In-field sensors for the detection of illicit drugs. Presumptive field test kits for illicit drugs analysis are typically based on chemical spot tests that produce a coloured product. While relatively easy to apply, such test kits (containing wet chemicals) produce inconclusive colour changes lacking sensitivity, and selectivity requiring a subjective assessment by the examiner. Despite these limitations, these test kits are in widespread use and are routinely used. This study aims to develop s ....In-field sensors for the detection of illicit drugs. Presumptive field test kits for illicit drugs analysis are typically based on chemical spot tests that produce a coloured product. While relatively easy to apply, such test kits (containing wet chemicals) produce inconclusive colour changes lacking sensitivity, and selectivity requiring a subjective assessment by the examiner. Despite these limitations, these test kits are in widespread use and are routinely used. This study aims to develop specific in-field sensors for the detection and identification of illicit drugs. This would significantly enhance the ability of Forensic Services staff to confirm the identity of seized material. Increased specificity would provide valuable early advice to investigators regarding the nature of a seizure and would reduce the likelihood of false positive results. Increased sensitivity would permit the analysis of trace amounts of material from individuals or locations related to an illicit drug consignment.Read moreRead less
Single Molecule Studies of Replisomal Function. It has recently become possible to watch the copying of DNA molecules with a specialized microscope in real time. This process requires assembly of a complex molecular machine on the DNA, followed by triggering of its function, and yields exquisitely detailed information about how the machine works. In this new collaboration between scientists in Australia and the U.S.A., we will assemble these machines on single DNA molecules, watch how they work ....Single Molecule Studies of Replisomal Function. It has recently become possible to watch the copying of DNA molecules with a specialized microscope in real time. This process requires assembly of a complex molecular machine on the DNA, followed by triggering of its function, and yields exquisitely detailed information about how the machine works. In this new collaboration between scientists in Australia and the U.S.A., we will assemble these machines on single DNA molecules, watch how they work and simultaneously measure the very small forces that the machines generate. This will give Australian scientists access to a new technology for studying molecular machines.Read moreRead less
Engineered nanoassmblies for energy conversion. This research will lead to development of clean energy technology that can compete with the traditional energy sources without subsidies, and facilitate long-term solution to the energy crisis and global warming. It will also bring significant benefit to Australian industries and economy and assist achievement of renewable energy target.
Discovery and applications of circular proteins. The many national benefits that will flow from this program include (i) new knowledge in plant biochemistry, peptide chemistry and protein engineering protected by a strong intellectual property position that will give Australia a competitive edge in relevant biotechnology applications; (ii) the training of a new generation of skilled researchers to drive a sustainable biotechnology sector in Australia; (iii) economic benefits from royalty returns ....Discovery and applications of circular proteins. The many national benefits that will flow from this program include (i) new knowledge in plant biochemistry, peptide chemistry and protein engineering protected by a strong intellectual property position that will give Australia a competitive edge in relevant biotechnology applications; (ii) the training of a new generation of skilled researchers to drive a sustainable biotechnology sector in Australia; (iii) economic benefits from royalty returns on drugs and agricultural products that will likely arise from the program; (iv) environment benefits due to a reduced need for chemical insecticides; and (v) social benefits due to a reduction in suffering from diseases for which drugs are developed as a result of this program.Read moreRead less
Development of Methods and Strategies for the Measurement, Interpretation and Analysis of Diffuse X-ray Scattering from Disordered Materials. This application seeks to exploit our established lead in the measurement of diffuse scattering from disordered materials and its analysis using large-scale computer simulations. Many industrially important materials such as ceramics, superconductors, catalysts, electro-optical materials and minerals owe their special properties to the disorder in their st ....Development of Methods and Strategies for the Measurement, Interpretation and Analysis of Diffuse X-ray Scattering from Disordered Materials. This application seeks to exploit our established lead in the measurement of diffuse scattering from disordered materials and its analysis using large-scale computer simulations. Many industrially important materials such as ceramics, superconductors, catalysts, electro-optical materials and minerals owe their special properties to the disorder in their structure. This disorder causes diffuse X-ray scattering which can be probed using synchrotron X-rays and powerful computers to reveal details about the material's nanoscale structure. The new methodology being developed will enhance our detailed understanding of the relationships between structure and properties in materials and help promote the design of new materials. Read moreRead less
Next generation supramolecular frameworks. This project aims to prepare new supramolecular frameworks assembled by hydrogen or halogen bonds. It is anticipated that this work will increase fundamental understanding of supramolecular self-assembly processes and the dynamic processes that are possible within these rearrangeable systems. The project aims to prepare a family of related frameworks, which will allow a detailed comparison of the stability, porosity and biotechnological applicability of ....Next generation supramolecular frameworks. This project aims to prepare new supramolecular frameworks assembled by hydrogen or halogen bonds. It is anticipated that this work will increase fundamental understanding of supramolecular self-assembly processes and the dynamic processes that are possible within these rearrangeable systems. The project aims to prepare a family of related frameworks, which will allow a detailed comparison of the stability, porosity and biotechnological applicability of new supramolecular materials. The expected outcomes are the development of lightweight and benign organic systems that will have applications in the removal of toxic organic and heavy metal pollutants from water, and in the encapsulation and stabilisation of catalytically-active enzymes.Read moreRead less
Supramolecular Assemblies as Nanoscale Devices to Control Chemical and Physical Processes. The aims of this project are: i) to develop molecular reaction vessels to enhance the rates and control the outcomes of chemical processes; ii) to design and construct supramolecular species with a range of topologies; and iii) to explore the potential use of these supramolecular assemblies as thermal and photochemical switches and molecular tweezers, and as the basis for molecular machines and microelectr ....Supramolecular Assemblies as Nanoscale Devices to Control Chemical and Physical Processes. The aims of this project are: i) to develop molecular reaction vessels to enhance the rates and control the outcomes of chemical processes; ii) to design and construct supramolecular species with a range of topologies; and iii) to explore the potential use of these supramolecular assemblies as thermal and photochemical switches and molecular tweezers, and as the basis for molecular machines and microelectronic devices. The research is expected to provide new and efficient methods for bench-top and industrial scale synthesis of chemicals in water, as well as fundamental advances in nanotechnology to underpin new industries based on advanced materials.Read moreRead less
Naturally derived photoinitiators for biocompatible 3D printing. This project aims to develop an environmentally-friendly approach to naturally derived photoinitiators which are applicable to 3D printing through low-energy, visible light-induced polymerisation, and explore their application in the fabrication of biocompatible polymeric materials. Traditional polymer manufacturing processes such as thermopolymerisation employ hazardous chemicals which present health and environmental risks. This ....Naturally derived photoinitiators for biocompatible 3D printing. This project aims to develop an environmentally-friendly approach to naturally derived photoinitiators which are applicable to 3D printing through low-energy, visible light-induced polymerisation, and explore their application in the fabrication of biocompatible polymeric materials. Traditional polymer manufacturing processes such as thermopolymerisation employ hazardous chemicals which present health and environmental risks. This project expects to expand fundamental scientific knowledge of photochemistry, polymer chemistry and biology through the development of a novel, economical, clean, commercially-relevant platform (3D printing) for the fabrication of polymeric materials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100147
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
Advanced ultrasonic spray deposition system for large area solar cells fabrication. Low cost, low carbon forms of power generation are required to enable Australia to minimise its greenhouse gas emissions. Traditional solar cells are manufactured using high cost, low volume production methods which will in future be complemented by the introduction of low cost, high volume printed organic solar cells. Spray deposition of active materials will allow the formation of active solar cells on many n ....Advanced ultrasonic spray deposition system for large area solar cells fabrication. Low cost, low carbon forms of power generation are required to enable Australia to minimise its greenhouse gas emissions. Traditional solar cells are manufactured using high cost, low volume production methods which will in future be complemented by the introduction of low cost, high volume printed organic solar cells. Spray deposition of active materials will allow the formation of active solar cells on many new materials, thus opening up new ways of using solar cells and hence new markets or export opportunities. The research is aimed at delivering a local research-driven industry which is export-oriented, thus assisting Australia to reach its carbon reduction targets.Read moreRead less