpin key diagnostic techniques in materials science, advancing applications from structural engineering through to ore processing and energy storage. However, the limited brightness of present-day laboratory x-ray sources restricts the utility and range of these diagnostic techniques. This research intends to use intense lasers to create microscopic plasmas and drive high harmonic generation. The high harmonic generation process is already used to create laser-like ultraviolet light. By optimising the characteristics of the plasma medium, the project aims to extend bright high harmonic generation to the x-ray regime.Read moreRead less
ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting- ....ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting-edge technologies. The Centre will exploit the unique geographical location of the first underground physics lab in the Southern Hemisphere. The ultra-sensitive detectors and ultra-low radiation techniques will translate into a broad range of industrial applications and train a new generation of scientists.Read moreRead less
New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses ....New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses with data libraries to generate precise molecular identification. The outcome is expected to help monitor adulteration of oils and maintain the high quality standards of Australian produce.Read moreRead less