Optimal shapes in geometry and physics: Isoperimetry in modern analysis. This project will find the best isoperimetric shapes in curved spaces: shapes that optimise geometric or analytic quantities, such as the volume enclosed by a surface of a given area, or the resonant frequency of a drum of given area. The optimal shapes lead to tools that are widely used in differential equations, geometric analysis, statistical physics, probability theory, and quantum computing. Through this work, we ....Optimal shapes in geometry and physics: Isoperimetry in modern analysis. This project will find the best isoperimetric shapes in curved spaces: shapes that optimise geometric or analytic quantities, such as the volume enclosed by a surface of a given area, or the resonant frequency of a drum of given area. The optimal shapes lead to tools that are widely used in differential equations, geometric analysis, statistical physics, probability theory, and quantum computing. Through this work, we will forge connections between the geometry of curved spaces, and the physics of operators therein. The significant benefits of this project include increasing fundamental mathematical knowledge, building capacity in Australia’s world-class geometric analysis community, and strong links with international partners.Read moreRead less
Enumeration and properties of large discrete structures. This project aims to study a fundamental property of random graphs, by further developing a recently introduced approach to the problem of enumerating graphs with given degrees. Using this new method, the project expects to generate new knowledge on the number of connections that each node has with other nodes in a random graph, and to develop new strategies for counting the graphs or networks with a given property. The project expects to ....Enumeration and properties of large discrete structures. This project aims to study a fundamental property of random graphs, by further developing a recently introduced approach to the problem of enumerating graphs with given degrees. Using this new method, the project expects to generate new knowledge on the number of connections that each node has with other nodes in a random graph, and to develop new strategies for counting the graphs or networks with a given property. The project expects to produce new theoretical results as well as enhanced capabilities of mathematical research. Potential benefits arise through the uses of these theoretical combinatorial objects to study naturally occurring networks such as social networks, the network of the world wide web, and chemical compounds.Read moreRead less
Enumeration and random generation of contingency tables with given margins. This project aims to find algorithms to construct random tables of numbers having given totals across the rows and down the columns. The aim is also to study properties of such tables. A significant aspect of the project is that it is expected to cover scenarios where all existing methods fail, by deploying recently developed powerful techniques used for random networks in combinatorics. Expected outcomes of this project ....Enumeration and random generation of contingency tables with given margins. This project aims to find algorithms to construct random tables of numbers having given totals across the rows and down the columns. The aim is also to study properties of such tables. A significant aspect of the project is that it is expected to cover scenarios where all existing methods fail, by deploying recently developed powerful techniques used for random networks in combinatorics. Expected outcomes of this project include the development of efficient algorithms that can be used in statistics for identifying relationships between variables in large data sets. This would help bring Australia to the forefront of research in an area that is significant both in data analysis and in discrete mathematics.
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Unpacking the immune system with applied mathematics. This project aims to model immune interactions across cells and structures spanning scales of nanometres to millimetres. It expects to develop innovative mathematical insights, improve our understanding of immunology, and consolidate collaborations with top American and European laboratories and groups. Expected outcomes include cutting-edge techniques for multiscale biological modelling and improved prediction and analysis of immune dynami ....Unpacking the immune system with applied mathematics. This project aims to model immune interactions across cells and structures spanning scales of nanometres to millimetres. It expects to develop innovative mathematical insights, improve our understanding of immunology, and consolidate collaborations with top American and European laboratories and groups. Expected outcomes include cutting-edge techniques for multiscale biological modelling and improved prediction and analysis of immune dynamics. The project should provide benefits to industries where highly organised behaviours are important, for example those interested in robot swarming, optimal transportation, and epidemic management. It should also benefit Australian students and researchers with novel overseas training opportunities.Read moreRead less
Computational methods for population-size-dependent branching processes. Branching processes are the primary mathematical tool used to model populations that evolve randomly in time. Most key results in the theory are derived under the simplifying assumption that individuals reproduce and die independently of each other. However, this assumption fails in most real-life situations, in particular when the environment has limited resources or when the habitat has a restricted capacity. This project ....Computational methods for population-size-dependent branching processes. Branching processes are the primary mathematical tool used to model populations that evolve randomly in time. Most key results in the theory are derived under the simplifying assumption that individuals reproduce and die independently of each other. However, this assumption fails in most real-life situations, in particular when the environment has limited resources or when the habitat has a restricted capacity. This project aims to develop novel and effective algorithmic techniques and statistical methods for a class of branching processes with dependences. We will use these results to study significant problems in the conservation of endangered island bird populations in Oceania, and to help inform their conservation management.Read moreRead less
Empirical and computational solutions for multi-omics single-cell assays. Emerging single-cell sequencing technologies are transforming molecular cell biology, but identifying novel cell types and their functions requires the integration of highly heterogeneous data. The development of computational methods able to extract biologically relevant results is hindered by the lack of high-quality datasets. This project aims to develop novel sequencing methodologies and generate data to drive our dime ....Empirical and computational solutions for multi-omics single-cell assays. Emerging single-cell sequencing technologies are transforming molecular cell biology, but identifying novel cell types and their functions requires the integration of highly heterogeneous data. The development of computational methods able to extract biologically relevant results is hindered by the lack of high-quality datasets. This project aims to develop novel sequencing methodologies and generate data to drive our dimension reduction multivariate method developments for data integration. By combining in silico and in vivo approaches, the project is anticipated to benefit scientists willing to work in cutting-edge single-cell research by providing useful protocols and tools to generate novel insights in cell biology. Read moreRead less
New universality in stochastic systems. This project aims to uncover new analyses and effects in the complex behaviour of non-linear systems with random noise. Many systems originate near an unstable equilibrium. This project will develop a new mathematical theory that establishes a universality in the way the long term effect of noise expresses itself as random initial conditions in the dynamics. It will fill gaps in Mathematics and make refinements to existing fundamental scientific laws by in ....New universality in stochastic systems. This project aims to uncover new analyses and effects in the complex behaviour of non-linear systems with random noise. Many systems originate near an unstable equilibrium. This project will develop a new mathematical theory that establishes a universality in the way the long term effect of noise expresses itself as random initial conditions in the dynamics. It will fill gaps in Mathematics and make refinements to existing fundamental scientific laws by including random initial conditions as predicted by our theory. This will advance our understanding of complex systems subjected to noise and will provide significant benefits in the scientific discoveries in Biology, Ecology, Physics and other Sciences where such systems are frequently met.Read moreRead less
Algorithms for Future-Proof Networks. This project will design algorithms to construct, augment and route on geometric graphs in the presence of obstacles. Such graphs have many real-world applications, including transport networks. This project aims to give solutions with hard guarantees on the timeliness of the delivery of the people, goods, or information being transported in these networks. Expected outcomes of this project include efficient and innovative algorithms for realistic geometric ....Algorithms for Future-Proof Networks. This project will design algorithms to construct, augment and route on geometric graphs in the presence of obstacles. Such graphs have many real-world applications, including transport networks. This project aims to give solutions with hard guarantees on the timeliness of the delivery of the people, goods, or information being transported in these networks. Expected outcomes of this project include efficient and innovative algorithms for realistic geometric graphs, which both advances the knowledge in this field of computer science and make our existing networks more reliable. This should provide significant benefits in the maintenance and utilisation of the communication and transport networks we use every day.Read moreRead less
Gravity and quantum-limited measurements with a fundamental minimum length. This project aims to investigate the effects of a fundamental minimum length on the nature of gravity and on how accurately we can make measurements in our world. The key challenge is to combine our best theories of fundamental physics to model what happens at ultra-short distances. This project will generate new knowledge at this interface by using a novel approach inspired by information theory. The expected outcomes a ....Gravity and quantum-limited measurements with a fundamental minimum length. This project aims to investigate the effects of a fundamental minimum length on the nature of gravity and on how accurately we can make measurements in our world. The key challenge is to combine our best theories of fundamental physics to model what happens at ultra-short distances. This project will generate new knowledge at this interface by using a novel approach inspired by information theory. The expected outcomes are new connections between fundamental limitations on measurements, the nature of gravitation, and ultra-small-scale quantum physics. The benefit of this work is breaking the logjam in answering the most important open question in all of physics: how to unite quantum theory and gravitation.Read moreRead less
The shape of chaos: geometric advances in partially hyperbolic dynamics. This project aims to use recent advances in geometry and topology to discover new forms of chaotic dynamical systems and further classify the forms of chaos which are possible. Many systems in nature exhibit chaotic dynamics as they change in time. Not all systems are chaotic in the same way, and identifying the form of chaos and its qualitative properties is crucial to truly understanding the system. Chaotic dynamics aris ....The shape of chaos: geometric advances in partially hyperbolic dynamics. This project aims to use recent advances in geometry and topology to discover new forms of chaotic dynamical systems and further classify the forms of chaos which are possible. Many systems in nature exhibit chaotic dynamics as they change in time. Not all systems are chaotic in the same way, and identifying the form of chaos and its qualitative properties is crucial to truly understanding the system. Chaotic dynamics arise in chemical reactions, celestial mechanics, industrial mixing processes, fusion reactors, and many other processes. This project will aid in predicting the possible long-term behaviours of these systems.Read moreRead less