Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of posit ....Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of positron transport in PET. The project will allow validation of predictions from the model by undertaking experiments in liquid water.Read moreRead less
Novel source of excited metastable atoms for Atom Trap Trace Analysis. This project aims to understand and to control light-induced processes in atoms by using finely shaped and tailored laser pulses, focusing on efficient production of excited metastable atoms. This is critical for efficient Atom Trap Trace Analysis, the most advanced technique for dating ground water and geological samples. Expected outcomes of this project include new and enhanced knowledge of physics of light-matter interact ....Novel source of excited metastable atoms for Atom Trap Trace Analysis. This project aims to understand and to control light-induced processes in atoms by using finely shaped and tailored laser pulses, focusing on efficient production of excited metastable atoms. This is critical for efficient Atom Trap Trace Analysis, the most advanced technique for dating ground water and geological samples. Expected outcomes of this project include new and enhanced knowledge of physics of light-matter interactions, developing an efficient, clean source of excited metastable atoms, and integrating that source into the Australian National Facility for dating geological samples. This should provide significant benefits, such as significant improvement of operational efficiency and productivity of that facility.Read moreRead less
ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresour ....ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresources to capitalise upon emergent and rapidly expanding domestic and global markets. Anticipated outcomes include industry uptake of innovative plant forms, foods, technologies, and commodities; and an ambitious education and international co-ordination agenda to position Australia as a global leader in research supporting Space habitation.Read moreRead less
Sewer Monitoring and Management in the Digital Era. Overflow, flooding, corrosion, and odorous emissions are persistent issues for utilities managing sewers. Current sewer maintenance is reactive, and focuses on solving problems in local networks, despite that optimal solutions require a system-wide approach. Capitalising on recent development in IoT sensors, wireless transmission, and machine learning, this multidisciplinary project aims to develop digital-twin supported data analytics for proa ....Sewer Monitoring and Management in the Digital Era. Overflow, flooding, corrosion, and odorous emissions are persistent issues for utilities managing sewers. Current sewer maintenance is reactive, and focuses on solving problems in local networks, despite that optimal solutions require a system-wide approach. Capitalising on recent development in IoT sensors, wireless transmission, and machine learning, this multidisciplinary project aims to develop digital-twin supported data analytics for proactive sewer management including network-wide real-time control. The project aims to generate significant social, environmental and economic benefits by enabling utilities to better protect public and environmental health, reduce sewer odour and greenhouse gas emissions, and extend sewer asset life.Read moreRead less
Reducing direct greenhouse gas emissions from urban wastewater systems. This project aims to develop a systematic framework for water utilities to monitor and reduce direct greenhouse gas (GHG) emissions from wastewater systems. A standardised monitoring protocol will be developed to conduct an unprecedented nationwide sampling campaign. The obtained data, with microbial characterisation and mechanism analysis, will be used to develop novel models for accurate prediction of GHG emissions. Expect ....Reducing direct greenhouse gas emissions from urban wastewater systems. This project aims to develop a systematic framework for water utilities to monitor and reduce direct greenhouse gas (GHG) emissions from wastewater systems. A standardised monitoring protocol will be developed to conduct an unprecedented nationwide sampling campaign. The obtained data, with microbial characterisation and mechanism analysis, will be used to develop novel models for accurate prediction of GHG emissions. Expected outcomes include protocol to accurately monitor emissions, models to predict emission under various conditions, and mitigation guideline for typical plant configurations. The anticipated benefit is a significant reduction in GHG emissions from urban water industry and support it to meet net-zero-emission goal by 2050.Read moreRead less
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100054
Funder
Australian Research Council
Funding Amount
$1,341,398.00
Summary
Dedicated High-throughput 3D-Electron Diffractometer. This proposal aims to install the first dedicated high-throughput 3D-electron diffractometer in the Southern Hemisphere, and one of the first in the world. It will be able to rapidly solve the atomic-scale structures of molecules and materials for which this is now extremely difficult and time-consuming – or impossible – due to the inability to grow large enough crystals for traditional X-ray diffraction. It will thus provide a significant ad ....Dedicated High-throughput 3D-Electron Diffractometer. This proposal aims to install the first dedicated high-throughput 3D-electron diffractometer in the Southern Hemisphere, and one of the first in the world. It will be able to rapidly solve the atomic-scale structures of molecules and materials for which this is now extremely difficult and time-consuming – or impossible – due to the inability to grow large enough crystals for traditional X-ray diffraction. It will thus provide a significant advantage for chemists, physicists, biologists, geologists, and engineers who rely on detailed structural knowledge to rationally optimise the properties of their compounds, from pharmaceutical activity to carbon capture to superconductivity, to the substantial benefit of multiple national priority areas.Read moreRead less
Enabling three dimensional stochastic geological modelling. This project aims to develop technologies to mitigate three dimensional (3D) geological risk in resources management. This project expects to create new knowledge and methods in the field of 3D geological modelling through the innovative application of mathematical methods, structural geology concepts and probabilistic programming. The expected outcomes are an enhanced capability to model the subsurface, characterise model uncertainty a ....Enabling three dimensional stochastic geological modelling. This project aims to develop technologies to mitigate three dimensional (3D) geological risk in resources management. This project expects to create new knowledge and methods in the field of 3D geological modelling through the innovative application of mathematical methods, structural geology concepts and probabilistic programming. The expected outcomes are an enhanced capability to model the subsurface, characterise model uncertainty and test multiple geological scenarios. This enhanced capability is important for the future of Australia's subsurface management, including urban geology and our continuously growing sustainable resources industry.Read moreRead less
Three-dimensional Bayesian Modelling of Geological and Geophysical data. The project aims to develop technologies enabling rapid informed decision-making related to the management of natural resources, including critical metals, copper and water. This new technology will support a greener future, securing our energy future, our access to clean water and reduce the mining footprint. Expected outcomes include an enhanced capability in interoperable, integrated three-dimensional geological and geop ....Three-dimensional Bayesian Modelling of Geological and Geophysical data. The project aims to develop technologies enabling rapid informed decision-making related to the management of natural resources, including critical metals, copper and water. This new technology will support a greener future, securing our energy future, our access to clean water and reduce the mining footprint. Expected outcomes include an enhanced capability in interoperable, integrated three-dimensional geological and geophysical modelling in order to predictively characterise sub-surface geology. The outcome will be an open-source forecasting dashboard enabling decision making while considering underlying risk related to resource extractions and management with significant benefits to the Australian society (lower emissions, clean water).Read moreRead less