Improving Pain And Movement Outcomes In Symptomatic Knee Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
People fear getting painful knee osteoarthritis (OA) more than any other disease – it is seen as progressive and incurable. It often stops people from moving and staying healthy, resulting in an enormous burden on sufferers and the health care system. This program of research aims to understand what brain & nervous system processes might underlie these pain and movement problems and whether new brain-targeting treatment helps. This will allow us to better match treatment to what patients need.
Surface engineering of oriented nano-layers for performance control. This research project will deliver knowledge on how to graft oriented, self assembled films from a surface, develop structure-property relationships at a nano-scale, develop a means to control these properties and develop characterization techniques at nano-scales. This research project, if successful, will deliver the ability to tailor the properties of a surface in a manner and over a range of properties that is not even cont ....Surface engineering of oriented nano-layers for performance control. This research project will deliver knowledge on how to graft oriented, self assembled films from a surface, develop structure-property relationships at a nano-scale, develop a means to control these properties and develop characterization techniques at nano-scales. This research project, if successful, will deliver the ability to tailor the properties of a surface in a manner and over a range of properties that is not even contemplated today.
In addition to the scientific benefits, there are also immediate commercial applications in Australia and worldwide for ophthalmic products (e.g. anti-fog and easy to clean lenses), if the balance of properties can be obtained.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100236
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Facilities for spectroscopy and diffraction at high pressures. The provision of infrastructure for the study of novel materials under high pressures will enhance Australia's capability in creating new materials and in creating new devices that meet needs in communication, environment and medicine applications. The new facility will enable researchers to understand the response of structures to extreme pressures and will exploit the unique capabilities of the synchrotron light.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453832
Funder
Australian Research Council
Funding Amount
$550,910.00
Summary
New directions in biomolecular mass spectrometry. The combined UoW/ANU mass spectrometry facility supports a range of research projects in high priority areas including proteomics, mechanisms of aging, anticancer drugs and pathogenicity. The facility has several key deficiencies: 1) the ability to study very high molecular weight biomolecular complexes, 2) the ability to study ion-molecule interactions that have implications in mechanisms of chemistry in nature, and 3) researchers at ANU lack es ....New directions in biomolecular mass spectrometry. The combined UoW/ANU mass spectrometry facility supports a range of research projects in high priority areas including proteomics, mechanisms of aging, anticancer drugs and pathogenicity. The facility has several key deficiencies: 1) the ability to study very high molecular weight biomolecular complexes, 2) the ability to study ion-molecule interactions that have implications in mechanisms of chemistry in nature, and 3) researchers at ANU lack essential walk-up access to high sensitivity protein sequence analysis (MS/MS). The placement of resources that address these deficiencies in one geographical region and collaboration between these institutions will produce a research interaction unique in Australia.Read moreRead less