Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346891
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Characterization facilities for new macromolecular architectures. The proposed facility is essential for characterization of the new polymeric architectures such as copolymers for tissue engineering, nanogels for automotive paints and biodegradable polymeric packaging. The facilities include characterizations of (1) molar mass and molecular sizes of novel polymer architectures (MU); (2) viscoelastic mechanical properties of tensile, bending, bulk and flow (RMIT); and (3) thermal properties of c ....Characterization facilities for new macromolecular architectures. The proposed facility is essential for characterization of the new polymeric architectures such as copolymers for tissue engineering, nanogels for automotive paints and biodegradable polymeric packaging. The facilities include characterizations of (1) molar mass and molecular sizes of novel polymer architectures (MU); (2) viscoelastic mechanical properties of tensile, bending, bulk and flow (RMIT); and (3) thermal properties of compositions (CSIRO). These new polymeric architectures cannot be sufficiently characterized by existing facilities. The success of the project will significantly enhance the new macromolecular research and facilitate collaborations. This project also falls within the nano and biomaterials of the Designated Priority area of Research.Read moreRead less
Building advanced polymeric nanotubes for targeted drug delivery. Advanced drug delivery devices have major commercial applications in fighting diseases like cancer and infectious viruses. The success of this project will provide fundamental knowledge for the design of new drug delivery devices based on polymeric nanotubes. The project will also further advance Australia's nano- and bio-technological research and industries. This project will also provide additional benefit for developing contro ....Building advanced polymeric nanotubes for targeted drug delivery. Advanced drug delivery devices have major commercial applications in fighting diseases like cancer and infectious viruses. The success of this project will provide fundamental knowledge for the design of new drug delivery devices based on polymeric nanotubes. The project will also further advance Australia's nano- and bio-technological research and industries. This project will also provide additional benefit for developing controlled release systems in drug delivery and artificial vessels, and improve sensitivity in molecular sensors. The pioneering work proposed will ensure that Australia remains at the forefront of innovative scientific research within the rapidly advancing disciplines of nanotechnology and novel macromolecular design.Read moreRead less
Atomic scale precision engineering of cell-material interfaces. This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and cell membranes through x-ray diffraction and molecular simulation. The project will generate knowledge to enable atomic scale engineering of peptide nanomaterials, and exploitation of these materials to modulate cell responses. Expected outcomes include designed peptide nanostructures with specific chemical and physical ....Atomic scale precision engineering of cell-material interfaces. This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and cell membranes through x-ray diffraction and molecular simulation. The project will generate knowledge to enable atomic scale engineering of peptide nanomaterials, and exploitation of these materials to modulate cell responses. Expected outcomes include designed peptide nanostructures with specific chemical and physical cues to promote sustainable growth of desired cells, whilst inhibiting undesirable responses. These outcomes should provide benefits in terms of a practical toolkit for tailoring structure and function of peptide nanostructures and open up a new era in molecular design of smart biomaterials. This easily scalable, new materials platform will contribute to emerging high-value manufacturing industries in Australia.Read moreRead less
ARC Centre of Excellence in Exciton Science. This Centre aims to manipulate the way light energy is absorbed, transported and transformed in advanced molecular materials. The research programme spans high-throughput computational screening, single molecule photochemistry and ultrafast spectroscopy and embraces innovative outreach and commercial translation activities. The Centre plans to capture the knowledge generated as new intellectual property, materials processing know-how, and through the ....ARC Centre of Excellence in Exciton Science. This Centre aims to manipulate the way light energy is absorbed, transported and transformed in advanced molecular materials. The research programme spans high-throughput computational screening, single molecule photochemistry and ultrafast spectroscopy and embraces innovative outreach and commercial translation activities. The Centre plans to capture the knowledge generated as new intellectual property, materials processing know-how, and through the creation of new employment opportunities. The expected outcomes and benefits include new Australian technologies in solar energy conversion, energy-efficient lighting and displays, security labelling and optical sensor platforms for defence.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100161
Funder
Australian Research Council
Funding Amount
$407,598.00
Summary
Translational Design: Product Development for Research Commercialisation. Australia is a world leader in fundamental research. Yet, ranks as one of the worst developed nations for translating research into new-to-market innovation. This project explores a new role for design as a critical component of research commercialisation and innovation ecosystems. It expects to contribute novel insights into how designers can be better integrated into interdisciplinary research directed towards commercial ....Translational Design: Product Development for Research Commercialisation. Australia is a world leader in fundamental research. Yet, ranks as one of the worst developed nations for translating research into new-to-market innovation. This project explores a new role for design as a critical component of research commercialisation and innovation ecosystems. It expects to contribute novel insights into how designers can be better integrated into interdisciplinary research directed towards commercial outcomes. Expected outcomes include a framework and toolkit for a paradigm-shifting design approach to translating fundamental research into products commercialised and manufactured in Australia. This should provide enhanced economic benefit, building Australia’s sovereign capability in new-to-market innovation.Read moreRead less
Advanced adsorbents for gas separations. Efficient purification of natural gas and separation of similarly-sized molecules in gas mixtures is increasingly important in our drive to develop a more sustainable way of living in an energy-constrained world. This project will develop a new class of adsorbents to deliver a level of separation efficiency much higher than that currently in use.
Designing for wellbeing: realizing benefits for patients through best practice hospital design. The environmental design of healthcare facilities has been shown to directly affect the wellbeing of patients and their families. Poorly designed environments exacerbate patient anxiety and stress and diminish their healthcare experience. Environments designed to support a patient’s wellbeing result in improved health outcomes. Building upon Australia’s international leadership in contemporary hospita ....Designing for wellbeing: realizing benefits for patients through best practice hospital design. The environmental design of healthcare facilities has been shown to directly affect the wellbeing of patients and their families. Poorly designed environments exacerbate patient anxiety and stress and diminish their healthcare experience. Environments designed to support a patient’s wellbeing result in improved health outcomes. Building upon Australia’s international leadership in contemporary hospital design, this project aims to evaluate, prioritise and strategise the best means for realising benefits of environmental design factors that contribute most significantly to achieving positive outcomes for patients and families. It aims to achieve this through a comprehensive comparative case study analysis of new Australian paediatric hospitals.Read moreRead less
Unravelling Efficient Nucleic Acid Delivery Using Multilayer Nanoparticles. Developing smarter nanoparticles is critical for maximising the potential of biological therapeutics such as nucleic acids. Currently, the efficiency of nanoparticle delivery remains low due to the inability of carriers to migrate different biological regions. The aim of this project is to develop responsive polymer nanoparticles that can more effectively migrate cell barriers by a two-staged release based on the combina ....Unravelling Efficient Nucleic Acid Delivery Using Multilayer Nanoparticles. Developing smarter nanoparticles is critical for maximising the potential of biological therapeutics such as nucleic acids. Currently, the efficiency of nanoparticle delivery remains low due to the inability of carriers to migrate different biological regions. The aim of this project is to develop responsive polymer nanoparticles that can more effectively migrate cell barriers by a two-staged release based on the combination of different self-immolative polymers. This project will allow the development of design rules for understanding how nanoparticle structure can be optimised to improve nucleic acid delivery. This work will have important benefits such as developing new nanotechnology industry and skilled graduates for Australia.
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Developing vitrimers: next generation reusable plastics. This project aims to develop a new class of advanced multifunctional polymer materials with the potential to underpin significant breakthrough capabilities for soft materials in general. The proposed work will relocate biological catalysts from their native, wet environment to solid organic engineering bio-sourced resins. Suitably selected enzymes will allow creation of polymer-based products that can be fully recyclable, with built-in pro ....Developing vitrimers: next generation reusable plastics. This project aims to develop a new class of advanced multifunctional polymer materials with the potential to underpin significant breakthrough capabilities for soft materials in general. The proposed work will relocate biological catalysts from their native, wet environment to solid organic engineering bio-sourced resins. Suitably selected enzymes will allow creation of polymer-based products that can be fully recyclable, with built-in properties such as self-healing, shape morphing, which are mechanically tunable, and have the ability to be reprocessed/recycled multiple times. This research will initiate a disruptive change in the application of biocatalysts for bio-based polymers.Read moreRead less
Digital fabrication technologies: analysing patterns of adoption and innovative transformations in architectural design and practice. This project on adoption of digital fabrication technologies by Australian architecture practices will reveal emerging opportunities for creative design and associated transformations in the design practices. These outcomes will enable the increasingly globalising sector of architectural design services to become more agile and innovative.