Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100001
Funder
Australian Research Council
Funding Amount
$410,000.00
Summary
Collaborative advanced spectroscopy facility for materials and devices. Collaborative advanced spectroscopy facility for materials and devices: This project aims to enable advancements in electronics, photonics, biomedicine, and sensing through a collaborative, open access facility for advanced optical and chemical spectroscopy of thin films, materials, and devices. The intended capabilities include high-speed, precise and state-of-the-art spectroscopy tools which enable in situ characterisation ....Collaborative advanced spectroscopy facility for materials and devices. Collaborative advanced spectroscopy facility for materials and devices: This project aims to enable advancements in electronics, photonics, biomedicine, and sensing through a collaborative, open access facility for advanced optical and chemical spectroscopy of thin films, materials, and devices. The intended capabilities include high-speed, precise and state-of-the-art spectroscopy tools which enable in situ characterisation at sub-micron scales and cryogenic temperatures, under bio-simulated environments, down to single pixel resolution, with parallel imaging and spectroscopy, and of fluids and biomaterials. The instrumentation will include cryogenic sub-micron photoluminescence and micro-Raman spectroscopy, single pixel optical and dark field spectroscopy, continuous wave terahertz time-domain spectroscopy, wide wavelength microscopic spectroscopy, and temperature-jump kinetics spectroscopy. It is expected that these complementary instruments will accelerate research in materials and devices for plasmonics, nanoelectronics, biomedicine, biochemistry, security, and forensic science.Read moreRead less
Virtual testing of orthopaedic devices as part of the design and development process: strategies to account for patient and surgical variability. Novel computational tools will be developed through this project to help account for patient and surgical variability in the design of orthopaedic implants, such as hip and knee replacements and spinal products. These tools will reduce the design time, give greater insight in implant performance and ultimately lead to safer implants with improved longe ....Virtual testing of orthopaedic devices as part of the design and development process: strategies to account for patient and surgical variability. Novel computational tools will be developed through this project to help account for patient and surgical variability in the design of orthopaedic implants, such as hip and knee replacements and spinal products. These tools will reduce the design time, give greater insight in implant performance and ultimately lead to safer implants with improved longevity.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100175
Funder
Australian Research Council
Funding Amount
$347,070.00
Summary
Three-dimensional additive bio-fabrication facility: printing bioprinters. This project aims to develop bioprinting systems that will provide new insights into fundamental biological processes. The 3D Additive Bio-Fabrication Facility - Printing Bioprinters capability will use 3D polymer and metal additive manufacturing technologies to create the next generation of bioprinting methodologies and 3D fabrication tools. It is the aim that these customised additive manufacturing systems will be used ....Three-dimensional additive bio-fabrication facility: printing bioprinters. This project aims to develop bioprinting systems that will provide new insights into fundamental biological processes. The 3D Additive Bio-Fabrication Facility - Printing Bioprinters capability will use 3D polymer and metal additive manufacturing technologies to create the next generation of bioprinting methodologies and 3D fabrication tools. It is the aim that these customised additive manufacturing systems will be used to produce structures wherein living cells are spatially organised in combination with appropriate biomaterials and bioactive components, such as drugs or growth factors, in order to influence subsequent biological behaviour.Read moreRead less
Surface Engineered Biomaterials to Control Inflammation. The overarching aim of this project is to provide a mechanistic understanding of how surface nanotopography affects inflammatory responses. Experimental evidence demonstrates that engineered surface nanotopography in combination with surface chemistry downregulates the expression of proinflammatory cytokines from primary macrophages. The significance of these findings is that it may be possible to engineer the nanotopography of a biomedica ....Surface Engineered Biomaterials to Control Inflammation. The overarching aim of this project is to provide a mechanistic understanding of how surface nanotopography affects inflammatory responses. Experimental evidence demonstrates that engineered surface nanotopography in combination with surface chemistry downregulates the expression of proinflammatory cytokines from primary macrophages. The significance of these findings is that it may be possible to engineer the nanotopography of a biomedical device surface in a manner which leads to a desired and predictable level of inflammation and subsequent foreign body reaction (FBR) medical implants and tissue engineering constructs.Read moreRead less
Electrochemical biosensors for detection of cardiac disease markers in blood. Cardiovascular diseases leading to heart failure have a prevalence of over 16 per cent in Australia. The social, economic and health burden is higher than for any other disease group. Hence, it is critically important to develop fit-for-purpose sensors of known cardiac biomarkers, which alert patients and clinicians of the risk of imminent heart failure.
Nanoscale silicon field-effect transistor diagnostic technology. This project aims to overcome barriers to the implementation of silicon field-effect transistor biosensors. It will investigate the biosensors’ physical and structural properties. This knowledge, combined with technological and conceptual advances, could foster the development of an advanced and translational point-of-care diagnostic technology to rapidly and sensitively detect malignant tissues. Such technology would have commerci ....Nanoscale silicon field-effect transistor diagnostic technology. This project aims to overcome barriers to the implementation of silicon field-effect transistor biosensors. It will investigate the biosensors’ physical and structural properties. This knowledge, combined with technological and conceptual advances, could foster the development of an advanced and translational point-of-care diagnostic technology to rapidly and sensitively detect malignant tissues. Such technology would have commercial potential and important societal benefits.Read moreRead less
Nanoengineered gradient substrata as a novel approach for understanding infection mechanisms. This project will advance our understanding of how bacteria colonise surfaces and will also inform the development of novel antibacterial coatings and diagnostic tools for device-associated infections, which have a significant impact on patients and are a huge burden to the healthcare system.
Substrate-integrated wearable antennas for unobtrusive activity monitoring. This project aims to develop a novel class of wearable textile antennas that can form robust connections with miniature battery-less motion sensors for non-invasive activity monitoring of older people. In contrast to bulky body worn sensors that must be strapped on, it is anticipated that the garment-integrated textile antennas patterned through computerised embroidery will lead to low-cost, low-profile, and flexible ant ....Substrate-integrated wearable antennas for unobtrusive activity monitoring. This project aims to develop a novel class of wearable textile antennas that can form robust connections with miniature battery-less motion sensors for non-invasive activity monitoring of older people. In contrast to bulky body worn sensors that must be strapped on, it is anticipated that the garment-integrated textile antennas patterned through computerised embroidery will lead to low-cost, low-profile, and flexible antennas that are truly wearable with exceptional performance and scalable manufacturing techniques. The outcomes from the project are expected to underpin innovative applications, such as aged care, providing a means for caregivers to automatically monitor health and physical activity and intervene as required. Such applications would support ageing Australians to live with greater independence and safety.Read moreRead less
Development of a novel flex sensor for use on catheters in medical pressure diagnostic tools. This research project will lead to a significant improvement on the technologies currently available to diagnostic tests of swallowing dysfunctions in children. The proposed technology is much needed and will enable future development of more direct and targeted interventions to assist with feeding based on these measurement techniques. In addition, the knowledge and expertise learned from this project ....Development of a novel flex sensor for use on catheters in medical pressure diagnostic tools. This research project will lead to a significant improvement on the technologies currently available to diagnostic tests of swallowing dysfunctions in children. The proposed technology is much needed and will enable future development of more direct and targeted interventions to assist with feeding based on these measurement techniques. In addition, the knowledge and expertise learned from this project as applied to such a miniature medical device comprises sufficient generic know-how to be useful in developing other biomedical devices. These developments will have a tangible technological impact in a way that will help the Australian biomedical industry be more competitive in the global market.Read moreRead less
A nanoengineered solution to drug delivery in bone. This project presents an exciting new approach of applying nanotechnology to bone research. By combining our expertise in nanoengineering of new materials, mathematical modelling and bone biology, this project will result in a well-characterised model for drug delivery into bone and lead to a new therapeutic approach for treating bone diseases.