ENU Mutagenesis To Identify Targets For Host-directed Therapy Against Malaria.
Funder
National Health and Medical Research Council
Funding Amount
$660,175.00
Summary
Malaria kills up to one million people annually, mainly children and pregnant women. The drugs that are used to treat malaria are becoming useless due to the malarial parasite developing resistance to these drugs. We are looking at a totally new way of developing drugs that target molecules in humans , depriving the parasites of crucial factors. By using this approach, the malaria parasite will be unable to develop resistance to these new drugs and millions of lives may be saved.
High Resolution Genome-wide SNP Analysis Of Genetic Alterations In Early Ovarian Neoplasms
Funder
National Health and Medical Research Council
Funding Amount
$587,055.00
Summary
Ovarian cancer is the 5th leading cause of cancer death in women. For such a significant disease, remarkably little is know about its origins and this has limited progress in developing more effective diagnostic markers. We will undertake cutting edge genome-wide analysis of pre-invasive ovarian tumours to identify genetic markers relevant to malignancy. This work will significantly expand our understanding of how ovarian cancers develops.