Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
ARC Centre of Excellence - Centre for Antimatter-Matter Studies. While our world is made of matter, all particles have anti-particles and the most abundant is the positron, the electron's antiparticle. It is the "workshop" for most anti-matter studies, particularly for the characterization of materials, including gases, polymers, insulators, thin films and surfaces, as well as the development of new and novel, nano-structured materials. The ARC Centre of Excellence in Antimatter-Matter Studies ....ARC Centre of Excellence - Centre for Antimatter-Matter Studies. While our world is made of matter, all particles have anti-particles and the most abundant is the positron, the electron's antiparticle. It is the "workshop" for most anti-matter studies, particularly for the characterization of materials, including gases, polymers, insulators, thin films and surfaces, as well as the development of new and novel, nano-structured materials. The ARC Centre of Excellence in Antimatter-Matter Studies (CAMS) will bring together key Australian and international scientists to work in this emerging scientific field of antimatter-matter interactions. It will forge a unique and effective scientific team for state-of-the-art studies of the nano-world that underlies many everyday processes and new technologies.Read moreRead less
Mental health, job quality and workforce participation: evidence from population health research to address complex problems and conflicting policies. Mental disorders such as depression are a major cause of disability. Improving mental health can increase productivity and workforce participation. However, the psychosocial quality of work is a factor that overlays the relationship between work and health. Poor quality work (for example, unreasonable time pressure, insecurity) increases the risk ....Mental health, job quality and workforce participation: evidence from population health research to address complex problems and conflicting policies. Mental disorders such as depression are a major cause of disability. Improving mental health can increase productivity and workforce participation. However, the psychosocial quality of work is a factor that overlays the relationship between work and health. Poor quality work (for example, unreasonable time pressure, insecurity) increases the risk of poor mental health, absenteeism, and exit from the workforce. This project will analyse data following people over time to investigate the long-term health and employment consequences of poor psychosocial job quality, and consider the special case of mature age workers. It will identify those individuals at greatest risk, and factors that can buffer against the adverse effects of poor quality work.Read moreRead less
Working longer, staying healthy and keeping productive. Working longer, staying healthy and keeping productive. This project aims to develop a policy suite to respond to an older workforce. By 2060, nearly half of Australians aged 64 or older will be employed. Failure to address their health problems could threaten Australia’s economy, tax base and provision of health and care services. This collaboration between national policy portfolios (employment, social services, workplace health and socia ....Working longer, staying healthy and keeping productive. Working longer, staying healthy and keeping productive. This project aims to develop a policy suite to respond to an older workforce. By 2060, nearly half of Australians aged 64 or older will be employed. Failure to address their health problems could threaten Australia’s economy, tax base and provision of health and care services. This collaboration between national policy portfolios (employment, social services, workplace health and social equity) and expert scientists in work, health, social equality and policy process intends to reveal the diversity of older workers’ work-health dilemmas and effective ways for national policies to solve them. The policy suite will promote financial independence and meet social goals of equity and healthy ageing.Read moreRead less
Interaction Mining for Cyberbullying Detection on Social Networks. This project plans to build an interactive mining system to detect cyberbullying on social networks that have a large number of participants and a variety of inputs, including conversation texts, time-variant changes and user profiles. The project is designed to change the existing cyberbullying prevention services from reactive keyword filtering to proactive social interaction pattern mining. The intended outcome will enable the ....Interaction Mining for Cyberbullying Detection on Social Networks. This project plans to build an interactive mining system to detect cyberbullying on social networks that have a large number of participants and a variety of inputs, including conversation texts, time-variant changes and user profiles. The project is designed to change the existing cyberbullying prevention services from reactive keyword filtering to proactive social interaction pattern mining. The intended outcome will enable the early detection and warning of cyberbullying and approach open a new way to discover interaction patterns with a large number of participants over evolving and complex social networks.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668398
Funder
Australian Research Council
Funding Amount
$177,900.00
Summary
Advanced Microwave Facility for Quantum-Atom Optics. Atoms can be controlled using light in visible and infra-red regions, as well as electromagnetic waves of longer wavelength in the microwave (MW) and radiofrequency (RF) part of the spectrum. We presently use optical radiation to control atoms at the quantum level where they can behave like waves and can interact with light to store and manipulate information. The MW and RF facility will extend our abilities and enable more complete control of ....Advanced Microwave Facility for Quantum-Atom Optics. Atoms can be controlled using light in visible and infra-red regions, as well as electromagnetic waves of longer wavelength in the microwave (MW) and radiofrequency (RF) part of the spectrum. We presently use optical radiation to control atoms at the quantum level where they can behave like waves and can interact with light to store and manipulate information. The MW and RF facility will extend our abilities and enable more complete control of the atoms, which will help us develop the first generation quantum technology. This will enable the creation of quantum devices such as atom lasers, atom interferometers and quantum information networks for communication and ultra-sensitive measurement applications.Read moreRead less
Creating pathways to child wellbeing in disadvantaged communities. This project aims to test, in nine disadvantaged communities, a model for action that blends new human and digital resources to support respectful, data-driven collaborations between schools, families and community agencies.
The project expects to generate new knowledge in the area of translational prevention science about how to influence risk and protective factors for child wellbeing in a cost-efficient manner and at a scale ....Creating pathways to child wellbeing in disadvantaged communities. This project aims to test, in nine disadvantaged communities, a model for action that blends new human and digital resources to support respectful, data-driven collaborations between schools, families and community agencies.
The project expects to generate new knowledge in the area of translational prevention science about how to influence risk and protective factors for child wellbeing in a cost-efficient manner and at a scale within existing service systems. Project benefits should include a methodology for achieving lasting improvements in child wellbeing, behaviour and school success.
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Industrial Transformation Training Centres - Grant ID: IC140100027
Funder
Australian Research Council
Funding Amount
$2,150,000.00
Summary
ARC Training Centre for Functional Grains. ARC Training Centre for Functional Grains. The Training Centre aims to improve the profitability of the Australian grains industry. It plans to achieve this by adding value to rice, canola and pulses through: the development of a better understanding of market opportunities; improving storage technologies; the development of products which improve returns to the industry and result in better health outcomes for consumers; and improving processing method ....ARC Training Centre for Functional Grains. ARC Training Centre for Functional Grains. The Training Centre aims to improve the profitability of the Australian grains industry. It plans to achieve this by adding value to rice, canola and pulses through: the development of a better understanding of market opportunities; improving storage technologies; the development of products which improve returns to the industry and result in better health outcomes for consumers; and improving processing methods to generate these products.Read moreRead less
ARC Centre of Excellence for Translational Photosynthesis. The ARC Centre of Excellence for Translational Photosynthesis seeks to develop and harness advances in photosynthesis research, crop bioengineering, plant phenomics and computational tools to realise increased and sustainable crop yields, opening new routes to achieving the next revolution in plant productivity. It will deliver improved yield by undertaking a continuum of fundamental and applied photosynthesis research and targeting proj ....ARC Centre of Excellence for Translational Photosynthesis. The ARC Centre of Excellence for Translational Photosynthesis seeks to develop and harness advances in photosynthesis research, crop bioengineering, plant phenomics and computational tools to realise increased and sustainable crop yields, opening new routes to achieving the next revolution in plant productivity. It will deliver improved yield by undertaking a continuum of fundamental and applied photosynthesis research and targeting projects with a high probability of producing increased yield. Links with national and international institutions, consortia and breeding companies will enhance the prospects of translating genetic improvements into crops such as wheat, rice and sorghum for improved yield.Read moreRead less
The use of molecular sponges to inhibit small Ribonucleic acid activity in plants. The deletion of gene activity is the most powerful way to understand gene function; however for genes encoding small Ribonucleic acids (RNAs) no current methodology can efficiently achieve this. Here, we aim to develop a gene silencing technology for small RNA encoding genes, which can be utilised to determine their function and used for biotechnological applications.