Aspirin For The Prevention Of Cognitive Decline In The Elderly: A Neuro-Vascular Imaging Study (ENVIS-ion) From ASPREE
Funder
National Health and Medical Research Council
Funding Amount
$1,341,232.00
Summary
The ENVIS-ion trial will examine whether Aspirin is effective in delaying the onset of worsening of thinking and memory abilities in healthy older adults. Magnetic resonance imaging (MRI) of brain structure will detect markers of early worsening of thinking and memory abilities. Blood vessels in the back of the eye (retina) share many features with vessels in the brain. We will compare whether aspirin lessens changes over time of features shown with brain MRI and retinal photography.
The Role Of Intense Physical Activity In Protecting The Ageing Brain
Funder
National Health and Medical Research Council
Funding Amount
$600,079.00
Summary
Previous research supports the notion that physical activity plays a role in maintaining brain health and preventing Alzheimer’s disease. Nevertheless, the type of activity (i.e. intensity of physical activity) that is of greatest benefit to the brain is yet to be established. This project aims to identify the most beneficial exercise intensity, in terms of brain health, measured utilising brain imaging technology.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100124
Funder
Australian Research Council
Funding Amount
$538,590.00
Summary
An Advanced Ultrafast Laser Spectroscopy Facility in Queensland. The project aims to establish a world-class ultrafast laser spectroscopy facility to investigate how molecules interact with visible or ultraviolet light. Light-matter interactions are key to energy generation in nature through photosynthesis as well as everyday technologies including optical communications and displays. This project expects to generate new knowledge in on how light interacts with matter at the molecular level. Exp ....An Advanced Ultrafast Laser Spectroscopy Facility in Queensland. The project aims to establish a world-class ultrafast laser spectroscopy facility to investigate how molecules interact with visible or ultraviolet light. Light-matter interactions are key to energy generation in nature through photosynthesis as well as everyday technologies including optical communications and displays. This project expects to generate new knowledge in on how light interacts with matter at the molecular level. Expected outcomes of the ultrafast spectroscopic measurements will be understanding the fate of light absorbed by or generated in different materials. Application of the knowledge gained will enable the design of materials for more efficient technologies such as solar cells, lighting, and sensors.Read moreRead less
Magnetic Nanostructures for Emerging Technologies: Experimental and Theoretical studies. This project enables collaborations between Australian and European groups in an important and expanding area at the forefront of technology, and facilitates access to state of the art resources in laboratories in Austria and Spain. It carries across knowledge in synchrotron techniques just at the right time, just before the Australian synchrotron goes on line in 2008, allowing time to deepen expertise and t ....Magnetic Nanostructures for Emerging Technologies: Experimental and Theoretical studies. This project enables collaborations between Australian and European groups in an important and expanding area at the forefront of technology, and facilitates access to state of the art resources in laboratories in Austria and Spain. It carries across knowledge in synchrotron techniques just at the right time, just before the Australian synchrotron goes on line in 2008, allowing time to deepen expertise and to obtain specific knowledge. It will help establish a new effort at the University of Western Australia concentrated on developing advanced materials for technology. We will make important contributions to an internationally important area and offer high quality interdisciplinary research training in magnetic nanomaterials science.Read moreRead less
Fast and slow dynamics at coupled magnetic interfaces: Theory and Experiment. Immediate needs for advances in materials for spin electronics and information technology require a deeper physical understanding of new materials in which interfaces and nanometre dimensions determine properties. Interfacial exchange coupling between magnetic layers is a key issue in the formation of many multilayer structures, and several important issues remain unresolved. This is a proposal for a joint theoretical ....Fast and slow dynamics at coupled magnetic interfaces: Theory and Experiment. Immediate needs for advances in materials for spin electronics and information technology require a deeper physical understanding of new materials in which interfaces and nanometre dimensions determine properties. Interfacial exchange coupling between magnetic layers is a key issue in the formation of many multilayer structures, and several important issues remain unresolved. This is a proposal for a joint theoretical and experimental study of technologically important magnetic interfaces by groups at Universities of Florence, Perugia, Leeds and Western Australia.Read moreRead less
Energetics and dynamics of solvated biologically relevant molecules using liquid microjet and ion imaging technologies. The shape of many biomolecules in solution plays a critical role in determining their biological activity and function. It is known that the bonds that form between the biomolecules and the water solvent control this shape. However, very little is known about the strength and structure of these bonds at different sites around the biomolecule. Many experiments have informed u ....Energetics and dynamics of solvated biologically relevant molecules using liquid microjet and ion imaging technologies. The shape of many biomolecules in solution plays a critical role in determining their biological activity and function. It is known that the bonds that form between the biomolecules and the water solvent control this shape. However, very little is known about the strength and structure of these bonds at different sites around the biomolecule. Many experiments have informed us about the strength of the bonds, others have told us where the bonds occur. This project will provide both pieces of information for the first time, allowing us to better understand, and therefore control, biological function. This work will assist in the development of new biotechnology processes, especially in the emerging area of proteomics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989127
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
A High-Throughput Neutron Spectrometer for The Study of Atomic and Molecular Motion at ANSTO. Neutron scattering enables new science across a broad range of disciplines, and for this reason it is undergoing major expansion in the USA, Europe, Japan and Australia. Various diffactometers and spectrometers have recently been built at ANSTO, but an instrumental option for a high-throughput cross-discipline spectroscopy is urgently needed. Fortunately, it is fairly straightforward to add this type of ....A High-Throughput Neutron Spectrometer for The Study of Atomic and Molecular Motion at ANSTO. Neutron scattering enables new science across a broad range of disciplines, and for this reason it is undergoing major expansion in the USA, Europe, Japan and Australia. Various diffactometers and spectrometers have recently been built at ANSTO, but an instrumental option for a high-throughput cross-discipline spectroscopy is urgently needed. Fortunately, it is fairly straightforward to add this type of option to an existing spectrometer that will broaden its user-base from specialised applications in physics to more general applications in physics, chemistry, materials-science and biology. This additional option provides a totally new way for Australian scientists to study atomic and molecular motions. Read moreRead less
Time and frequency resolved magnetometry. Magnetism is well known as a source of fundamental unsolved problems in material physics and condensed matter. It is also an area famous for practical application: the ability to record and read information from magnetic materials is the basis of nearly all mass data storage devices. The aim of this project is to provide first measures of certain key energies and rates associated with magnetic processes. Through a combination of theoretical modelling and ....Time and frequency resolved magnetometry. Magnetism is well known as a source of fundamental unsolved problems in material physics and condensed matter. It is also an area famous for practical application: the ability to record and read information from magnetic materials is the basis of nearly all mass data storage devices. The aim of this project is to provide first measures of certain key energies and rates associated with magnetic processes. Through a combination of theoretical modelling and experiment design, a new experimental technique will be developed into a powerful analysis tool. This work will establish the technique in Australia and create new opportunities for future study.
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Theoretical and experimental studies of exchange bias in thin films. Films containing layers of different types of magnetic materials - in particular, ferromagnetic and antiferromagnetic - have properties which are being exploited in magneto-electronic devices used in recording and manipulation of computer data. These properties are determined by new types of magnetisation processes in the interface between layers. In this project investigations of the magnetic behaviour of interfaces will be ma ....Theoretical and experimental studies of exchange bias in thin films. Films containing layers of different types of magnetic materials - in particular, ferromagnetic and antiferromagnetic - have properties which are being exploited in magneto-electronic devices used in recording and manipulation of computer data. These properties are determined by new types of magnetisation processes in the interface between layers. In this project investigations of the magnetic behaviour of interfaces will be made to provide information of value in the design and optimisation of new and existing devices. The procedures to be developed in this project will be applicable to the understanding of the behaviour of a new range of atomically engineered magnetic structures.Read moreRead less