Improving the wool product. Using mathematical modelling to improve the efficiency of wool scouring. Our aim is to improve the quality of scoured wool by improving the efficiency of wool scouring. Wool scouring is the process of washing greasy wool once it has been removed from the sheep's back. After being rinsed to remove sweat and salt the wool is passed through a scour bowl consisting of settling tanks from which dirty water is periodically expelled. Mathematical modelling will optimise us ....Improving the wool product. Using mathematical modelling to improve the efficiency of wool scouring. Our aim is to improve the quality of scoured wool by improving the efficiency of wool scouring. Wool scouring is the process of washing greasy wool once it has been removed from the sheep's back. After being rinsed to remove sweat and salt the wool is passed through a scour bowl consisting of settling tanks from which dirty water is periodically expelled. Mathematical modelling will optimise use of the scour bowl, reduce consumption of water, increase the recovery of wool grease and improve the quality and cleanliness of the wool.Read moreRead less
Material boundaries in ultrasonics: New methods and in vitro studies in biomedical phantoms. Ultrasound is an indispensable part of healthcare worldwide. The next wave of applications will see ultrasound pulses used to closely probe suspected disease sites and to directly manipulate bioactive agents. For safe and effective use of such techniques it is essential to know the ultrasound field at the disease site. This project will develop simulation methods to achieve the fast, accurate and case-sp ....Material boundaries in ultrasonics: New methods and in vitro studies in biomedical phantoms. Ultrasound is an indispensable part of healthcare worldwide. The next wave of applications will see ultrasound pulses used to closely probe suspected disease sites and to directly manipulate bioactive agents. For safe and effective use of such techniques it is essential to know the ultrasound field at the disease site. This project will develop simulation methods to achieve the fast, accurate and case-specific results required. Community healthcare will benefit, through better diagnostic capabilities and customized treatment. Australia is well placed to profit further from this research, in view of the growing worldwide demand for more sophisticated, knowledge-based techniques in medicine.Read moreRead less
The effect of vessel wall structures on ultrasonic flow velocity measurements. The flow velocity within a nearly cylindrical vessel is often measured using an external ultrasound transducer via the Doppler principle. Thick vessel walls may present acoustically mismatched structures. This project aims to determine how such walls redistribute the energy in an interrogating ultrasound beam, and how this in turn affects the measurement of flow velocities. This is a fundamental issue, especially imp ....The effect of vessel wall structures on ultrasonic flow velocity measurements. The flow velocity within a nearly cylindrical vessel is often measured using an external ultrasound transducer via the Doppler principle. Thick vessel walls may present acoustically mismatched structures. This project aims to determine how such walls redistribute the energy in an interrogating ultrasound beam, and how this in turn affects the measurement of flow velocities. This is a fundamental issue, especially important in vascular disease where blood flow and blood vessels are affected by wall irregularities and lesions. The new knowledge generated by this project will have practical importance and, by identifying achievable outcomes, potentially major cost savings, in medical ultrasound.Read moreRead less
Efficient Operation of Bioreactors using Nonlinear Dynamical Systems Theory. Current methods of determining optimal operating conditions in bioreactors have recently been shown to be inefficient, resulting in serious omissions of crucial parameter regions. We will use mathematical techniques from dynamical systems theory to establish a general framework by which bioreactor systems can be efficiently and systematically investigated to improve reactor performance. By communicating these results at ....Efficient Operation of Bioreactors using Nonlinear Dynamical Systems Theory. Current methods of determining optimal operating conditions in bioreactors have recently been shown to be inefficient, resulting in serious omissions of crucial parameter regions. We will use mathematical techniques from dynamical systems theory to establish a general framework by which bioreactor systems can be efficiently and systematically investigated to improve reactor performance. By communicating these results at relevant fora, we will increase the awareness within the Australian and international engineering communities of the advantages of modern mathematical techniques. Although this proposal focuses on bioreactors, the techniques can be easily adapted to improve the performances of other chemical processes.
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Special Research Initiatives - Grant ID: SR0354741
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Quantum Many-Body Systems Network: Breakthrough Science and Frontier Technologies. This Initiative will bring together leading researchers with complementary expertise in mathematics and the enabling sciences to form a Network fostering world leading fundamental research and innovation in quantum many-body systems. The collaborative effort between mathematicians with powerful and sophisticated new techniques and physicists and chemists with deep insight into the challenges and opportunities of t ....Quantum Many-Body Systems Network: Breakthrough Science and Frontier Technologies. This Initiative will bring together leading researchers with complementary expertise in mathematics and the enabling sciences to form a Network fostering world leading fundamental research and innovation in quantum many-body systems. The collaborative effort between mathematicians with powerful and sophisticated new techniques and physicists and chemists with deep insight into the challenges and opportunities of the quantum realm will lead to breakthrough science of vital importance to the development of frontier technologies in Australia. This Network will also place a strong emphasis on research training, the mentoring of early career researchers and establishing collaborations with leading international research groups and networks.
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Statistical and computational methods using a multiscale approach for protein identification and quantification. Proteins are critically important in the onset and ongoing illness associated with disease. Key proteins may serve as markers to diagnose or predict the course of a disease, or even become the target of pharmaceuticals. Accurate, efficient and robust algorithms are a critical component in protein identification. This research provides novel statistical algorithms for protein identific ....Statistical and computational methods using a multiscale approach for protein identification and quantification. Proteins are critically important in the onset and ongoing illness associated with disease. Key proteins may serve as markers to diagnose or predict the course of a disease, or even become the target of pharmaceuticals. Accurate, efficient and robust algorithms are a critical component in protein identification. This research provides novel statistical algorithms for protein identification using multiscale analysis techniques. Their applications in the bio-medical field will enable Australian and international researchers to identify key proteins more accurately, than current methods, leading to improve health, medical, and biological research outcomes.Read moreRead less
New statistical methods for identifying micro-ribonucleic acid (miRNA) regulatory networks. Understanding gene regulatory networks is critical in the understanding of fundamental biological systems. These networks have important implications for the discovery of fundamental mechanisms relating to the diagnosis and management of many illnesses. This research will provide new statistical methods to identify regulatory micro-ribonucleic acid modules and to understand their relationship in gene regu ....New statistical methods for identifying micro-ribonucleic acid (miRNA) regulatory networks. Understanding gene regulatory networks is critical in the understanding of fundamental biological systems. These networks have important implications for the discovery of fundamental mechanisms relating to the diagnosis and management of many illnesses. This research will provide new statistical methods to identify regulatory micro-ribonucleic acid modules and to understand their relationship in gene regulatory networks through multiple covariance estimation and multivariate classification techniques. My results should enable researchers to better understand the regulation underlying biological systems, leading to improved human health, medical and biological research outcomes.Read moreRead less
Diffusion driven pattern formation and signal propagation in spatially complex excitable media. A basic understanding of the mechanisms for pattern formation, from the spots on leopards to electrical signalling of neurons, has been achieved through reaction-diffusion equations. However to obtain a complete understanding, which is vital for many applications, it is necessary to modify this mathematical model to incorporate spatial complexities in the underlying media. This project will develop ....Diffusion driven pattern formation and signal propagation in spatially complex excitable media. A basic understanding of the mechanisms for pattern formation, from the spots on leopards to electrical signalling of neurons, has been achieved through reaction-diffusion equations. However to obtain a complete understanding, which is vital for many applications, it is necessary to modify this mathematical model to incorporate spatial complexities in the underlying media. This project will develop a fractional calculus framework for pattern formation, including signal propagation, in spatially complex and excitable media. In a particular application we will model the way in which the signalling properties of neurons depend critically on their spatial complexity.Read moreRead less
Analysing Instabilities in Complex Combustion Models for Different Geometrical Configurations. Anyone who has gazed into a fire will appreciate the complexity of combustion. To date only the simplest of models have been comprehensively analysed. This project, which aims to analyse more complex combustion models, will address some of the fundamental issues of combustion theory. Results from this project will lead to a better understanding of combustion processes, with the potential to prevent exp ....Analysing Instabilities in Complex Combustion Models for Different Geometrical Configurations. Anyone who has gazed into a fire will appreciate the complexity of combustion. To date only the simplest of models have been comprehensively analysed. This project, which aims to analyse more complex combustion models, will address some of the fundamental issues of combustion theory. Results from this project will lead to a better understanding of combustion processes, with the potential to prevent explosions in reactors and storage tanks. Other potential applications range from bushfires to the manufacture of exotic materials. Furthermore, the novel mathematical techniques developed in this project can be easily adapted to other types of systems such as those used in biology (eg. epidemiology and tumour growth), economics, physics etc. Read moreRead less
Mathematical and mechanical models in nano-engineering and nanomedicine. The major environmental problems generated from global warming and the major human health problems, like cancer and diabetes, if they are to be solved at all, will most likely be resolved making use of advances in nanobiotechnology. This proposal will position Australia as a leader in the modelling of nanodevices such as gigahertz oscillators, nano-electromagnets, nanosensors, nanosyringes and nanoporous media suitable for ....Mathematical and mechanical models in nano-engineering and nanomedicine. The major environmental problems generated from global warming and the major human health problems, like cancer and diabetes, if they are to be solved at all, will most likely be resolved making use of advances in nanobiotechnology. This proposal will position Australia as a leader in the modelling of nanodevices such as gigahertz oscillators, nano-electromagnets, nanosensors, nanosyringes and nanoporous media suitable for hydrogen storage and gas separation, which will lead to new technologies and commercial spin-offs that will be of major benefit to this country. The applicants will develop a range of topics in nano-engineering and nanomedicine, training a team that will provide the next generation of researchers in these vital areas.Read moreRead less