Universal quantum imaging. This project will integrate quantum technology with the rapidly advancing techniques of spatial light modulation utilised in LCD displays and video projectors. We will develop, for the first time, broadly versatile imaging technology based on quantum mechanics, enabling both important applications in future medical diagnostic devices and communication systems; and fundamental advances in the biological and quantum sciences. Quantum technologies offer the promise to rev ....Universal quantum imaging. This project will integrate quantum technology with the rapidly advancing techniques of spatial light modulation utilised in LCD displays and video projectors. We will develop, for the first time, broadly versatile imaging technology based on quantum mechanics, enabling both important applications in future medical diagnostic devices and communication systems; and fundamental advances in the biological and quantum sciences. Quantum technologies offer the promise to revolutionise many aspects of modern life, from computing and communications, to medical imaging and metrology. This project will put Australia at the international forefront of quantum imaging, enhancing Australia's already significant international presence in the area.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989648
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Optical test-bed facility for mid infrared components for sensing, imaging and astrophotonics. This test facility will enable Australian researchers to validate optical components and technologies at wavelengths from 2.5 to 20 microns, that are crucial for a wide range of applications including biophotonics, sensing, imaging, defense, and astro-photonics. Technologies related to the Mid IR are
expected to have a significant impact on quality of life and global economy. It will enable Australi ....Optical test-bed facility for mid infrared components for sensing, imaging and astrophotonics. This test facility will enable Australian researchers to validate optical components and technologies at wavelengths from 2.5 to 20 microns, that are crucial for a wide range of applications including biophotonics, sensing, imaging, defense, and astro-photonics. Technologies related to the Mid IR are
expected to have a significant impact on quality of life and global economy. It will enable Australian researchers to achieve a major impact in many areas of Mid IR fundamental and applied science as well as industry sectors such as sensing, biophotonics, defence, health, bio-security and imaging. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0237527
Funder
Australian Research Council
Funding Amount
$170,000.00
Summary
Bioscope IV : Advanced Scanned Probe Microscopy. The Atomic Force Microscope presents a unique view of the microscopic and molecular world, for it is sensitive to force alone. This instrument can accurately map force over a surface at the molecular scale; picoNewtons at nanometre resolution. The host of intermolecular forces which cause phenomena such as self-assembly, colloid stability, cell interactions and friction are only directly measurable with this technique. In this field of force meas ....Bioscope IV : Advanced Scanned Probe Microscopy. The Atomic Force Microscope presents a unique view of the microscopic and molecular world, for it is sensitive to force alone. This instrument can accurately map force over a surface at the molecular scale; picoNewtons at nanometre resolution. The host of intermolecular forces which cause phenomena such as self-assembly, colloid stability, cell interactions and friction are only directly measurable with this technique. In this field of force measurement Australian researchers are leaders. The proposed instrument expands the capabilities of this effort, and develops exciting new directions including the direct manipulation of molecules through a novel feedback and control (haptic) interface.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560818
Funder
Australian Research Council
Funding Amount
$154,000.00
Summary
A Pico-Newton Scale Force Measurement Apparatus for Polymer Physics and Non-equilibrium Statistical Mechanics. We propose to build a state-of-the-art Optical Tweezers apparatus that measures small forces and torques on micron-sized objects located in 'optical traps'. Using a single laser beam and computer-generated holograms, we will create arrays of optical traps that move or 'dance', and alter the force/torque-imposing properties of each trap. This proposed research equipment will be used (1 ....A Pico-Newton Scale Force Measurement Apparatus for Polymer Physics and Non-equilibrium Statistical Mechanics. We propose to build a state-of-the-art Optical Tweezers apparatus that measures small forces and torques on micron-sized objects located in 'optical traps'. Using a single laser beam and computer-generated holograms, we will create arrays of optical traps that move or 'dance', and alter the force/torque-imposing properties of each trap. This proposed research equipment will be used (1) to study the physics of single synthetic polymer and naturally occuring biopolymer chains, (2) to quantify experimentally, and for the first time, newly predicted molecular-scale forces, and (3) to demonstrate new theories in non-equilibrium statistical mechanics that quantitatively describe the operation of nanomachines. Read moreRead less
Dynamic Force Microscopy of small molecular assemblies. The possibility of manipulating a single molecule seems at first unreal, indeed 5 years ago it was pure science fiction. Through the gaining popularity of the Atomic Force Microscope (AFM) many perspectives about the molecular world are changing. Macroscopic effects such as adhesion and lubrication are now discussed in light of measurements made with this instrument. Newer work includes the observation of single protein unfolding experim ....Dynamic Force Microscopy of small molecular assemblies. The possibility of manipulating a single molecule seems at first unreal, indeed 5 years ago it was pure science fiction. Through the gaining popularity of the Atomic Force Microscope (AFM) many perspectives about the molecular world are changing. Macroscopic effects such as adhesion and lubrication are now discussed in light of measurements made with this instrument. Newer work includes the observation of single protein unfolding experiments. The biophysics oriented project detailed in this application will extend the AFM: into multi-molecular systems formed by self-assembly, such as cell membranes; into polyelectrolyte-surface interactions; and, finally into the sequencing of DNA.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882289
Funder
Australian Research Council
Funding Amount
$520,000.00
Summary
New generation mass spectrometers for characterisation of molecular shape and size. The ion mobility mass spectrometer (IMMS at UOW) will be the first of its kind in Australia, and together with the ion trap mass spectrometer (ITMS at ANU) will continue the tradition of this partnership in providing researchers with cutting-edge instrumentation for nationally and internationally important projects including: (i) fundamental understanding of the ways in which biomolecules recognize one another, ( ....New generation mass spectrometers for characterisation of molecular shape and size. The ion mobility mass spectrometer (IMMS at UOW) will be the first of its kind in Australia, and together with the ion trap mass spectrometer (ITMS at ANU) will continue the tradition of this partnership in providing researchers with cutting-edge instrumentation for nationally and internationally important projects including: (i) fundamental understanding of the ways in which biomolecules recognize one another, (ii) investigating the structure(s) of lipids (fats) in cardiovascular disease and cataract, (iii) developing anticancer drugs, and (iv) development of new materials.Read moreRead less
ARC Centre of Excellence - Coherent X-ray Science. The twenty first century is said to be the century of biology. And there is no doubt that the development of our understanding of biological system is continuing at a massive rate. However as our understanding deepens, we need to draw on the whole range of scientific disciplines to proceed. This Centre draws together a multidisciplinary team of world-leading scientists to address one the key questions in modern biology, the structure of a membra ....ARC Centre of Excellence - Coherent X-ray Science. The twenty first century is said to be the century of biology. And there is no doubt that the development of our understanding of biological system is continuing at a massive rate. However as our understanding deepens, we need to draw on the whole range of scientific disciplines to proceed. This Centre draws together a multidisciplinary team of world-leading scientists to address one the key questions in modern biology, the structure of a membrane protein. We will develop techniques based on the latest developments in theoretical physics & chemistry, imaging, biology and technology - including the new Australian Synchrotron - to create new approaches to structural biology.Read moreRead less
Electron and Positron Interactions with Bio-Molecules. This program of research will quantify reaction rates and elucidate reaction pathways for a range of important processes in our bodies involving ionising radiation. It will lead to a greatly improved understanding of positron and electron interactions with biological systems, including DNA and its constituent molecules and, through a better understanding of the underlying fundamental interactions, will lay foundations for improvements in te ....Electron and Positron Interactions with Bio-Molecules. This program of research will quantify reaction rates and elucidate reaction pathways for a range of important processes in our bodies involving ionising radiation. It will lead to a greatly improved understanding of positron and electron interactions with biological systems, including DNA and its constituent molecules and, through a better understanding of the underlying fundamental interactions, will lay foundations for improvements in technologies such as PET imaging. Read moreRead less