X-Ray Activation of Photocatalytic Titania-Coated Biomedical Implants in Situ. The main causes of biomedical implant failure are loosening and infection, which may require revision surgery. The project has the potential to solve these widespread and expensive problems by formation of a coating of strongly (chemically) bonded and photocatalytically active titania on the titanium implant surface and short-term low-dose X-irradiation. This work has the potential to provide the biomedical industry w ....X-Ray Activation of Photocatalytic Titania-Coated Biomedical Implants in Situ. The main causes of biomedical implant failure are loosening and infection, which may require revision surgery. The project has the potential to solve these widespread and expensive problems by formation of a coating of strongly (chemically) bonded and photocatalytically active titania on the titanium implant surface and short-term low-dose X-irradiation. This work has the potential to provide the biomedical industry with a revolutionary development in both implant coating design and quality with self-disinfection capacity after implantation.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100128
Funder
Australian Research Council
Funding Amount
$670,000.00
Summary
Helium and neon ion microscope for sub nanometer imaging and fabrication. The project's proposed instrument would add a new desperately needed capability to Australia's high resolution microscopy centre and nano fabrication facility and enable a wide range of users to image, measure, build and design complex nanostructures at the atomic level and upwards.
Coproantigen detection tests for diagnosis of intestinal parasitic nematode infection. The aim of this project is to develop new tests for detection of hookworm and Strongyloides, two common intestinal worm infections of humans. These tests offer the potential to replace current tests, namely stool microscopy and serodiagnosis, both of whose performance is unsatisfactory due to deficiencies in sensitivity, specificity and operator convenience. The tests will rely on monoclonal antibodies to dete ....Coproantigen detection tests for diagnosis of intestinal parasitic nematode infection. The aim of this project is to develop new tests for detection of hookworm and Strongyloides, two common intestinal worm infections of humans. These tests offer the potential to replace current tests, namely stool microscopy and serodiagnosis, both of whose performance is unsatisfactory due to deficiencies in sensitivity, specificity and operator convenience. The tests will rely on monoclonal antibodies to detect parasite products in stool. Such testing technology is amenable to configuration in a robust format, suitable for large-scale manufacture. Given the worldwide prevalence of these parasites, the tests will have a market potential of international significance.Read moreRead less
Targeting the undruggable: epitope mapping using Phylomers peptides to modulate activity of Transcription Factors. This project aims at expanding the pool of drug targets, by extending drug screening to protein-protein interaction networks. This project aims to assemble a novel technical platform to detect binding between proteins, using a combination of cell-free protein expression, AlphaScreen and single-molecule fluorescence. This pipeline has great potential to accelerate the exploration of ....Targeting the undruggable: epitope mapping using Phylomers peptides to modulate activity of Transcription Factors. This project aims at expanding the pool of drug targets, by extending drug screening to protein-protein interaction networks. This project aims to assemble a novel technical platform to detect binding between proteins, using a combination of cell-free protein expression, AlphaScreen and single-molecule fluorescence. This pipeline has great potential to accelerate the exploration of protein networks, and provides also a generic platform for drug screening on difficult targets. The project intends to screen Phylogica's libraries of peptides called Phylomers to discover tight binders to a Transcription Factor, Sox18. The objective of this project is to determine which Phylomers can disrupt specific interactions between Sox18 and its binding partners involved in lymphangiogenesis.Read moreRead less
A microfluidic array of phylomers for rapid discovery of peptide probes and biomarkers. This project, through an alliance with Phylogica, aims at exploiting a unique source of structural diversity for drug discovery, harvesting the creativity of nature in its most exotic places. The project will develop a novel approach to validate design and validate drug candidates, by gathering them on a single screening chip for a powerful discovery platform.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100094
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Selective laser melting - an advanced manufacturing and physical modelling technology for the digital age. Selective laser melting is a new manufacturing technology that creates parts layer by layer directly from a computer model, eliminating the need for tooling or machining. This technology will be applied to a diverse range of research areas from producing the next generation of medical implants and devices to improving our understanding of geo-materials.
A Skin Detection Micro-Sensor for Face Identification using Color and Stereo Information. The objective of this research is to develop a micro-sensor for face identification, using color and stereo information. The micro-sensor chip performs a real-time search of the scene to locate human skin for subsequent face detection. This micro-sensor could also be used for gesture recognition, lip reading, monitoring driver's hypo-vigilance or tracking a person in a crowd. The chip image-recognition capa ....A Skin Detection Micro-Sensor for Face Identification using Color and Stereo Information. The objective of this research is to develop a micro-sensor for face identification, using color and stereo information. The micro-sensor chip performs a real-time search of the scene to locate human skin for subsequent face detection. This micro-sensor could also be used for gesture recognition, lip reading, monitoring driver's hypo-vigilance or tracking a person in a crowd. The chip image-recognition capabilities will spur the development of a new generation of consumer products with "intelligent eyes".
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100159
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
National facility for biased target deposition of alloyed nanolayers. This facility will enhance Australia's strengths and capabilities in fabricating structures, with applications in multiple research fields including opto-magneto-electronics, next generation lithium ion batteries and energy nanogenerators. It will enhance Australia's research profile as a leader in nanotechnology.
Special Research Initiatives - Grant ID: SR0354735
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Australian Network on Microelectronics, Optoelectronics and Microelectromechanical Systems. The Network will encompass semiconductor microelectronics, optoelectronics, sensors and microelectromechanical systems (MEMS). Fundamental research in these areas enables the technological advances that underpin rapidly developing industries such as information and telecommunications technologies, defence, aerospace, medicine, and remote sensing. Exciting challenges exist in designing new devices that exp ....Australian Network on Microelectronics, Optoelectronics and Microelectromechanical Systems. The Network will encompass semiconductor microelectronics, optoelectronics, sensors and microelectromechanical systems (MEMS). Fundamental research in these areas enables the technological advances that underpin rapidly developing industries such as information and telecommunications technologies, defence, aerospace, medicine, and remote sensing. Exciting challenges exist in designing new devices that exploit unique semiconductor systems and technologies. By sharing capabilities and resources (both capital and human), the network will enable the issues associated with such novel materials and devices to be addressed in a targeted manner. The network will also guarantee the ongoing future of research in the area by actively involving early career researchers and postgraduate students.Read moreRead less
Levelling the Playing Field: Starting with the School Playground. This project aims to demonstrate the effectiveness of simple, cost-effective programs for changing the way parents and teachers view manageable risk-taking for children with disabilities and increasing the level of responsibility that children take for their own actions. The well-being of all children with disabilities is at risk and the gap continues to widen. New programs, such as the National Disability Insurance Scheme, will p ....Levelling the Playing Field: Starting with the School Playground. This project aims to demonstrate the effectiveness of simple, cost-effective programs for changing the way parents and teachers view manageable risk-taking for children with disabilities and increasing the level of responsibility that children take for their own actions. The well-being of all children with disabilities is at risk and the gap continues to widen. New programs, such as the National Disability Insurance Scheme, will place increasing demands on young people with disabilities. Innovative approaches are desperately. Such programming must begin early, by including children in an age-appropriate ways and simultaneously addressing the issues of adults who have the most significant influence: parents and teachers.Read moreRead less