Highly Efficient Solar Window Technology Enabled by Quantum Dots. The transition to zero-greenhouse gas emitting buildings is hindered by the lack of efficient energy generating building components with good aesthetics. This project will develop integrated solar windows that can effectively convert the facades of urban buildings into energy generation sites, enabled by our nanomaterials having outstanding light emission efficiencies of over 90%, accompanied by our advanced light guiding strategi ....Highly Efficient Solar Window Technology Enabled by Quantum Dots. The transition to zero-greenhouse gas emitting buildings is hindered by the lack of efficient energy generating building components with good aesthetics. This project will develop integrated solar windows that can effectively convert the facades of urban buildings into energy generation sites, enabled by our nanomaterials having outstanding light emission efficiencies of over 90%, accompanied by our advanced light guiding strategies and innovative PV cell integration. This next generation technology can reduce the electricity cost and increase renewable energy adoption, placing Australia in a competitive position in the billion-dollar building integrated photovoltaic market whilst also contributing to decarbonising electricity generation.Read moreRead less
Coproantigen detection tests for diagnosis of intestinal parasitic nematode infection. The aim of this project is to develop new tests for detection of hookworm and Strongyloides, two common intestinal worm infections of humans. These tests offer the potential to replace current tests, namely stool microscopy and serodiagnosis, both of whose performance is unsatisfactory due to deficiencies in sensitivity, specificity and operator convenience. The tests will rely on monoclonal antibodies to dete ....Coproantigen detection tests for diagnosis of intestinal parasitic nematode infection. The aim of this project is to develop new tests for detection of hookworm and Strongyloides, two common intestinal worm infections of humans. These tests offer the potential to replace current tests, namely stool microscopy and serodiagnosis, both of whose performance is unsatisfactory due to deficiencies in sensitivity, specificity and operator convenience. The tests will rely on monoclonal antibodies to detect parasite products in stool. Such testing technology is amenable to configuration in a robust format, suitable for large-scale manufacture. Given the worldwide prevalence of these parasites, the tests will have a market potential of international significance.Read moreRead less
Targeting the undruggable: epitope mapping using Phylomers peptides to modulate activity of Transcription Factors. This project aims at expanding the pool of drug targets, by extending drug screening to protein-protein interaction networks. This project aims to assemble a novel technical platform to detect binding between proteins, using a combination of cell-free protein expression, AlphaScreen and single-molecule fluorescence. This pipeline has great potential to accelerate the exploration of ....Targeting the undruggable: epitope mapping using Phylomers peptides to modulate activity of Transcription Factors. This project aims at expanding the pool of drug targets, by extending drug screening to protein-protein interaction networks. This project aims to assemble a novel technical platform to detect binding between proteins, using a combination of cell-free protein expression, AlphaScreen and single-molecule fluorescence. This pipeline has great potential to accelerate the exploration of protein networks, and provides also a generic platform for drug screening on difficult targets. The project intends to screen Phylogica's libraries of peptides called Phylomers to discover tight binders to a Transcription Factor, Sox18. The objective of this project is to determine which Phylomers can disrupt specific interactions between Sox18 and its binding partners involved in lymphangiogenesis.Read moreRead less
A microfluidic array of phylomers for rapid discovery of peptide probes and biomarkers. This project, through an alliance with Phylogica, aims at exploiting a unique source of structural diversity for drug discovery, harvesting the creativity of nature in its most exotic places. The project will develop a novel approach to validate design and validate drug candidates, by gathering them on a single screening chip for a powerful discovery platform.
High performance metal oxide inks for printable memory arrays . This project aims to develop next generation printable memory devices with low cost and excellent stability. The goal will be achieved by developing a new class of metal oxide nanomaterials based inks and large scale printing technology, through optimizing the synthesis, printing process and electrode configuration. The expected outcomes will be new electronic materials for a wide range of end uses in flexible electronics, significa ....High performance metal oxide inks for printable memory arrays . This project aims to develop next generation printable memory devices with low cost and excellent stability. The goal will be achieved by developing a new class of metal oxide nanomaterials based inks and large scale printing technology, through optimizing the synthesis, printing process and electrode configuration. The expected outcomes will be new electronic materials for a wide range of end uses in flexible electronics, significant advances in energy efficient data storage devices, and commercialisation of the technology to Australian industries.Read moreRead less
Integrated on-chip force and displacement sensors for high-speed atomic force microscopy of ultimate sensitivity. This project aims to develop next generation atomic force microscopy systems based on a novel interferometric method for on-chip force and displacement sensing. The proposed sensitivity improvement of two orders of magnitude over the present state-of-the-art will provide a disruptive innovation for various present and future nanotechnologies.
INTEGRATED PASSIVE AND ACTIVE CONTROL OF HUMMING NOISE FROM KCGM’S HAUL TRUCKS. This project aims to resolve an environmental noise issue caused by the humming noise of Kalgoorlie Consolidated Gold Mines haul trucks in the areas of Kalgoorlie, Boulder, and Williamstown. This solution utilises integrated passive and active control systems to attenuate the frequency components of humming noise from a truck’s exhaust and engine. A novel aspect of this technique is the use of passive micro-perforate ....INTEGRATED PASSIVE AND ACTIVE CONTROL OF HUMMING NOISE FROM KCGM’S HAUL TRUCKS. This project aims to resolve an environmental noise issue caused by the humming noise of Kalgoorlie Consolidated Gold Mines haul trucks in the areas of Kalgoorlie, Boulder, and Williamstown. This solution utilises integrated passive and active control systems to attenuate the frequency components of humming noise from a truck’s exhaust and engine. A novel aspect of this technique is the use of passive micro-perforated structures to provide the necessary sound absorption capability and to alter the sound propagation and radiation properties of the truck exhaust and engine, and increase the effectiveness of active control.Read moreRead less
Troublesome ticks: a new molecular toolkit to investigate zoonotic tick-borne pathogens in Australia. This project will use the latest molecular diagnostic techniques to address unanswered questions about potential tick-transmitted diseases of humans and companion animals in Australia. The study will identify 'hot-spots' for tick-borne pathogens, identify areas of potential risk for humans, and investigate vector-host-pathogen interactions nationwide.
Ecology and transmission of tick-borne disease in Australia. Ecology and transmission of tick-borne disease in Australia. This project aims to determine the bacterial, protozoal and viral biodiversity in wildlife ticks and their native mammal hosts, and provide new information about the biology and transmission dynamics of these microorganisms and their potential to cause disease in wildlife, domesticated animals and humans. Anticipated outcomes are improved diagnostic tests and management proto ....Ecology and transmission of tick-borne disease in Australia. Ecology and transmission of tick-borne disease in Australia. This project aims to determine the bacterial, protozoal and viral biodiversity in wildlife ticks and their native mammal hosts, and provide new information about the biology and transmission dynamics of these microorganisms and their potential to cause disease in wildlife, domesticated animals and humans. Anticipated outcomes are improved diagnostic tests and management protocols for tick-borne disease in Australia.Read moreRead less